Microenvironmental targeting of Wnt/β-catenin signals for hematopoietic stem cell regulation

Intramarrow injection of β-catenin-activated, but not naïve mesenchymal stromal cells stimulates self-renewal of hematopoietic stem cells in bone marrow

(2010) Ji-Yeon Ahn et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Undifferentiated hematopoietic cells are characterized by a genome-wide undermethylation dip around the transcription start site and a hierarchical epigenetic plasticity

(2009) Y. S. Chung et al.   BLOOD

Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/- mice in vivo

(2009) Y. Li et al.   BLOOD

Wnt-Related Molecules and Signaling Pathway Equilibrium in Hematopoiesis

(2009) Sachin Malhotra et al.   Cell Stem Cell

Non-canonical Wnt signaling pathways in hematopoiesis

(2009) Kathleen Kokolus et al.   IMMUNOLOGIC RESEARCH

β-Catenin Expression in the Bone Marrow Microenvironment Is Required for Long-Term Maintenance of Primitive Hematopoietic Cells

(2009) Michael J. Nemeth et al.   STEM CELLS

Identification of a Stroma-Mediated Wnt/β-Catenin Signal Promoting Self-Renewal of Hematopoietic Stem Cells in the Stem Cell Niche

(2009) Jin-A Kim et al.   STEM CELLS

Osteolineage niche cells initiate hematopoietic stem cell mobilization

(2008) S. R. Mayack et al.   BLOOD

Defective Notch activation in microenvironment leads to myeloproliferative disease

(2008) Y.-W. Kim et al.   BLOOD

Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation

(2008) T. C. Luis et al.   BLOOD

Nf2/Merlin Regulates Hematopoietic Stem Cell Behavior by Altering Microenvironmental Architecture

(2008) Jonas Larsson et al.   Cell Stem Cell

Canonical Notch Signaling Is Dispensable for the Maintenance of Adult Hematopoietic Stem Cells

(2008) Ivan Maillard et al.   Cell Stem Cell

Wnt Signaling in the Niche Enforces Hematopoietic Stem Cell Quiescence and Is Necessary to Preserve Self-Renewal In Vivo

(2008) Heather E. Fleming et al.   Cell Stem Cell

Wnt/β-catenin signaling: new (and old) players and new insights

(2008) He Huang et al.   CURRENT OPINION IN CELL BIOLOGY

Evolving concepts on the microenvironmental niche for hematopoietic stem cells

(2008) Marc HGP Raaijmakers et al.   CURRENT OPINION IN HEMATOLOGY

The Extracellular Domain of Lrp5/6 Inhibits Noncanonical Wnt Signaling In Vivo

(2008) Vitezslav Bryja et al.   MOLECULAR BIOLOGY OF THE CELL

Live-animal tracking of individual haematopoietic stem/progenitor cells in their niche

(2008) Cristina Lo Celso et al.   NATURE

Detection of functional haematopoietic stem cell niche using real-time imaging

(2008) Yucai Xie et al.   NATURE

Endochondral ossification is required for haematopoietic stem-cell niche formation

(2008) Charles K. F. Chan et al.   NATURE