The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels

Small-molecule activators of TMEM16A, a calcium-activated chloride channel, stimulate epithelial chloride secretion and intestinal contraction

(2011) Wan Namkung et al.   FASEB JOURNAL

Ca2+-activated Cl− currents are dispensable for olfaction

(2011) Gwendolyn M Billig et al.   NATURE NEUROSCIENCE

Voltage- and calcium-dependent gating of TMEM16A/Ano1 chloride channels are physically coupled by the first intracellular loop

(2011) Q. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression profile and protein translation of TMEM16A in murine smooth muscle

(2010) Alison J. Davis et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

ANO1 amplification and expression in HNSCC with a high propensity for future distant metastasis and its functions in HNSCC cell lines

(2010) C Ayoub et al.   BRITISH JOURNAL OF CANCER

Tmem16AEncodes the Ca2+-activated Cl−Channel in Mouse Submandibular Salivary Gland Acinar Cells

(2010) Victor G. Romanenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TMEM16A Inhibitors Reveal TMEM16A as a Minor Component of Calcium-activated Chloride Channel Conductance in Airway and Intestinal Epithelial Cells

(2010) Wan Namkung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification and Functional Characterization of TMEM16A, a Ca2+-activated Cl−Channel Activated by Extracellular Nucleotides, in Biliary Epithelium

(2010) Amal K. Dutta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystic Fibrosis Transmembrane Regulator Inhibitors CFTRinh-172 and GlyH-101 Target Mitochondrial Functions, Independently of Chloride Channel Inhibition

(2010) M. Kelly et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Calcium concentration jumps reveal dynamic ion selectivity of calcium-activated chloride currents in mouse olfactory sensory neurons and TMEM16b-transfected HEK 293T cells

(2010) Claudia Sagheddu et al.   JOURNAL OF PHYSIOLOGY-LONDON

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

TMEM16A Protein: A New Identity for Ca2+-Dependent Cl− Channels

(2010) Loretta Ferrera et al.   PHYSIOLOGY

Regulation of TMEM16A Chloride Channel Properties by Alternative Splicing

(2009) Loretta Ferrera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transmembrane Protein 16A (TMEM16A) Is a Ca2+-regulated Cl–Secretory Channel in Mouse Airways

(2009) Jason R. Rock et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of TMEM16A Causes a Defect in Epithelial Ca2+-dependent Chloride Transport

(2009) Jiraporn Ousingsawat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TMEM16B, A Novel Protein with Calcium-Dependent Chloride Channel Activity, Associates with a Presynaptic Protein Complex in Photoreceptor Terminals

(2009) H. Stohr et al.   JOURNAL OF NEUROSCIENCE

Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles

(2009) Sung Jin Hwang et al.   JOURNAL OF PHYSIOLOGY-LONDON

Chloride channels as drug targets

(2009) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

TMEM16B induces chloride currents activated by calcium in mammalian cells

(2009) Simone Pifferi et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

ANO2 is the cilial calcium-activated chloride channel that may mediate olfactory amplification

(2009) Aaron B. Stephan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE