Insight into newly discovered innate immune modulation in atopic dermatitis

Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis

(2014) E. Guttman-Yassky et al.   JOURNAL OF IMMUNOLOGY

Innate Lymphoid Cells: Emerging Insights in Development, Lineage Relationships, and Function

(2012) Hergen Spits et al.   Annual Review of Immunology

IL-33 and ST2 in Atopic Dermatitis: Expression Profiles and Modulation by Triggering Factors

(2012) Terhi Savinko et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Transcription factor RORα is critical for nuocyte development

(2012) See Heng Wong et al.   NATURE IMMUNOLOGY

Atopic dermatitis - from new pathophysiologic insights to individualized therapy

(2011) N. Novak et al.   ALLERGY

Advances in atopic dermatitis

(2011) Natalija Novak et al.   CURRENT OPINION IN IMMUNOLOGY

Development of PLZF-expressing innate T cells

(2011) Eric S Alonzo et al.   CURRENT OPINION IN IMMUNOLOGY

Intrinsic alterations of pro-inflammatory mediators in unstimulated and TLR-2 stimulated keratinocytes from atopic dermatitis patients

(2011) Margarete Niebuhr et al.   EXPERIMENTAL DERMATOLOGY

Innate immune sensing 2.0 - from linear activation pathways to fine tuned and regulated innate immune networks

(2011) Thomas Volz et al.   EXPERIMENTAL DERMATOLOGY

Atopic dermatitis: a disease of altered skin barrier and immune dysregulation

(2011) Mark Boguniewicz et al.   IMMUNOLOGICAL REVIEWS

Understanding the roles of basophils: breaking dawn

(2011) Booki Min et al.   IMMUNOLOGY

Treatment of severe refractory adult atopic dermatitis with ustekinumab

(2011) Rafael Puya et al.   INTERNATIONAL JOURNAL OF DERMATOLOGY

Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes

(2011) Xiuju Dai et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Altered Peripheral Invariant Natural Killer T Cells in Atopic Dermatitis

(2011) Edit Gyimesi et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Invariant NKT cells are required for airway inflammation induced by environmental antigens

(2011) Gerhard Wingender et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Antimicrobial Peptides: Old Molecules with New Ideas

(2011) Teruaki Nakatsuji et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Innate Immunity: Ignored for Decades, but Not Forgotten

(2011) Robert L. Modlin   JOURNAL OF INVESTIGATIVE DERMATOLOGY

TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation

(2011) Mark C. Siracusa et al.   NATURE

Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161

(2011) Jenny M Mjösberg et al.   NATURE IMMUNOLOGY

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

(2011) Ya-Jen Chang et al.   NATURE IMMUNOLOGY

Mutual Antagonism of T Cells Causing Psoriasis and Atopic Eczema

(2011) Stefanie Eyerich et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atopic Dermatitis

(2010) Thomas Bieber   Annals of Dermatology

History of eczema herpeticum is associated with the inability to induce human β-defensin (HBD)-2, HBD-3 and cathelicidin in the skin of patients with atopic dermatitis

(2010) T.R. Hata et al.   BRITISH JOURNAL OF DERMATOLOGY

IL-17 and IL-22 in atopic allergic disease

(2010) Yuri Souwer et al.   CURRENT OPINION IN IMMUNOLOGY

Natural killer cells in atopic and autoimmune diseases of the skin

(2010) Dagmar von Bubnoff et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Thymic stromal lymphopoietin–activated invariant natural killer T cells trigger an innate allergic immune response in atopic dermatitis

(2010) Wen Hao Wu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-25 in Atopic Dermatitis: A Possible Link between Inflammation and Skin Barrier Dysfunction?

(2010) Malene Hvid et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

(2010) Daniel R. Neill et al.   NATURE

IL25 elicits a multipotent progenitor cell population that promotes TH2 cytokine responses

(2010) Steven A. Saenz et al.   NATURE

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling

(2010) Hergen Spits et al.   NATURE IMMUNOLOGY

Raising the NKT cell family

(2010) Dale I Godfrey et al.   NATURE IMMUNOLOGY

Systemically dispersed innate IL-13-expressing cells in type 2 immunity

(2010) A. E. Price et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thymic Stromal Lymphopoietin Induces Chemotactic and Prosurvival Effects in Eosinophils

(2009) Chun K. Wong et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

IL-18 skews the invariant NKT-cell population via autoreactive activation in atopic eczema

(2009) Sara M. Lind et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dysregulation of CD36 upon TLR-2 stimulation in monocytes from patients with atopic dermatitis and the TLR2 R753Q polymorphism

(2009) Margarete Niebuhr et al.   EXPERIMENTAL DERMATOLOGY

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen

(2009) Michiko K. Oyoshi et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13

(2009) Rui He et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells

(2009) Kristine E. Nograles et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Skin and Peripheral Lymph Node Invariant NKT Cells Are Mainly Retinoic Acid Receptor-Related Orphan Receptor  t+ and Respond Preferentially under Inflammatory Conditions

(2009) J.-M. Doisne et al.   JOURNAL OF IMMUNOLOGY

The IL-23/Th17 Axis in the Immunopathogenesis of Psoriasis

(2009) Antonella Di Cesare et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Innate production of TH2 cytokines by adipose tissue-associated c-Kit+Sca-1+ lymphoid cells

(2009) Kazuyo Moro et al.   NATURE

Mast cell transcriptional networks

(2008) Clifford M. Takemoto et al.   BLOOD CELLS MOLECULES AND DISEASES

K6PC-5, a novel sphingosine kinase activator, improves long-term ultraviolet light-exposed aged murine skin

(2008) Hwa-young Park et al.   EXPERIMENTAL DERMATOLOGY

IL-17 in atopic eczema: Linking allergen-specific adaptive and microbial-triggered innate immune response

(2008) Kilian Eyerich et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Ozone exposure in a mouse model induces airway hyperreactivity that requires the presence of natural killer T cells and IL-17

(2008) Muriel Pichavant et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Possible Pathogenic Role of Th17 Cells for Atopic Dermatitis

(2008) Chizuko Koga et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Antimicrobial Protein Psoriasin (S100A7) Is Upregulated in Atopic Dermatitis and after Experimental Skin Barrier Disruption

(2008) Regine Gläser et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Critical role of ROR- t in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation

(2008) M.-L. Michel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA