Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise
Published 2012 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise
Authors
Keywords
-
Journal
EXPERIMENTAL DERMATOLOGY
Volume 21, Issue 7, Pages 481-489
Publisher
Wiley
Online
2012-05-15
DOI
10.1111/j.1600-0625.2012.01534.x
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Expression of Retinoid-regulated Genes in Lamellar Ichthyosis vs. Healthy Control Epidermis: Changes after Oral Treatment with Liarozole
- (2014) E Loriè et al. ACTA DERMATO-VENEREOLOGICA
- Nanoparticles: a review of particle toxicology following inhalation exposure
- (2012) Shahnaz Bakand et al. INHALATION TOXICOLOGY
- Realm of Revertant Mosaicism Expanding
- (2012) Marcel F. Jonkman et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Applications of Nanotechnology in Dermatology
- (2012) Lisa A. DeLouise JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Gene expression analysis of an epidermolysis bullosa simplex Dowling-Meara cell line by subtractive hybridization: recapitulation of cellular differentiation, migration and wound healing
- (2011) Martin Wagner et al. EXPERIMENTAL DERMATOLOGY
- Role of a Type IV–Like Secretion System of Streptococcus suis 2 in the Development of Streptococcal Toxic Shock Syndrome
- (2011) Yan Zhao et al. JOURNAL OF INFECTIOUS DISEASES
- Chemical Chaperones Protect Epidermolysis Bullosa Simplex Keratinocytes from Heat Stress–Induced Keratin Aggregation: Involvement of Heat Shock Proteins and MAP Kinases
- (2011) Jean Christopher Chamcheu et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Keratin 14-Null Cells as a Model to Test the Efficacy of Gene Therapy Approaches in Epithelial Cells
- (2011) Mariella D'Alessandro et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Statins Downregulate K6a Promoter Activity: A Possible Therapeutic Avenue for Pachyonychia Congenita
- (2011) Yiwei Zhao et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Use of Self-Delivery siRNAs to Inhibit Gene Expression in an Organotypic Pachyonychia Congenita Model
- (2011) Robyn P. Hickerson et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- A Large Mutational Study in Pachyonychia Congenita
- (2011) Neil J. Wilson et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Phenotypic and Molecular Genetic Features of Pachyonychia Congenita
- (2011) W.H. Irwin McLean et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Novel Molecular Therapies for Heritable Skin Disorders
- (2011) Jouni Uitto et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Toxicology of Nanomaterials Used in Nanomedicine
- (2011) Jinshun Zhao et al. JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- Generation of keratinocytes from normal and recessive dystrophic epidermolysis bullosa-induced pluripotent stem cells
- (2011) M. Itoh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nanotoxicology and in vitro studies: The need of the hour
- (2011) Sumit Arora et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Development of a Bioengineered Skin-Humanized Mouse Model for Psoriasis
- (2010) Sara Guerrero-Aspizua et al. AMERICAN JOURNAL OF PATHOLOGY
- Keratin gene mutations in disorders of human skin and its appendages
- (2010) Jean Christopher Chamcheu et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Epidermolysis bullosa simplex due toKRT5mutations: mutation-related differences in cellular fragility and the protective effects of trimethylamineN-oxide in cultured primary keratinocytes
- (2010) J.C. Chamcheu et al. BRITISH JOURNAL OF DERMATOLOGY
- Botulinum toxin in the treatment of sweat-worsened foot problems in patients with epidermolysis bullosa simplex and pachyonychia congenita
- (2010) C. Swartling et al. BRITISH JOURNAL OF DERMATOLOGY
- Immortalized keratinocytes derived from patients with epidermolytic ichthyosis reproduce the disease phenotype: a usefulin vitromodel for testing new treatments
- (2010) J.C. Chamcheu et al. BRITISH JOURNAL OF DERMATOLOGY
- Keratins 2 and 4/13 in reconstituted human skin are reciprocally regulated by retinoids binding to nuclear receptor RARα
- (2010) Marie Virtanen et al. EXPERIMENTAL DERMATOLOGY
- K14 mRNA reprogramming for dominant epidermolysis bullosa simplex
- (2010) Verena Wally et al. HUMAN MOLECULAR GENETICS
- The ubiquitin ligase CHIP/STUB1 targets mutant keratins for degradation
- (2010) Stefanie Löffek et al. HUMAN MUTATION
- Skin Absorption and Potential Toxicity of Nanoparticulate Nanomaterials
- (2010) Biancamaria Baroli Journal of Biomedical Nanotechnology
- Animal Models of Epidermolysis Bullosa: Update 2010
- (2010) Leena Bruckner-Tuderman et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Development of Skin-Humanized Mouse Models of Pachyonychia Congenita
- (2010) Marta García et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Revised nomenclature and classification of inherited ichthyoses: Results of the First Ichthyosis Consensus Conference in Sorèze 2009
- (2010) Vinzenz Oji et al. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY
- Differential Modulation of Keratin Expression by Sulforaphane Occurs via Nrf2-dependent and -independent Pathways in Skin Epithelia
- (2010) Michelle Kerns et al. MOLECULAR BIOLOGY OF THE CELL
- Efficient KRT14 Targeting and Functional Characterization of Transplanted Human Keratinocytes for the Treatment of Epidermolysis Bullosa Simplex
- (2010) Lisa M Petek et al. MOLECULAR THERAPY
- Mitotic Recombination in Patients with Ichthyosis Causes Reversion of Dominant Mutations in KRT10
- (2010) K. A. Choate et al. SCIENCE
- Small Amounts of Zinc from Zinc Oxide Particles in Sunscreens Applied Outdoors Are Absorbed through Human Skin
- (2010) Brian Gulson et al. TOXICOLOGICAL SCIENCES
- Revertant mosaicism in skin: natural gene therapy
- (2010) Joey E. Lai-Cheong et al. TRENDS IN MOLECULAR MEDICINE
- Treatment of Epidermolysis Bullosa Simplex, Weber-Cockayne Type, With Botulinum Toxin Type A
- (2009) Roxanne J. Abitbol ARCHIVES OF DERMATOLOGY
- Cytokeratins 16 and 10 bind to retinoic acid covalently in skin tissue of mice
- (2009) N. Takahashi et al. BRITISH JOURNAL OF DERMATOLOGY
- Introducing Nanochemoprevention as a Novel Approach for Cancer Control: Proof of Principle with Green Tea Polyphenol Epigallocatechin-3-Gallate
- (2009) I. A. Siddiqui et al. CANCER RESEARCH
- Severe keratin 5 and 14 mutations induce down-regulation of junction proteins in keratinocytes
- (2009) Mirjana Liovic et al. EXPERIMENTAL CELL RESEARCH
- siRNA silencing of keratinocyte-specific GFP expression in a transgenic mouse skin model
- (2009) E Gonzalez-Gonzalez et al. GENE THERAPY
- Cytokines as genetic modifiers in K5���/���mice and in human epidermolysis bullosa simplex
- (2009) Wera Roth et al. HUMAN MUTATION
- Epidermolysis bullosa simplex: a paradigm for disorders of tissue fragility
- (2009) Pierre A. Coulombe et al. JOURNAL OF CLINICAL INVESTIGATION
- Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients
- (2009) Robyn P. Hickerson et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Characterization of immortalized human epidermolysis bullosa simplex (KRT5) cell lines: Trimethylamine N-oxide protects the keratin cytoskeleton against disruptive stress condition
- (2009) Jean Christopher Chamcheu et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- ERK Involvement in Resistance to Apoptosis in Keratinocytes with Mutant Keratin
- (2009) David Russell et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- First-in-human Mutation-targeted siRNA Phase Ib Trial of an Inherited Skin Disorder
- (2009) Sancy A Leachman et al. MOLECULAR THERAPY
- The chemical chaperone trimethylamine N-oxide ameliorates the effects of mutant keratins in cultured cells
- (2008) D. Lee et al. BRITISH JOURNAL OF DERMATOLOGY
- A systematic review of randomized controlled trials of treatments for inherited forms of epidermolysis bullosa
- (2008) S. M. Langan et al. CLINICAL AND EXPERIMENTAL DERMATOLOGY
- Dual-specificity phosphatases in the hypo-osmotic stress response of keratin-defective epithelial cell lines
- (2008) Mirjana Liovic et al. EXPERIMENTAL CELL RESEARCH
- A dominant vimentin mutant upregulates Hsp70 and the activity of the ubiquitin-proteasome system, and causes posterior cataracts in transgenic mice
- (2008) R. Bornheim et al. JOURNAL OF CELL SCIENCE
- Therapeutic siRNAs for dominant genetic skin disorders including pachyonychia congenita
- (2008) Sancy A. Leachman et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- Genetically engineered mouse models for skin research: Taking the next step
- (2008) Jiang Chen et al. JOURNAL OF DERMATOLOGICAL SCIENCE
- SMaRT Technology Enables Gene Expression Repair in Skin Gene Therapy
- (2008) Ulrich R. Hengge JOURNAL OF INVESTIGATIVE DERMATOLOGY
- The Human Intermediate Filament Database: comprehensive information on a gene family involved in many human diseases
- (2007) Ildiko Szeverenyi et al. HUMAN MUTATION
- Retinoic acid metabolism blocking agents (RAMBAs): a new paradigm in the treatment of hyperkeratotic disorders
- (2007) Christel J. Verfaille et al. JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT
- Development of Therapeutic siRNAs for Pachyonychia Congenita
- (2007) Frances J.D. Smith et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- 5′ Trans-Splicing Repair of the PLEC1 Gene
- (2007) Verena Wally et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Single-Nucleotide-Specific siRNA Targeting in a Dominant-Negative Skin Model
- (2007) Robyn P. Hickerson et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started