Cyclic mechanical stress downregulates endothelin-1 and its responsive genes independently of TGFβ1 in dermal fibroblasts

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

The transcriptional regulator megakaryoblastic leukemia-1 mediates serum response factor-independent activation of tenascin-C transcription by mechanical stress

(2011) Maria B. Asparuhova et al.   FASEB JOURNAL

Mechanical Tension Increases CCN2/CTGF Expression and Proliferation in Gingival Fibroblasts via a TGFβ-Dependent Mechanism

(2011) Fen Guo et al.   PLoS One

Cell Motility and Mechanics in Three-Dimensional Collagen Matrices

(2010) Frederick Grinnell et al.   Annual Review of Cell and Developmental Biology

Endothelin 1 contributes to the effect of transforming growth factor β1 on wound repair and skin fibrosis

(2010) David Lagares et al.   ARTHRITIS AND RHEUMATISM

Cyclic mechanical stretch reduces myofibroblast differentiation of primary lung fibroblasts

(2010) Marjolein E. Blaauboer et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Transcapillary exchange: role and importance of the interstitial fluid pressure and the extracellular matrix

(2010) Rolf K. Reed et al.   CARDIOVASCULAR RESEARCH

Induction of matrix metalloproteinase-1 by small interfering RNA targeting connective tissue growth factor in dermal fibroblasts from patients with systemic sclerosis

(2010) Hirohisa Ishibuchi et al.   EXPERIMENTAL DERMATOLOGY

Akt inhibition up-regulates MMP1 through a CCN2-dependent pathway in human dermal fibroblasts

(2010) Andreea M. Bujor et al.   EXPERIMENTAL DERMATOLOGY

Defective granulation tissue formation in mice with specific ablation of integrin-linked kinase in fibroblasts - role of TGF 1 levels and RhoA activity

(2010) K. Blumbach et al.   JOURNAL OF CELL SCIENCE

Integrins and Extracellular Matrix in Mechanotransduction

(2010) M. A. Schwartz   Cold Spring Harbor Perspectives in Biology

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

Cyclical Cell Stretching of Skin-Derived Fibroblasts Downregulates Connective Tissue Growth Factor (CTGF) Production

(2009) Yuichiro Kanazawa et al.   CONNECTIVE TISSUE RESEARCH

Scleroderma

(2009) Armando Gabrielli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

(2009) Andrew Leask et al.   Journal of Cell Communication and Signaling

Looking Older

(2008) Gary J. Fisher et al.   ARCHIVES OF DERMATOLOGY

Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts

(2008) Alfiya Akhmetshina et al.   ARTHRITIS AND RHEUMATISM