The glutamatergic system as a target for neuropathic pain relief

Evidence That Spinal Astrocytes but Not Microglia Contribute to the Pathogenesis of Paclitaxel-Induced Painful Neuropathy

(2012) Haijun Zhang et al.   JOURNAL OF PAIN

EAAT expression by macrophages and microglia: still more questions than answers

(2011) Gabriel Gras et al.   AMINO ACIDS

Intrathecal Etanercept Partially Restores Morphineʼs Antinociception in Morphine-Tolerant Rats via Attenuation of the Glutamatergic Transmission

(2011) Ching-Hui Shen et al.   ANESTHESIA AND ANALGESIA

Intrathecal Ultra-Low Dose Naloxone Enhances the Antinociceptive Effect of Morphine by Enhancing the Reuptake of Excitatory Amino Acids from the Synaptic Cleft in the Spinal Cord of Partial Sciatic Nerve–Transected Rats

(2011) Chih-Ping Yang et al.   ANESTHESIA AND ANALGESIA

Intrathecal Injection of Metabotropic Glutamate Receptor Subtype 3 and 5 Agonist/Antagonist Attenuates Bone Cancer Pain by Inhibition of Spinal Astrocyte Activation in a Mouse Model

(2011) Bing-xu Ren et al.   ANESTHESIOLOGY

Microglia: A Promising Target for Treating Neuropathic and Postoperative Pain, and Morphine Tolerance

(2011) Yeong-Ray Wen et al.   JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION

mGlu2 Metabotropic Glutamate Receptors Restrain Inflammatory Pain and Mediate the Analgesic Activity of Dual mGlu2/mGlu3 Receptor Agonists

(2011) Magda Zammataro et al.   Molecular Pain

The beta-lactam antibiotic, ceftriaxone, inhibits the development of opioid-induced hyperalgesia in mice

(2011) Zhijun Chen et al.   NEUROSCIENCE LETTERS

Glutamatergic fine tuning with ADX-10059: a novel therapeutic approach for migraine?

(2010) Juana CA Marin et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Impairment of VGLUT2 but not VGLUT1 signaling reduces neuropathy-induced hypersensitivity

(2009) Sandra Leo et al.   EUROPEAN JOURNAL OF PAIN

Differential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain

(2009) Joanna Mika et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Metabotropic Glutamate Receptor Subtype 5 Antagonist Fenobam Is Analgesic and Has Improved in Vivo Selectivity Compared with the Prototypical Antagonist 2-Methyl-6-(phenylethynyl)-pyridine

(2009) M. C. Montana et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Unbearable lightness of touch

(2009) Liam J. Drew et al.   NATURE

Glial inhibitors influence the mRNA and protein levels of mGlu2/3, 5 and 7 receptors and potentiate the analgesic effects of their ligands in a mouse model of neuropathic pain

(2009) Maria Osikowicz et al.   PAIN

Vesicular Glutamate Transporter Acts as a Metabolic Regulator

(2008) Yoshinori Moriyama et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Propentofylline-induced astrocyte modulation leads to alterations in glial glutamate promoter activation following spinal nerve transection

(2008) V.L. Tawfik et al.   NEUROSCIENCE

Glutamate receptor ligands attenuate allodynia and hyperalgesia and potentiate morphine effects in a mouse model of neuropathic pain

(2008) Maria Osikowicz et al.   PAIN

Group III metabotropic glutamate receptors inhibit hyperalgesia in animal models of inflammation and neuropathic pain

(2007) Cyril Goudet et al.   PAIN