Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner

Rottlerin enhances IL-1β-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells

(2012) Eun Jung Park et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity

(2011) Tsui-Ting Ching et al.   AGING CELL

Caveolin-1, cellular senescence and age-related diseases

(2011) Huafei Zou et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2

(2011) Traci R Lyons et al.   NATURE MEDICINE

Age Related Changes in NAD+ Metabolism Oxidative Stress and Sirt1 Activity in Wistar Rats

(2011) Nady Braidy et al.   PLoS One

DNA damage response and cellular senescence in tissues of aging mice

(2009) Chunfang Wang et al.   AGING CELL

Collagen Structure and Stability

(2009) Matthew D. Shoulders et al.   Annual Review of Biochemistry

Caveolin-1 Regulates the Antagonistic Pleiotropic Properties of Cellular Senescence through a Novel Mdm2/p53-Mediated Pathway

(2009) J. N. Bartholomew et al.   CANCER RESEARCH

Inhibition of thioredoxin reductase 1 by caveolin 1 promotes stress-induced premature senescence

(2009) Daniela Volonte et al.   EMBO REPORTS

Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats

(2009) Y-H Paik et al.   GUT

Molecular inflammation: Underpinnings of aging and age-related diseases

(2008) Hae Young Chung et al.   AGEING RESEARCH REVIEWS

Aging is associated with greater nuclear NFκB, reduced IκBα, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans

(2008) Anthony J. Donato et al.   AGING CELL

Non-redundant Functions of Cyclooxygenases: Oxygenation of Endocannabinoids

(2008) Carol A. Rouzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner

(2008) So Ra Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT