Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway

AMPK, insulin resistance, and the metabolic syndrome

(2013) Neil B. Ruderman et al.   JOURNAL OF CLINICAL INVESTIGATION

Honokiol and magnolol stimulate glucose uptake by activating PI3K-dependent Akt in L6 myotubes

(2012) Sun-Sil Choi et al.   BIOFACTORS

Honokiol ameliorates renal fibrosis by inhibiting extracellular matrix and pro-inflammatory factors in vivo and in vitro

(2011) Chih-Kang Chiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

Magnolol, a major bioactive constituent of the bark of Magnolia officinalis, exerts antiepileptic effects via the GABA/benzodiazepine receptor complex in mice

(2011) CR Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fermented garlic protects diabetic, obese mice when fed a high-fat diet by antioxidant effects

(2011) Young-Mi Jung et al.   NUTRITION RESEARCH

New insights into the role of macrophages in adipose tissue inflammation and fatty liver disease: modulation by endogenous omega-3 fatty acid-derived lipid mediators

(2011) Joan Clària   Frontiers in Immunology

Hepatic steatosis: a role for de novo lipogenesis and the transcription factor SREBP-1c

(2010) P. Ferré et al.   DIABETES OBESITY & METABOLISM

Molecular therapy for obesity and diabetes based on a long-term increase in hepatic fatty-acid oxidation

(2010) Josep M. Orellana-Gavaldà et al.   HEPATOLOGY

Fatty liver disease in children: eat now pay later

(2010) Ruth M. L. De Bruyne et al.   Hepatology International

Anti-Inflammatory Bioactivities of Honokiol through Inhibition of Protein Kinase C, Mitogen-Activated Protein Kinase, and the NF-κB Pathway To Reduce LPS-Induced TNFα and NO Expression

(2010) Louis Kuoping Chao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A Mouse Model of Metabolic Syndrome: Insulin Resistance, Fatty Liver and Non-Alcoholic Fatty Pancreas Disease (NAFPD) in C57BL/6 Mice Fed a High Fat Diet

(2010) Julio C. Fraulob et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Anti-Inflammatory Effects of the Neurotransmitter Agonist Honokiol in a Mouse Model of Allergic Asthma

(2010) M. E. Munroe et al.   JOURNAL OF IMMUNOLOGY

Neuroprotective effect of honokiol and magnolol, compounds from Magnolia officinalis, on beta-amyloid-induced toxicity in PC12 cells

(2010) Chu Peng Hoi et al.   PHYTOTHERAPY RESEARCH

Antioxidative and hepatoprotective effects of magnolol on acetaminophen-induced liver damage in rats

(2009) Yung-Hsiang Chen et al.   ARCHIVES OF PHARMACAL RESEARCH

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

Role of adenosine monophosphate-activated protein kinase-p70 ribosomal S6 kinase-1 pathway in repression of liver X receptor-alpha-dependent lipogenic gene induction and hepatic steatosis by a novel class of dithiolethiones

(2009) Seong Hwan Hwahng et al.   HEPATOLOGY

Magnolia officinalis Reverses Alcoholic Fatty Liver by Inhibiting the Maturation of Sterol Regulatory Element–Binding Protein-1c

(2009) Hu-Quan Yin et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Honokiol reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element binding protein-1c and the expression of its downstream lipogenesis genes

(2009) Hu-Quan Yin et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Alpha-lipoic acid decreases hepatic lipogenesis through adenosine monophosphate-activated protein kinase (AMPK)-dependent and AMPK-independent pathways

(2008) Keun-Gyu Park et al.   HEPATOLOGY

Fatty Liver

(2007) Anna Kotronen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY