Therapeutic antibodies to intracellular targets in cancer therapy

Targeting the Intracellular WT1 Oncogene Product with a Therapeutic Human Antibody

(2013) T. Dao et al.   Science Translational Medicine

Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1+ leukemias

(2012) E. Doubrovina et al.   BLOOD

Intracellular Tumor-Associated Antigens Represent Effective Targets for Passive Immunotherapy

(2012) T. Noguchi et al.   CANCER RESEARCH

T-cell-receptor-like antibodies – generation, function and applications

(2012) Rony Dahan et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

An anti-PR1/HLA-A2 T-cell receptor-like antibody mediates complement-dependent cytotoxicity against acute myeloid leukemia progenitor cells

(2011) A. Sergeeva et al.   BLOOD

TCR Mimic Monoclonal Antibodies Induce Apoptosis of Tumor Cells via Immune Effector-Independent Mechanisms

(2011) B. Verma et al.   JOURNAL OF IMMUNOLOGY

Targeting Intracellular Oncoproteins with Antibody Therapy or Vaccination

(2011) K. Guo et al.   Science Translational Medicine

WT1 (Wilms' Tumor Gene 1): Biology and Cancer Immunotherapy

(2010) H. Sugiyama   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

Engineered therapeutic antibodies with improved effector functions

(2009) Tsuguo Kubota et al.   CANCER SCIENCE

Antitumor Activity of Immunotoxins with T-Cell Receptor-like Specificity against Human Melanoma Xenografts

(2008) E. Klechevsky et al.   CANCER RESEARCH

Targeting TARP, a novel breast and prostate tumor-associated antigen, with T cell receptor-like human recombinant antibodies

(2008) Malka Epel et al.   EUROPEAN JOURNAL OF IMMUNOLOGY