Amyloid-directed monoclonal antibodies for the treatment of Alzheimer’s disease: the point of no return?
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Title
Amyloid-directed monoclonal antibodies for the treatment of Alzheimer’s disease: the point of no return?
Authors
Keywords
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Journal
EXPERT OPINION ON BIOLOGICAL THERAPY
Volume 14, Issue 10, Pages 1465-1476
Publisher
Informa Healthcare
Online
2014-07-02
DOI
10.1517/14712598.2014.935332
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Note: Only part of the references are listed.- Is there still any hope for amyloid-based immunotherapy for Alzheimerʼs disease?
- (2014) Francesco Panza et al. CURRENT OPINION IN PSYCHIATRY
- Amyloid-based immunotherapy for Alzheimer's disease in the time of prevention trials: the way forward
- (2014) Francesco Panza et al. Expert Review of Clinical Immunology
- Advances in the prevention of Alzheimer's disease and dementia
- (2014) A. Solomon et al. JOURNAL OF INTERNAL MEDICINE
- Clinical trials and late-stage drug development for Alzheimer's disease: an appraisal from 1984 to 2014
- (2014) L. S. Schneider et al. JOURNAL OF INTERNAL MEDICINE
- Lessons from immunotherapy for Alzheimer disease
- (2014) Yan-Jiang Wang Nature Reviews Neurology
- Antiamyloid Therapy for Alzheimer's Disease — Are We on the Right Road?
- (2014) Eric Karran et al. NEW ENGLAND JOURNAL OF MEDICINE
- Two Phase 3 Trials of Bapineuzumab in Mild-to-Moderate Alzheimer's Disease
- (2014) Stephen Salloway et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase 3 Trials of Solanezumab for Mild-to-Moderate Alzheimer's Disease
- (2014) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- Longitudinal Change in CSF Biomarkers in Autosomal-Dominant Alzheimer's Disease
- (2014) A. M. Fagan et al. Science Translational Medicine
- The A4 Study: Stopping AD Before Symptoms Begin?
- (2014) R. A. Sperling et al. Science Translational Medicine
- Vascular Risk Factors
- (2013) Jack C. de la Torre American Journal of Alzheimers Disease and Other Dementias
- Bapineuzumab and solanezumab for Alzheimer's disease: is the ‘amyloid cascade hypothesis' still alive?
- (2013) Haythum O Tayeb et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study
- (2013) Victor L Villemagne et al. LANCET NEUROLOGY
- Immunotherapy for Alzheimer’s disease: hoops and hurdles
- (2013) Cynthia A Lemere Molecular Neurodegeneration
- Review: Cerebral amyloid angiopathy, prion angiopathy, CADASIL and the spectrum of protein elimination failure angiopathies (PEFA) in neurodegenerative disease with a focus on therapy
- (2013) R. O. Carare et al. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY
- Regulatory Innovation and Drug Development for Early-Stage Alzheimer's Disease
- (2013) Nicholas Kozauer et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Phase 3 Trial of Semagacestat for Treatment of Alzheimer's Disease
- (2013) Rachelle S. Doody et al. NEW ENGLAND JOURNAL OF MEDICINE
- Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial
- (2013) S.M. Mills et al. REVUE NEUROLOGIQUE
- Changes in Amyloid- and Tau in the Cerebrospinal Fluid of Transgenic Mice Overexpressing Amyloid Precursor Protein
- (2013) L. F. Maia et al. Science Translational Medicine
- Dominantly Inherited Alzheimer Network: facilitating research and clinical trials
- (2013) Krista L Moulder et al. Alzheimers Research & Therapy
- Passive anti-amyloid immunotherapy in Alzheimer's disease: What are the most promising targets?
- (2013) Jens Moreth et al. Immunity & Ageing
- Safety and biomarker effects of solanezumab in patients with Alzheimer’s disease
- (2012) Martin Farlow et al. Alzheimers & Dementia
- Brain injury biomarkers are not dependent on β-amyloid in normal elderly
- (2012) David S. Knopman et al. ANNALS OF NEUROLOGY
- Amyloid-β–Associated Clinical Decline Occurs Only in the Presence of Elevated P-tau
- (2012) Rahul S. Desikan et al. ARCHIVES OF NEUROLOGY
- Effect of Immunotherapy With Bapineuzumab on Cerebrospinal Fluid Biomarker Levels in Patients With Mild to Moderate Alzheimer Disease
- (2012) Henrik Zetterberg ARCHIVES OF NEUROLOGY
- Safety and Tolerability of the γ-Secretase Inhibitor Avagacestat in a Phase 2 Study of Mild to Moderate Alzheimer Disease
- (2012) Vladimir Coric et al. ARCHIVES OF NEUROLOGY
- Gantenerumab for the treatment of Alzheimer's disease
- (2012) Julien Delrieu et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Solanezumab for the treatment of mild-to-moderate Alzheimer’s disease
- (2012) Bruno P Imbimbo et al. Expert Review of Clinical Immunology
- Immunotherapy for Alzheimer’s disease: from anti-β-amyloid to tau-based immunization strategies
- (2012) Francesco Panza et al. Immunotherapy
- Anti-apoE immunotherapy inhibits amyloid accumulation in a transgenic mouse model of Aβ amyloidosis
- (2012) Jungsu Kim et al. JOURNAL OF EXPERIMENTAL MEDICINE
- An Effector-Reduced Anti- -Amyloid (A ) Antibody with Unique A Binding Properties Promotes Neuroprotection and Glial Engulfment of A
- (2012) O. Adolfsson et al. JOURNAL OF NEUROSCIENCE
- Preclinical Alzheimer disease—the challenges ahead
- (2012) Reisa A. Sperling et al. Nature Reviews Neurology
- Deciphering the mechanism underlying late-onset Alzheimer disease
- (2012) Dimitrije Krstic et al. Nature Reviews Neurology
- Immunization targeting a minor plaque constituent clears β-amyloid and rescues behavioral deficits in an Alzheimer's disease mouse model
- (2012) Jose Morales-Corraliza et al. NEUROBIOLOGY OF AGING
- Passive Immunization against Pyroglutamate-3 Amyloid-ß Reduces Plaque Burden in Alzheimer-Like Transgenic Mice: A Pilot Study
- (2012) Jeffrey L. Frost et al. Neurodegenerative Diseases
- Short-term clinical outcomes for stages of NIA-AA preclinical Alzheimer disease
- (2012) D. S. Knopman et al. NEUROLOGY
- A Plaque-Specific Antibody Clears Existing β-amyloid Plaques in Alzheimer's Disease Mice
- (2012) Ronald B. DeMattos et al. NEURON
- Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease
- (2012) Randall J. Bateman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Perivascular drainage of solutes is impaired in the ageing mouse brain and in the presence of cerebral amyloid angiopathy
- (2011) Cheryl A. Hawkes et al. ACTA NEUROPATHOLOGICA
- Amyloid-related imaging abnormalities in amyloid-modifying therapeutic trials: Recommendations from the Alzheimer’s Association Research Roundtable Workgroup
- (2011) Reisa A. Sperling et al. Alzheimers & Dementia
- Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Reisa A. Sperling et al. Alzheimers & Dementia
- The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Marilyn S. Albert et al. Alzheimers & Dementia
- An operational approach to National Institute on Aging-Alzheimer's Association criteria for preclinical Alzheimer disease
- (2011) Clifford R. Jack et al. ANNALS OF NEUROLOGY
- Mechanism of Amyloid Removal in Patients With Alzheimer Disease Treated With Gantenerumab
- (2011) Susanne Ostrowitzki ARCHIVES OF NEUROLOGY
- Anti-β-Amyloid Immunotherapy for Alzheimers Disease: Focus on Bapineuzumab
- (2011) Francesco Panza et al. Current Alzheimer Research
- Autoreactive-Aβ antibodies promote APP β-secretase processing
- (2011) Juan Deng et al. JOURNAL OF NEUROCHEMISTRY
- Testing the Right Target and Right Drug at the Right Stage
- (2011) R. A. Sperling et al. Science Translational Medicine
- Safety and Changes in Plasma and Cerebrospinal Fluid Amyloid β After a Single Administration of an Amyloid β Monoclonal Antibody in Subjects With Alzheimer Disease
- (2010) Eric R. Siemers et al. CLINICAL NEUROPHARMACOLOGY
- Towards Disease-Modifying Treatment of Alzheimers Disease: Drugs Targeting β -Amyloid
- (2010) V. Frisardi et al. Current Alzheimer Research
- Antioxidant approaches for the treatment of Alzheimer’s disease
- (2010) Hyun Pil Lee et al. Expert Review of Neurotherapeutics
- 11C-PiB PET assessment of change in fibrillar amyloid-β load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study
- (2010) Juha O Rinne et al. LANCET NEUROLOGY
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- A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease
- (2009) S. Salloway et al. NEUROLOGY
- Oligomeric amyloid associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques
- (2009) R. M. Koffie et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Consequence of Aβ immunization on the vasculature of human Alzheimer's disease brain
- (2008) D. Boche et al. BRAIN
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