Sarcoplasmic reticulum Ca2+ATPase as a therapeutic target for heart failure

Long-Term Cardiac-Targeted RNA Interference for the Treatment of Heart Failure Restores Cardiac Function and Reduces Pathological Hypertrophy

(2009) Lennart Suckau et al.   CIRCULATION

Inducible Expression of Active Protein Phosphatase-1 Inhibitor-1 Enhances Basal Cardiac Function and Protects Against Ischemia/Reperfusion Injury

(2009) Persoulla Nicolaou et al.   CIRCULATION RESEARCH

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID Trial), a First-in-Human Phase 1/2 Clinical Trial

(2009) Brian E. Jaski et al.   JOURNAL OF CARDIAC FAILURE

Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology

(2009) Persoulla Nicolaou et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A myocardium tropic adeno-associated virus (AAV) evolved by DNA shuffling and in vivo selection

(2009) L. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo

(2008) J. Michael O'Donnell et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Rescue of Ca2+ overload-induced left ventriclur dysfunction by targeted ablation of phospholamban

(2008) Tsuyoshi Tsuji et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Prevention of Ventricular Arrhythmias With Sarcoplasmic Reticulum Ca 2+ ATPase Pump Overexpression in a Porcine Model of Ischemia Reperfusion

(2008) Fabrice Prunier et al.   CIRCULATION

Gene Therapy in Heart Failure

(2008) Leif Erik Vinge et al.   CIRCULATION RESEARCH

Endothelial S100A1 Modulates Vascular Function via Nitric Oxide

(2008) Sven T. Pleger et al.   CIRCULATION RESEARCH

Optimizing gene delivery vectors for the treatment of heart disease

(2008) Steven J Gray et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals

(2008) M J Byrne et al.   GENE THERAPY

Intracellular devastation in heart failure

(2008) Federica del Monte et al.   HEART FAILURE REVIEWS

Design of a Phase 1/2 Trial of Intracoronary Administration of AAV1/SERCA2a in Patients With Heart Failure

(2008) Roger J. Hajjar et al.   JOURNAL OF CARDIAC FAILURE

Modulation of Sarcoplasmic Reticulum Function by PST2744 [Istaroxime; (E,Z)-3-((2-Aminoethoxy)imino) Androstane-6,17-dione Hydrochloride)] in a Pressure-Overload Heart Failure Model

(2008) M. Rocchetti et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Cardiac Contractility Modulation Electrical Signals Improve Myocardial Gene Expression in Patients With Heart Failure

(2008) Christian Butter et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Myocardial Gene Expression in Heart Failure Patients Treated With Cardiac Resynchronization Therapy

(2008) Marc Vanderheyden et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Reversal of Cardiac Dysfunction After Long-Term Expression of SERCA2a by Gene Transfer in a Pre-Clinical Model of Heart Failure

(2008) Yoshiaki Kawase et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Recombinant Adeno-associated Virus Transduction and Integration

(2008) Brian R Schultz et al.   MOLECULAR THERAPY

Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles

(2008) Wuping Li et al.   MOLECULAR THERAPY

DNA Shuffling of Adeno-associated Virus Yields Functionally Diverse Viral Progeny

(2008) James T Koerber et al.   MOLECULAR THERAPY

Role of sarco/endoplasmic reticulum calcium content and calcium ATPase activity in the control of cell growth and proliferation

(2008) Larissa Lipskaia et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases

(2008) Yoshiaki Kawase et al.   Nature clinical practice. Cardiovascular medicine

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology

Heart Disease and Stroke Statistics—2008 Update

(2007) et al.   CIRCULATION

Gene therapy: targeting the myocardium

(2007) A R Lyon et al.   HEART

Early and late effects of cardiac resynchronization therapy on force–frequency relation and contractility regulating gene expression in heart failure patients

(2007) Wilfried Mullens et al.   HEART RHYTHM