Article
Multidisciplinary Sciences
Serenella d'Ingeo, Marcello Siniscalchi, Valeria Straziota, Gianluca Ventriglia, Raffaella Sasso, Angelo Quaranta
Summary: Recent studies show that cats are sensitive to human emotional odours, particularly fear odours, and can regulate their behavior accordingly. These findings also provide the first evidence of lateralized emotional functions of olfactory pathways in cats.
SCIENTIFIC REPORTS
(2023)
Article
Agriculture, Dairy & Animal Science
Minori Arahori, Ayano Kimura, Saho Takagi, Hitomi Chijiiwa, Kazuo Fujita, Hika Kuroshima
Summary: Research found that observing human behavior does not enable cats to solve problems more effectively or change their behavior. Other than learning ability, cats' biological characteristics and experimental context may contribute to these negative results.
Article
Agriculture, Dairy & Animal Science
Maria Aires Pereira, Carmen Nobrega, Teresa L. L. Mateus, Daniela Almeida, Andreia Oliveira, Catarina Coelho, Rita Cruz, Paula Oliveira, Ana Faustino-Rocha, Maria J. J. Pires, Joao R. Mesquita, Helena Vala
Summary: This study investigated the presence of antibodies against T. gondii and N. caninum in client-owned cats from Portugal and identified risk factors. The overall seroprevalences of anti-T. gondii and anti-N. caninum were 13.1% and 3.8%, respectively. Indoor lifestyle was identified as a significant protection factor against T. gondii infection, while the presence of a chronic disease and seropositivity to N. caninum were identified as significant risk factors to T. gondii seroprevalence. This is the first report of N. caninum seropositivity in cats from Portugal.
Article
Chemistry, Inorganic & Nuclear
Jun Pang, Lingzhang Meng, Haiting Huang, Jing Ma, Linlin He, Peng Huang
Summary: This research presents a sustainable method for synthesizing a nanocomposite of gold nanoparticle-decorated hydroxymethylated lignin (HL) functionalized Fe3O4 (Fe3O4@HL/Au NPs). The material was characterized using various analytical techniques, and showed excellent catalytic activity in the formylation reaction of aminoarenes. The nanocomposite could be easily separated and reused without loss of catalytic activity. Moreover, in vivo experiments suggested that the Fe3O4@HL/Au NPs nanocomposite could potentially be used as a blood homeostatic and nephroprotective agent, with significant protective effects on blood profile and anti-inflammatory properties.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Agriculture, Dairy & Animal Science
Tom Schipper, Goedele Storms, Gerlinde Janssens, Sabine Schoofs, Eveline Capiau, Dieter Verdonck, Pascale Smets, Luc J. Peelman, Bart J. G. Broeckx
Summary: In this study, the influence of genetics on the development of corneal sequestrum in Persian, Himalayan and exotic cats was investigated. The results showed that some dams had a higher risk of producing kittens with corneal sequestrum, indicating the involvement of genetics in the disease. The heritability of the disease was high, suggesting selective breeding as a way to reduce the prevalence of the condition. However, no specific DNA region was found to be associated with the disease, suggesting the involvement of multiple genes.
Review
Agriculture, Dairy & Animal Science
Iosif Vasiu, Roman Dabrowski, Marco Wochnik, Anna Plusa, Asta Tvarijonaviciute
Summary: Mastitis is a rare condition in female cats, usually caused by bacterial agents and commonly encountered in feline mammary fibroepithelial hyperplasia (FEH). If left untreated, it can endanger both the queen and her kittens. Reliable and quick diagnosis is crucial for successful treatment. This review aims to improve current clinical evaluation and treatment plans by presenting existing knowledge on mammary gland inflammations in cats.
ANIMAL REPRODUCTION SCIENCE
(2023)
Article
Veterinary Sciences
Sarah M. L. Tan, Sarah Jajou, Anastasia C. Stellato, Lee Niel
Summary: This study explored the attitudes and practices of cat owners in Canada and the United States towards outdoor access, and found associations between provision of uncontrolled outdoor access and factors related to cat characteristics, home environment, owner perspectives, and demographics. There is a need to increase education about precautionary measures to protect the welfare of outdoor cats.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Biochemical Research Methods
Renato Simoes Moreira, Nathalia Anderson Calomeno, Gabriella Bassi das Neves, Luiz Flavio Nepomuceno do Nascimento, Vilmar Benetti Filho, Glauber Wagner, Luiz Claudio Miletti
Summary: This study aims to analyze in vitro secreted proteins from T. evansi and identify potential treatment and diagnostic biomarkers for surra diagnosis.
JOURNAL OF PROTEOMICS
(2023)
Article
Immunology
Deivys Leandro Portuondo, Alexander Batista-Duharte, Constanza Cardenas, Carlos S. de Oliveira, Julio Cesar Borges, Damiana Tellez-Martinez, Paula Andrea Santana, Adriana Gauna, Luis Mercado, Bruna Mateus de Castilho, Paulo Costa, Fanny Guzman, Iracilda Zeppone Carlos
Summary: This study identified and validated six low-sequence-identity peptides from SsEno, which exhibit B-cell epitopes and react strongly with serum from infected mice and cats with sporotrichosis. Immunization with a peptide mixture induced high levels of protective antibodies in mice and elicited a cytokine profile associated with protection against sporotrichosis. These peptides could be potential safe antigens for developing vaccine strategies against feline sporotrichosis.
MICROBIAL PATHOGENESIS
(2022)
Review
Biology
Yelena Ginzburg, Xuili An, Stefano Rivella, Adam Goldfarb
Summary: Erythroblasts undergo differentiation to become mature red blood cells, requiring large amounts of iron for hemoglobin synthesis. Recent evidence reveals the regulation of iron availability by erythroblasts and the effects of insufficient or excess iron on erythroid lineage proliferation and differentiation. Dysregulated iron metabolism is found in various congenital and acquired diseases. Understanding this mechanism provides opportunities to improve the management of patients with disordered erythropoiesis.
Article
Veterinary Sciences
Hongzao Yang, Jie Zhu, Hongyuan Guo, Aoxing Tang, Shaoyu Chen, Da Zhang, Ligang Yuan, Guangqing Liu
Summary: This study identified a host protein C11orf96 that was significantly upregulated after viral infection. The coding sequence of C11orf96 gene is relatively conserved in different mammals, rich in Ser, and has multiple predicted phosphorylation sites. The protein is strictly distributed in the cytoplasm and shows highest expression levels in the kidney.
BMC VETERINARY RESEARCH
(2022)
Article
Genetics & Heredity
Olga Amelkina, Andreia M. da Silva, Alexandre R. Silva, Pierre Comizzoli
Summary: This study aimed to analyze miRNAs in ovarian and testicular tissues of domestic cats, with a focus on their potential involvement in gonadal function, testis development, and cellular stress response. By sequencing miRNAs, the researchers identified miRNA precursors expressed in cat gonads and discovered novel candidate precursors. They also found associations between miRNAs and mRNAs, highlighting their potential role in testicular development and spermatogenesis.
FRONTIERS IN GENETICS
(2022)
Article
Veterinary Sciences
Isabel Hernandez, Jessica J. Hayward, Jeff A. Brockman, Michelle E. White, Lara Mouttham, Elizabeth A. Wilcox, Susan Garrison, Marta G. Castelhano, John P. Loftus, Filipe Espinheira Gomes, Cheryl Balkman, Marjory B. Brooks, Nadine Fiani, Marnin Forman, Tom Kern, Bruce Kornreich, Eric C. Ledbetter, Santiago Peralta, Angela M. Struble, Lisa Caligiuri, Elizabeth Corey, Lin Lin, Julie Jordan, Danny Sack, Adam R. Boyko, Leslie A. Lyons, Rory J. Todhunter
Summary: The current feline genotyping array has been beneficial for mapping within breeds and identifying variants associated with Mendelian traits in purebred cats. However, studies of complex diseases involving random bred cats require a denser genotyping array and larger sample sizes for statistically significant associations. The multi-breed study identified significant genome-wide associations with hyperthyroidism, diabetes mellitus, and eosinophilic keratoconjunctivitis, providing genomic locations for variant discovery and candidate gene screening for these diseases.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Bertrand L. Deputte, Estelle Jumelet, Caroline Gilbert, Emmanuelle Titeux
Summary: Communication between cats involves specific visual signals, with ear position being the best predictor of outcomes in cat-cat interactions. Tail position plays a less significant role in cat interactions, but is important in interactions with humans, where cats often approach with their tail up. Understanding these visual signals is crucial in promoting the welfare of cats.
Article
Veterinary Sciences
Francesca Schiaffino, Cusi Ferradas, Luis M. Jara, Guillermo Salvatierra, Alejandra Davila-Barclay, Camila Sanchez-Carrion, Alexandra Ulloa, Lucero Mascaro, Monica J. Pajuelo, Luis Guevara Sarmiento, Manolo Fernandez, Mirko Zimic
Summary: This study reports the first evidence of SARS-CoV-2 Lambda variant in symptomatic domestic cats whose owners were diagnosed with COVID-19 in Lima, Peru, suggesting potential transmission of the virus among domestic cats. Further epidemiological studies are needed to characterize the role of domestic animals in the transmission dynamics of SARS-CoV-2.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Mycology
E. S. Loreto, J. S. M. Tondolo, F. P. K. de Jesus, A. M. Engelmann, C. M. de Andrade, J. M. Santurio, R. A. Zanette, G. D. Kommers, T. M. Silva, S. H. Alves
JOURNAL DE MYCOLOGIE MEDICALE
(2020)
Article
Dermatology
Carla Weiblen, Lizandra Jaqueline Robe, Maria Isabel de Azevedo, Lara Baccarin Ianiski, Paula Cristina Stibbe, Tatiana Correa Ribeiro, Regis Adriel Zanette, Daniela Isabel Brayer Pereira, Janio Morais Santurio, Sonia de Avila Botton
Article
Infectious Diseases
Daiane Flores Dalla Lana, Tais Fernanda Andrzejewski Kaminski, Stefania Neiva Lavorato, Simone Merkel, Regis Adriel Zanette, Priscila Dalle da Rosa, Keli Jaqueline Staudt, Bibiana Verlindo de Araujo, Barbara Costa, Priscilla Maciel Quatrin, Luana Candice Genz Bazana, Felipe Alves Ferreira, Cassia Ferreira Braz Caurio, Saulo Fernandes de Andrade, Ricardo Jose Alves, Alexandre Meneghello Fuentefria
Article
Biotechnology & Applied Microbiology
B. Pippi, A. R. Joaquim, S. Merkel, R. A. Zanette, M. E. M. Nunes, D. G. da Costa Silva, L. E. Schimith, M. L. Teixeira, J. L. Franco, S. Fernandes de Andrade, A. M. Fuentefria
Summary: The study evaluated the antifungal activity and toxicology parameters of 8-hydroxyquinoline derivatives PH151 and PH153 using alternative animal models. The compounds showed potential for treating systemic candidiasis with low toxicity and were suitable for further development as new drug candidates.
JOURNAL OF APPLIED MICROBIOLOGY
(2021)
Article
Infectious Diseases
Alessandra Helena da Silva Hellwig, Danielle Machado Pagani, Iasmin da Silva Rios, Amanda Carvalho Ribeiro, Regis A. Zanette, Maria Lucia Scroferneker
Summary: The growth of S. brasiliensis isolates was more affected by iron availability compared to S. schenckii, while both fungal species conidia became more prone to oxidative stress when exposed to iron in culture medium. However, the combination of itraconazole and deferasirox only resulted in synergism against a minority of S. schenckii isolates.
Article
Microbiology
Alexandre Ehrhardt, Jessica Zolim Andreatto Mandelli, Vanessa Bergamo, William Lopes, Ricardo Keitel Donato, Regis A. Zanette, Alexandre Meneghello Fuentefria
Summary: Researchers successfully developed a new biomaterial with antifungal biofilm activity by modifying a commercially available glass ionomer cement with a specific component. The modified cement showed strong antibiofilm activity against multiple drug-resistant Candida species, while maintaining its original micromechanical and hypoallergenic properties, making it a promising candidate for dental applications.
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2021)
Review
Agronomy
Lara Baccarin Ianiski, Fernando de Souza Rodrigues, Paula Cristina Stibbe, Carla Weiblen, Daniela Isabel Brayer Pereira, Janio Morais Santurio, Cristiane de Bona da Silva, Luis Antonio Sangioni, Fernanda Silveira Flores Vogel, Mateus Matiuzzi da Costa, Valeria Dutra, Luciano Nakazato, Sonia de Avila Botton
Summary: This article primarily discusses the applicability of nanotechnology in veterinary medicine and its research in Brazil. The use of nanotechnology in veterinary medicine is still limited, but it has potential in disease treatment and diagnosis. Therefore, research and investment in nanotechnology are expected to promote its development in Brazil.
Article
Biotechnology & Applied Microbiology
P. C. Stibbe, L. B. Ianiski, C. Weiblen, A. F. Maciel, M. L. Machado, T. L. da Silveira, F. A. A. Soares, J. M. Santurio, M. P. Soares, D. I. B. Pereira, L. A. Sangioni, S. de Avila Botton
Summary: The objective of this study was to evaluate the inhibitory effects and toxicity of agricultural fungicides mefenoxam and pyraclostrobin against Pythium insidiosum. The results showed that both compounds had inhibitory effects on the pathogenic oomycete without causing toxicity in vitro and in vivo models. Further studies on pharmacokinetics, toxicity, and pharmacological interactions are necessary for evaluating their potential use in the clinical management of pythiosis.
LETTERS IN APPLIED MICROBIOLOGY
(2022)
Review
Agronomy
Lara Baccarin Ianiski, Aline Fontanella Maciel, Caroline Quintana Braga, Carla Weiblen, Daniela Isabel Brayer Pereira, Luis Antonio Sangioni, Janio Morais Santurio, Luciana Potter, Sonia de Avila Botton
Summary: This study evaluated the use of nanotechnology in the treatment of Pythium insidiosum infections and found that nanotechnology can be a promising alternative for developing antimicrobial compounds with anti-P. insidiosum activity.
Review
Parasitology
Beni Jequicene Mussengue Chauque, Thaisla Cristiane Borella da Silva, Denise Leal dos Santos, Guilherme Brittes Benitez, Leosvilda Gomes Henriques Chauque, Antonio Domingues Benetti, Regis Adriel Zanette, Marilise Brittes Rott
Summary: The ubiquitous free-living amoebae (FLA) are microorganisms of significant medical, sanitary, and ecological importance. However, their characterization within solid matrices such as soil, dust, sediment, mud, sludge, and compost remain to be systematized. In this study, a systematic review with meta-analysis was conducted to explore the global distribution of FLA in solid matrices. The analysis of 104 out of 4,414 scientific articles revealed that FLA prevalence in solid matrices was 55.13% globally. Soil had the highest prevalence (72.40%), followed by sediment (57.91%), mud (52.90%), dust (48.60%), and sewage sludge (40.19%). Acanthamoeba spp. (52.23%) and Hartmanella/Vermamoeba spp. (36.06%) were the most prevalent FLA species.
Article
Dermatology
Barbara da Costa, Bruna Pippi, Simone Merkel, Giovanna Agostinetto, Regis A. Zanette, Alexandre M. Fuentefria
Summary: This study validates Drosophila melanogaster flies as a suitable model to study dermatophytic infections. It shows that wild-type flies are resistant to infection, while Toll-deficient flies are susceptible. Antifungal drugs can protect flies from infection, except for one specific fungus.
Article
Veterinary Sciences
Diorges H. Setim, Carlos Bondan, Caroline C. Cortese, Jessica C. Peretti, Fernanda L. Facioli, Ricardo Zanella, Marcio M. Costa, Adriana C. da Motta
Summary: This study aimed to verify the presence of bovine paratuberculosis in commercial dairy herds in different mesoregions of RS, Brazil. Indirect ELISA tests and PCR were performed on milk and fecal samples, respectively. The results indicated that paratuberculosis is likely endemic in the northwest and northeast mesoregions.
PESQUISA VETERINARIA BRASILEIRA
(2023)
Article
Veterinary Sciences
J. H. Silva, L. V. Q. Contreras, C. F. Ponath, C. Bondan, M. C. Machado, F. Gonzalez
Summary: The study aimed to investigate the impact of pre and postpartum DCAD on serum calcium, phosphorus, and magnesium levels in peripartum Holstein cows. Blood samples were collected from 56 cows (18 primiparous and 38 multiparous) on different days relative to parturition to analyze mineral levels, while diet and urine samples were also collected. Prepartum DCAD showed a positive correlation with total and corrected calcium levels at day-7, and a negative correlation with magnesium levels at day-7. However, prepartum DCAD did not significantly affect phosphorus levels. Postpartum DCAD did not have any correlation with serum mineral levels. The study highlights the importance of considering parity and time period when evaluating mineral levels in Holstein cows during the transition period.
ARQUIVO BRASILEIRO DE MEDICINA VETERINARIA E ZOOTECNIA
(2023)
Article
Biotechnology & Applied Microbiology
Bruna Pippi, Regis A. Zanette, Angelica R. Joaquim, Maria E. Krummenauer, Simone Merkel, Paula Reginatto, Marilene H. Vainstein, Saulo F. Andrade, Alexandre M. Fuentefria, Juliana S. M. Tondolo, Erico S. Loreto, Janio M. Santurio
Summary: This study evaluates the antimicrobial activity of three 8-hydroxyquinoline derivatives against Pythium insidiosum and determines their pharmacodynamic characteristics. Results show that Clioquinol, PH151, and PH153 are active against all isolates, with MIC values ranging from 0.25 to 2 μg/mL. They also exhibit a time- and dose-dependent antimicrobial effect, damaging the P. insidiosum cell wall. These findings reinforce the potential of 8-hydroxyquinoline derivatives as new drugs for treating pythiosis.
JOURNAL OF APPLIED MICROBIOLOGY
(2023)
Article
Agriculture, Multidisciplinary
Andrielli Trentim Pereira, Ana Paula Maurique Pereira, Inazio Manassi Conceicao da Brandolt, Ricardo Pozzobon, Marcio Machado Costae, Bruno Leite dos Anjos, Saulo Pavarini
SEMINA-CIENCIAS AGRARIAS
(2020)