Integrin targeted drug and gene delivery

Systemic siRNA delivery to leukocyte-implicated diseases

(2011) Dan Peer et al.   CELL CYCLE

Infarction of tumor vessels by NGR-peptide-directed targeting of tissue factor: experimental results and first-in-man experience

(2009) R. Bieker et al.   BLOOD

 v 3/ v 5 Integrins-FAK-RhoB: A Novel Pathway for Hypoxia Regulation in Glioblastoma

(2009) N. Skuli et al.   CANCER RESEARCH

T.86. siRNA Delivery with Integrin LFA-1-targeted Nanoparticles Prevents HIV Infection in Humanized Mice

(2009) Sang-Soo Kim et al.   CLINICAL IMMUNOLOGY

Inflammation, Microenvironment, and the Immune System in Cancer Progression

(2009) Andrew Keibel et al.   CURRENT PHARMACEUTICAL DESIGN

Targeted delivery of thrombolytic agents: role of integrin receptors

(2009) Suresh P Vyas et al.   Expert Opinion on Drug Delivery

Inhibition of vimentin or  1 integrin reverts morphology of prostate tumor cells grown in laminin-rich extracellular matrix gels and reduces tumor growth in vivo

(2009) X. Zhang et al.   MOLECULAR CANCER THERAPEUTICS

Single Subcutaneous Administration of RGDK-Lipopeptide:rhPDGF-B Gene Complex Heals Wounds in Streptozotocin-Induced Diabetic Rats

(2009) Jayanta Bhattacharyya et al.   MOLECULAR PHARMACEUTICS

Design of a Multifunctional PLGA Nanoparticulate Drug Delivery System: Evaluation of its Physicochemical Properties and Anticancer Activity to Malignant Cancer Cells

(2009) Zhe Wang et al.   PHARMACEUTICAL RESEARCH

Selectins Ligand Decorated Drug Carriers for Activated Endothelial Cell Targeting

(2008) Xavier Banquy et al.   BIOCONJUGATE CHEMISTRY

Cellular Delivery and Biological Activity of Antisense Oligonucleotides Conjugated to a Targeted Protein Carrier

(2008) Hyunmin Kang et al.   BIOCONJUGATE CHEMISTRY

Self-assembled glycol chitosan nanoparticles for the sustained and prolonged delivery of antiangiogenic small peptide drugs in cancer therapy

(2008) Jong-Ho Kim et al.   BIOMATERIALS

Pharmacology of the Novel Antiangiogenic Peptide ATN-161 (Ac-PHSCN-NH2): Observation of a U-Shaped Dose-Response Curve in Several Preclinical Models of Angiogenesis and Tumor Growth

(2008) F. Donate et al.   CLINICAL CANCER RESEARCH

Integrin αvβ3-targeted cancer therapy

(2008) Zhaofei Liu et al.   DRUG DEVELOPMENT RESEARCH

Evaluation of biodistribution and anti-tumor effect of a dimeric RGD peptide–paclitaxel conjugate in mice with breast cancer

(2008) Qizhen Cao et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Phase I Clinical Trial of Cilengitide in Children With Refractory Brain Tumors: Pediatric Brain Tumor Consortium Study PBTC-012

(2008) Tobey J. MacDonald et al.   JOURNAL OF CLINICAL ONCOLOGY

RGD-based strategies for improving antitumor activity of paclitaxel-loaded liposomes in nude mice xenografted with human ovarian cancer

(2008) Hui Zhao et al.   JOURNAL OF DRUG TARGETING

Lipopeptide with a RGDK Tetrapeptide Sequence Can Selectively Target Genes to Proangiogenic α5β1 Integrin Receptor and Mouse Tumor Vasculature

(2008) Dipankar Pramanik et al.   JOURNAL OF MEDICINAL CHEMISTRY

RGD-IL-24, A Novel Tumor-Targeted Fusion Cytokine: Expression, Purification and Functional Evaluation

(2008) Bin Xiao et al.   MOLECULAR BIOTECHNOLOGY

Anti-integrin monoclonal antibody CNTO 95 enhances the therapeutic efficacy of fractionated radiation therapy in vivo

(2008) Shoucheng Ning et al.   MOLECULAR CANCER THERAPEUTICS

Nanoparticle-mediated drug delivery to tumor vasculature suppresses metastasis

(2008) E. A. Murphy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic Leukocyte-Directed siRNA Delivery Revealing Cyclin D1 as an Anti-Inflammatory Target

(2008) D. Peer et al.   SCIENCE