Letter
Medicine, General & Internal
Pei-Heng Kao, Li-Chuan Hsu
Summary: The study shows that patients treated with finerenone have a lower incidence of hospitalization for heart failure. However, additional factors such as medication therapy need to be considered in the study.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Review
Nutrition & Dietetics
Shinya Nakatani, Katsuhito Mori, Tetsuo Shoji, Masanori Emoto
Summary: Zinc deficiency is common in CKD patients and linked to cardiovascular disease risk factors. Zinc can protect against phosphate-induced arterial calcification by suppressing activation of nuclear factor, while higher dietary zinc intake is associated with lower risk of abdominal aortic calcification.
Article
Oncology
Yen-Cheng Chen, Liang-Tsai Yeh, Shun-Fa Yang, Ming-Chih Chou, Jing-Yang Huang, Chao-Bin Yeh
Summary: We evaluated the risk of thromboembolic events and major adverse cardiovascular events (MACEs) associated with anti-VEGF therapy in colorectal cancer patients using real-world evidence. Our study found no significant increase in the risk of thromboembolic events and MACEs in patients with advanced colorectal cancer who received anti-VEGF therapy compared to those without anti-VEGF therapy in Taiwan. This study provides real-world evidence on the safety of anti-VEGF therapy in Asian patients with advanced colorectal cancer.
Article
Cardiac & Cardiovascular Systems
Yan Gao, Mengxiao Liu, Zhiguo Ju, Haipeng Wang, Hui Gu, Ximing Wang
Summary: This study found that LV entropy can predict MACEs in LVNC patients and provide incremental prognostic value on top of LVEF and LGE. Additionally, LV entropy may help risk stratification in LGE-negative LVNC patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Urology & Nephrology
Min Li, Li-qiong Jiang, Meng-yu Zhang, Shu-su Liu, Rejean-Ruiel Regis Sawh, Jing Zheng, Yu Yan, Shi-mei Hou, Ke-qi Lu, Obadele Thorne, Bi-cheng Liu, Qing Qian, Yan-feng Wu, Min Yang, Bin Wang
Summary: This study explored the relationship and predictive value of serum fibroblast growth factor 21 (FGF21) with all-cause mortality, major adverse cardiovascular events (MACEs), and pneumonia in hemodialysis (HD) patients. The results showed that higher serum FGF21 levels were independent predictors of all-cause mortality, MACEs, and pneumonia in HD patients.
Article
Biology
Ana Cerqueira, Janete Quelhas-Santos, Ines Ferreira, Susana Sampaio, Miguel Relvas, Nidia Marques, Claudia Camila Dias, Manuel Pestana
Summary: The study evaluated the relationship between renalase serum levels and cardiovascular and renal outcomes, finding an association between renalase levels and CKD progression, hospitalizations, and mortality. This suggests that renalase may serve as a potential predictor of outcomes in pre-dialysis CKD patients.
Article
Clinical Neurology
Jason D. Hinman, Fanny Elahi, Davis Chong, Hannah Radabaugh, Adam Ferguson, Pauline Maillard, Jeffrey F. Thompson, Gary A. Rosenberg, Abhay Sagare, Abhay Moghekar, Hanzhang Lu, Tiffany Lee, Donna Wilcock, Claudia L. Satizabal, Russell Tracy, Sudha Seshadri, Kristin Schwab, Karl Helmer, Herpreet Singh, Pia Kivisakk, Steve Greenberg, Charlie DeCarli, Joel Kramer
Summary: This study found that plasma PlGF levels are associated with cognitive impairment and white matter injury, and can serve as a stable and reliable diagnostic biomarker.
ALZHEIMERS & DEMENTIA
(2023)
Article
Cardiac & Cardiovascular Systems
Susanne Schulz, Stefan Reichert, Julia Grollmitz, Lisa Friebe, Michael Kohnert, Britt Hofmann, Hans-Guenter Schaller, Frank Klawonn, Ruibing Shi
Summary: This study assessed differences in complex subgingival bacterial composition based on cardiovascular (CV) outcome in patients undergoing CABG. A subgingival biomarker from the Saccharibacteria phylum was identified to be associated with the incidence of a secondary CV event.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Urology & Nephrology
Claudia Sommerer, Sandra Mueller-Krebs, Jennifer Nadal, Ulla T. Schultheiss, Nele Friedrich, Matthias Nauck, Matthias Schmid, Christian Nusshag, Jochen Reiser, Kai-Uwe Eckardt, Martin Zeier, Salim S. Hayek
Summary: In patients with chronic kidney disease (CKD), suPAR levels are associated with mortality and cardiovascular outcomes independently of kidney function, indicating its independent role in the pathogenesis of atherosclerosis.
KIDNEY INTERNATIONAL REPORTS
(2023)
Review
Endocrinology & Metabolism
Marcus Vinicius Bolivar Malachias, Magnus Olof Wijkman, Marcello Casaccia Bertoluci
Summary: Existing risk prediction scores may be inaccurate in patients with Type 2 Diabetes Mellitus (T2DM), but measurement of natriuretic peptides, particularly NT-proBNP, can be an effective tool for risk stratification. NT-proBNP improves outcome prediction and has similar or even superior ability compared to multivariate risk models in predicting death and cardiovascular events in individuals with T2DM.
DIABETOLOGY & METABOLIC SYNDROME
(2022)
Article
Medicine, General & Internal
Katsuhiro Ono, Sadahiko Uchimoto, Masamune Miyazaki, Natsuki Honda, Katsuhito Mori, Tomoaki Morioka, Takumi Imai, Tetsuo Shoji, Masanori Emoto
Summary: This study revealed that complete right bundle branch block (CRBBB) in patients with type 2 diabetes mellitus (T2DM) was associated with an increased risk of cardiovascular events.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Diana Jalal, Bridget Sanford, Brandon Renner, Patrick Ten Eyck, Jennifer Laskowski, James Cooper, Mingyao Sun, Yousef Zakharia, Douglas Spitz, Ayotunde Dokun, Massimo Attanasio, Kenneth Jones, Joshua M. Thurman
Summary: The study found that pathways of angiogenesis and inflammation were activated in the plasma and EVs of both native and post-transplant CKD patients, indicating similar mechanisms of CVD may be present in these two groups.
SCIENTIFIC REPORTS
(2021)
Article
Cardiac & Cardiovascular Systems
Rafael Escate, Teresa Padro, Rosa Suades, Sandra Camino, Ovidio Muniz, Jose Luis Diaz-Diaz, Alessandro Sionis, Pedro Mata, Lina Badimon
Summary: The study investigated the predictive role of miRNAs in atherosclerotic plaque progression and clinical event presentation in FH patients, identifying miR-133a as the best predictor for CVE.
CARDIOVASCULAR RESEARCH
(2021)
Article
Cardiac & Cardiovascular Systems
Albert Topf, Moritz Mirna, Nina Bacher, Vera Paar, Christoph Edlinger, Lukas J. Motloch, Sarah Gharibeh, Marwin Bannehr, Uta C. Hoppe, Michael Lichtenauer
Summary: The study found that fetuin-A may be a promising marker for predicting short-term adverse cardiac events in TTC patients. Other biomarkers failed to show a prognostic impact.
JOURNAL OF CARDIOVASCULAR DEVELOPMENT AND DISEASE
(2021)
Article
Oncology
Tomoyuki Naito, Yuji Minegishi, Hideaki Shiraishi, Tatsuhiko Hoshino, Junichi Maeda, Toshiya Yokota, Shingo Ikeda, Miyanaga Akihiko, Masahiro Seike
Summary: The study explores the impact of background cardiovascular risk factors on VEGF inhibitor-related adverse vascular events (AVEs) in NSCLC patients. It found that male gender, smoking history, hypertension, dyslipidemia, diabetes, and cardiovascular disease were associated with increased risk of VEGF-related AVEs. Hypertension and chronic kidney disease were associated with discontinuation due to VEGF-related AVEs. The study recommends caution in using VEGF inhibitors for patients with ≥3 cardiovascular risk factors.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2023)
Article
Urology & Nephrology
Masaru Matsui, Ken-ichi Samejima, Yukiji Takeda, Kaoru Tanabe, Katsuhiko Morimoto, Keisuke Okamoto, Miho Tagawa, Kenji Onoue, Satoshi Okayama, Hiroyuki Kawata, Rika Kawakami, Yasuhiro Akai, Yoshihiko Saito
AMERICAN JOURNAL OF NEPHROLOGY
(2015)
Article
Cardiac & Cardiovascular Systems
Masaru Matsui, Ken-ichi Samejima, Yukiji Takeda, Katsuhiko Morinnoto, Miho Tagawa, Kenji Onoue, Satoshi Okayama, Hiroyuki Kawata, Rika Kawakami, Yasuhiro Akai, Hiroyuki Okura, Yoshihiko Saito
CARDIORENAL MEDICINE
(2016)
Article
Hematology
Masaru Matsui, Yasuhiro Akai, Ken-ichi Samejima, Hideo Tsushima, Kaori Tanabe, Katsuhiko Morimoto, Miho Tagawa, Yoshihiko Saito
THERAPEUTIC APHERESIS AND DIALYSIS
(2017)
Article
Cardiac & Cardiovascular Systems
Tomoya Ueda, Rika Kawakami, Yasuki Nakada, Tomoya Nakano, Hitoshi Nakagawa, Masaru Matsui, Taku Nishida, Kenji Onoue, Tsunenari Soeda, Satoshi Okayama, Makoto Watanabe, Hiroyuki Okura, Yoshihiko Saito
Article
Endocrinology & Metabolism
K. Morimoto, M. Matsui, K. Samejima, T. Kanki, M. Nishimoto, K. Tanabe, M. Murashima, M. Eriguchi, Y. Akai, M. Iwano, H. Shiiki, H. Yamada, M. Kanauchi, K. Dohi, K. Tsuruya, Y. Saito
Article
Pathology
Hiroe Itami, Shigeo Hara, Kenichi Samejima, Hideo Tsushima, Katsuhiko Morimoto, Keisuke Okamoto, Takaaki Kosugi, Takahiro Kawano, Kengo Fujiki, Hiromichi Kitada, Kinta Hatakeyama, Kazuhiko Tsuruya, Chiho Ohbayashi
Article
Urology & Nephrology
Kaori Tanabe, Ken-Ichi Samejima, Fumihiro Fukata, Takaaki Kosugi, Hideo Tsushima, Katsuhiko Morimoto, Keisuke Okamoto, Masaru Matsui, Masahiro Eriguchi, Naoki Maruyama, Yasuhiro Akai, Kazuhiko Tsuruya
Summary: In this multicenter cohort study, the initial PSL dose for initial treatment of MCD was not found to be significantly associated with time to remission, remission rate, time to relapse, or relapse rate. Therefore, a low initial steroid dose may be sufficient to achieve remission in MCD patients.
CLINICAL AND EXPERIMENTAL NEPHROLOGY
(2022)
Article
Transplantation
Masatoshi Nishimoto, Miho Murashima, Maiko Kokubu, Masaru Matsui, Masahiro Eriguchi, Ken-Ichi Samejima, Yasuhiro Akai, Kazuhiko Tsuruya
Summary: The relationship between kidney function at 3 months after acute kidney injury (AKI) and kidney function prognosis was examined in this study. The study found that AKI patients had a faster decline in estimated glomerular filtration rate (eGFR) after 3 months postoperatively and were associated with incident chronic kidney disease (CKD) and a decline in eGFR >= 30%. The findings suggest the importance of evaluating kidney function beyond 3 months after surgery or using other indicators such as cystatin C values.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Urology & Nephrology
Masatoshi Nishimoto, Miho Murashima, Maiko Kokubu, Masaru Matsui, Masahiro Eriguchi, Ken-Ichi Samejima, Yasuhiro Akai, Kazuhiko Tsuruya
Summary: The study found that AKI is strongly associated with lower hematocrit values postoperatively, and higher stages or longer duration of AKI are correlated with more severe anemia. Higher mortality rates at 3 months postoperatively were associated with AKI, and this mortality may be partially mediated by anemia following AKI, based on mediation analysis. Further research is needed to determine whether correcting anemia following AKI can improve mortality rates.
CLINICAL KIDNEY JOURNAL
(2021)
Article
Multidisciplinary Sciences
Maiko Kokubu, Masaru Matsui, Takayuki Uemura, Katsuhiko Morimoto, Masahiro Eriguchi, Kenichi Samejima, Yasuhiro Akai, Kazuhiko Tsuruya
SCIENTIFIC REPORTS
(2020)
Article
Endocrinology & Metabolism
Sadanori Okada, Ken-ichi Samejima, Masaru Matsui, Katsuhiko Morimoto, Riri Furuyama, Kaori Tanabe, Masahiro Eriguchi, Yasuhiro Akai, Yoshihiko Saito, Kazuhiko Tsuruya
BMJ OPEN DIABETES RESEARCH & CARE
(2020)
Article
Urology & Nephrology
Katsuhiko Morimoto, Yasuhiro Akai, Masaru Matsui, Hiroki Yano, Miho Tagawa, Ken-ichi Samejima, Yoshihiko Saito
Article
Urology & Nephrology
Katsuhiko Morimoto, Kimihiko Nakatani, Osamu Asai, Kuniko Mondori, Kiyonori Tomiwa, Takamitsu Mondori, Yoshiyuki Nakagawa, Masayuki Iwano, Hideo Shiiki