Re-targeting T-cells against cancer by gene-transfer of tumor-reactive receptors

Human TCR That Incorporate CD3  Induce Highly Preferred Pairing between TCR  and   Chains following Gene Transfer

(2014) Z. Sebestyen et al.   JOURNAL OF IMMUNOLOGY

Increasing functional avidity of TCR-redirected T cells by removing definedN-glycosylation sites in the TCR constant domain

(2009) Jürgen Kuball et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Different T Cell Receptor Signals Determine CD8+ Memory Versus Effector Development

(2009) E. Teixeiro et al.   SCIENCE

Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells

(2008) B. G. Till et al.   BLOOD

IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes

(2008) S. Kaneko et al.   BLOOD

Adoptive transfer of effector CD8+ T cells derived from central memory cells establishes persistent T cell memory in primates

(2008) Carolina Berger et al.   JOURNAL OF CLINICAL INVESTIGATION

Structural features of T cell receptor variable regions that enhance domain stability and enable expression as single-chain VαVβ fragments

(2008) Sarah A. Richman et al.   MOLECULAR IMMUNOLOGY

Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma

(2008) Martin A Pule et al.   NATURE MEDICINE