Patterning skin by planar cell polarity: the multi-talented hair designer

Mutations in Prickle Orthologs Cause Seizures in Flies, Mice, and Humans

(2011) Hirotaka Tao et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development

(2011) Ellen J. Ezratty et al.   CELL

Role of epidermal primary cilia in the homeostasis of skin and hair follicles

(2011) M. J. Croyle et al.   DEVELOPMENT

Vangl2 Promotes Wnt/Planar Cell Polarity-like Signaling by Antagonizing Dvl1-Mediated Feedback Inhibition in Growth Cone Guidance

(2011) Beth Shafer et al.   DEVELOPMENTAL CELL

PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube

(2011) Westley Heydeck et al.   DEVELOPMENTAL DYNAMICS

Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia

(2011) J. B. Wallingford et al.   GENES & DEVELOPMENT

Mutations in the planar cell polarity gene, Fuzzy, are associated with neural tube defects in humans

(2011) J. H. Seo et al.   HUMAN MOLECULAR GENETICS

Identification and characterization of novel rare mutations in the planar cell polarity genePRICKLE1in human neural tube defects

(2011) Ciprian M. Bosoi et al.   HUMAN MUTATION

Mitotic internalization of planar cell polarity proteins preserves tissue polarity

(2011) Danelle Devenport et al.   NATURE CELL BIOLOGY

Pointing in the right direction: new developments in the field of planar cell polarity

(2011) Roy Bayly et al.   NATURE REVIEWS GENETICS

Planar cell polarity pathway genes and risk for spina bifida

(2010) Shu Wen et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Cell Polarity in Eggs and Epithelia: Parallels and Diversity

(2010) Daniel St Johnston et al.   CELL

When whorls collide: the development of hair patterns in frizzled 6 mutant mice

(2010) Y. Wang et al.   DEVELOPMENT

PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals

(2010) Huiqing Zeng et al.   DEVELOPMENTAL BIOLOGY

Epidermal Wound Repair Is Regulated by the Planar Cell Polarity Signaling Pathway

(2010) Jacinta Caddy et al.   DEVELOPMENTAL CELL

Functional characterization of highly adherent CD34+ keratinocytes isolated from human skin

(2010) Araika Gutiérrez-Rivera et al.   EXPERIMENTAL DERMATOLOGY

Exploration of the functional hierarchy of the basal layer of human epidermis at the single-cell level using parallel clonal microcultures of keratinocytes

(2010) Nicolas O. Fortunel et al.   EXPERIMENTAL DERMATOLOGY

Fuz Controls the Morphogenesis and Differentiation of Hair Follicles through the Formation of Primary Cilia

(2010) Daisy Dai et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning

(2010) Hai Song et al.   NATURE

Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia

(2010) Boris Guirao et al.   NATURE CELL BIOLOGY

Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus

(2010) Fadel Tissir et al.   NATURE NEUROSCIENCE

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

VANGL2Mutations in Human Cranial Neural-Tube Defects

(2010) Yun-Ping Lei et al.   NEW ENGLAND JOURNAL OF MEDICINE

Activation of the planar cell polarity formin DAAM1 leads to inhibition of endothelial cell proliferation, migration, and angiogenesis

(2010) R. Ju et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Planar Cell Polarity Acts Through Septins to Control Collective Cell Movement and Ciliogenesis

(2010) Su Kyoung Kim et al.   SCIENCE

Reaction-Diffusion Model as a Framework for Understanding Biological Pattern Formation

(2010) S. Kondo et al.   SCIENCE

Directional cell migration in vivo

(2010) Carlos Carmona-Fontaine et al.   Cell Adhesion & Migration

Epidermal patterning and induction of different hair types during mouse embryonic development

(2009) Olivier Duverger et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

The Hair Follicle as a Dynamic Miniorgan

(2009) Marlon R. Schneider et al.   CURRENT BIOLOGY

The skinny on Fat: an enormous cadherin that regulates cell adhesion, tissue growth, and planar cell polarity

(2009) Richelle Sopko et al.   CURRENT OPINION IN CELL BIOLOGY

Planar cell polarity effector geneFuzzyregulates cilia formation and Hedgehog signal transduction in mouse

(2009) Westley Heydeck et al.   DEVELOPMENTAL DYNAMICS

What are melanocytesreallydoing all day long…?

(2009) P. M. Plonka et al.   EXPERIMENTAL DERMATOLOGY

Novel mutations inVANGL1in neural tube defects

(2009) Zoha Kibar et al.   HUMAN MUTATION

Pattern formation today

(2009) Cheng-Ming Chuong et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse

(2009) Aurélia Ravni et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Planar Cell Polarity and the Kidney

(2009) H. McNeill   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development

(2009) Ryan S. Gray et al.   NATURE CELL BIOLOGY

Primary cilia can both mediate and suppress Hedgehog pathway–dependent tumorigenesis

(2009) Sunny Y Wong et al.   NATURE MEDICINE

Line up and listen: Planar cell polarity regulation in the mammalian inner ear

(2009) Padmashree C.G. Rida et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Progress and challenges in understanding planar cell polarity signaling

(2009) Jeffrey D. Axelrod   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A quest for the mechanism regulating global planar cell polarity of tissues

(2009) Jun Wu et al.   TRENDS IN CELL BIOLOGY

Neuronal Polarity

(2009) S. Tahirovic et al.   Cold Spring Harbor Perspectives in Biology

The Signaling Mechanisms Underlying Cell Polarity and Chemotaxis

(2009) F. Wang   Cold Spring Harbor Perspectives in Biology

Planar Cell Polarity: Keeping Hairs Straight Is Not So Simple

(2009) H. McNeill   Cold Spring Harbor Perspectives in Biology

Widely Conserved Signaling Pathways in the Establishment of Cell Polarity

(2009) L. M. McCaffrey et al.   Cold Spring Harbor Perspectives in Biology

Remodeling Epithelial Cell Organization: Transitions Between Front-Rear and Apical-Basal Polarity

(2009) W. J. Nelson   Cold Spring Harbor Perspectives in Biology

Planar Cell Polarity Signaling: From Fly Development to Human Disease

(2008) Matias Simons et al.   Annual Review of Genetics

The Oak Ridge Polycystic Kidney mouse: Modeling ciliopathies of mice and men

(2008) Jonathan M. Lehman et al.   DEVELOPMENTAL DYNAMICS

Localization of Inv in a distinctive intraciliary compartment requires the C-terminal ninein-homolog-containing region

(2008) D. Shiba et al.   JOURNAL OF CELL SCIENCE

An Essential Role for Dermal Primary Cilia in Hair Follicle Morphogenesis

(2008) Jonathan M. Lehman et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles

(2008) Danelle Devenport et al.   NATURE CELL BIOLOGY

Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells

(2008) Tae Joo Park et al.   NATURE GENETICS

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mammalian Rho GTPases: new insights into their functions from in vivo studies

(2008) Sarah J. Heasman et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Murine Dishevelled 3 Functions in Redundant Pathways with Dishevelled 1 and 2 in Normal Cardiac Outflow Tract, Cochlea, and Neural Tube Development

(2008) S. Leah Etheridge et al.   PLoS Genetics