Targeted biological therapies for pain

Analgesic Effect of Highly Reversible ω-Conotoxin FVIA on N Type Ca2+ Channels

(2011) Seungkyu Lee et al.   Molecular Pain

RNA interference-mediated gene silence of the NR1 subunit of the NMDA receptor by subcutaneous injection of vector-encoding short hairpin RNA reduces formalin-induced nociception in the rat

(2011) Ping-Heng Tan et al.   PAIN

Ziconotide Combination Intrathecal Therapy: Rationale and Evidence

(2010) Mark S. Wallace et al.   CLINICAL JOURNAL OF PAIN

Nociceptors: the sensors of the pain pathway

(2010) Adrienne E. Dubin et al.   JOURNAL OF CLINICAL INVESTIGATION

Safety and efficacy of intrathecal ziconotide in the management of severe chronic pain

(2010) Howard Howard Smith   Therapeutics and Clinical Risk Management

Intrathecal Ziconotide for Severe Chronic Pain: Safety and Tolerability Results of an Open-Label, Long-Term Trial

(2009) Mark S. Wallace et al.   ANESTHESIA AND ANALGESIA

Reduction of Allodynia by Intrathecal Transplantation of Microencapsulated Porcine Chromaffin Cells

(2009) Yu Mi Kim et al.   ARTIFICIAL ORGANS

Effective neuropathic pain relief through sciatic nerve administration of GAD65-expressing rAAV2

(2009) Jaehyung Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Herpes virus-based recombinant herpes vectors: gene therapy for pain and molecular tool for pain science

(2009) D C Yeomans et al.   GENE THERAPY

Long-term control of neuropathic pain in a non-viral gene therapy paradigm

(2009) E M Sloane et al.   GENE THERAPY

A human trial of HSV-mediated gene transfer for the treatment of chronic pain

(2009) D Wolfe et al.   GENE THERAPY

AAV for pain: steps towards clinical translation

(2009) A S Beutler et al.   GENE THERAPY

Adenovector GAD65 Gene Delivery into the Rat Trigeminal Ganglion Produces Orofacial Analgesia

(2009) Jean-Philippe Vit et al.   Molecular Pain

Peripheral Non-Viral MIDGE Vector-Driven Delivery of β-Endorphin in Inflammatory Pain

(2009) Halina Machelska et al.   Molecular Pain

Effective Relief of Neuropathic Pain by Adeno-Associated Virus-Mediated Expression of a Small Hairpin Rna against GTP Cyclohydrolase 1

(2009) Sung Jin Kim et al.   Molecular Pain

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

A Clinical Trial of Gene Therapy for Chronic Pain

(2009) Darren Wolfe et al.   PAIN MEDICINE

Voltage-Gated Sodium Channels: Therapeutic Targets for Pain

(2009) Sulayman D. Dib-Hajj et al.   PAIN MEDICINE

Intrathecal Therapy: What Has Changed With the Introduction of Ziconotide

(2009) Hans G. Kress et al.   Pain Practice

Toxins from cone snails: properties, applications and biotechnological production

(2008) Stefan Becker et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Spinal subarachnoid adrenal medullary transplants reduce hind paw swelling and peripheral nerve transport following formalin injection in rats

(2008) Uri Herzberg et al.   BRAIN RESEARCH

Herpes Vector–mediated Gene Transfer in the Treatment of Chronic Pain

(2008) Joseph C Glorioso et al.   MOLECULAR THERAPY

Motor cortex stimulation for chronic pain: Systematic review and meta-analysis of the literature

(2008) M. C. Lima et al.   NEUROLOGY

Gene therapy directed at the neuroimmune component of chronic pain with particular attention to the role of TNFα

(2008) Marina Mata et al.   NEUROSCIENCE LETTERS

A novel human foamy virus mediated gene transfer of GAD67 reduces neuropathic pain following spinal cord injury

(2008) Wanhong Liu et al.   NEUROSCIENCE LETTERS

Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain

(2008) B. Storek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA