Dual κ-agonist/μ-antagonist opioid receptor modulation reduces levodopa-induced dyskinesia and corrects dysregulated striatal changes in the nonhuman primate model of Parkinson disease

Assessment of adverse effects of neurotropic drugs in monkeys with the “Drug Effects on the Nervous System” (DENS) scale

(2013) Subramaniam Uthayathas et al.   JOURNAL OF NEUROSCIENCE METHODS

Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l-DOPA-induced dyskinesia

(2013) Mathieu Bourdenx et al.   NEUROBIOLOGY OF DISEASE

l-DOPA-induced Dyskinesia is Associated with Regional Increase of Striatal Dynorphin Peptides as Elucidated by Imaging Mass Spectrometry

(2011) Jörg Hanrieder et al.   MOLECULAR & CELLULAR PROTEOMICS

The selective mu-opioid receptor antagonist adl5510 reduces levodopa-induced dyskinesia without affecting antiparkinsonian action in mptp-lesioned macaque model of Parkinson's disease

(2011) James B. Koprich et al.   MOVEMENT DISORDERS

Striatal inhibition of calpains prevents levodopa-induced neurochemical changes and abnormal involuntary movements in the hemiparkinsonian rat model

(2011) Laure Chagniel et al.   NEUROBIOLOGY OF DISEASE

Amantadine for Dyskinesias in Parkinson's Disease: A Randomized Controlled Trial

(2011) Hideyuki Sawada et al.   PLoS One

L-DOPA-Induced Dyskinesia and Abnormal Signaling in Striatal Medium Spiny Neurons: Focus on Dopamine D1 Receptor-Mediated Transmission

(2011) Michael Feyder et al.   Frontiers in Behavioral Neuroscience

Striatal Overexpression of  FosB Reproduces Chronic Levodopa-Induced Involuntary Movements

(2010) X. Cao et al.   JOURNAL OF NEUROSCIENCE

Distinct Changes in cAMP and Extracellular Signal-Regulated Protein Kinase Signalling in L-DOPA-Induced Dyskinesia

(2010) Emanuela Santini et al.   PLoS One

Distinct subclasses of medium spiny neurons differentially regulate striatal motor behaviors

(2010) H. S. Bateup et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRK-820, a selective kappa opioid receptor agonist, could effectively ameliorate L-DOPA-induced dyskinesia symptoms in a rat model of Parkinson's disease

(2009) Ken Ikeda et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Contribution of the striatum to the effects of 5-HT1A receptor stimulation in L-DOPA-treated hemiparkinsonian rats

(2009) Christopher Bishop et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Effect of non-dopaminergic drug treatment on Levodopa induced dyskinesias in MPTP monkeys: Common implication of striatal neuropeptides

(2009) Mohamed Khalil Tamim et al.   NEUROPHARMACOLOGY

Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

(2008) Helen S Bateup et al.   NATURE NEUROSCIENCE

Molecular mechanisms of L-DOPA-induced dyskinesia

(2008) Peter Jenner   NATURE REVIEWS NEUROSCIENCE