Developmental Plasticity, Epigenetics and Human Health

Association of Maternal Diabetes Mellitus in Pregnancy With Offspring Adiposity Into Early Adulthood

(2011) Debbie A. Lawlor et al.   CIRCULATION

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Exendin-4 increases histone acetylase activity and reverses epigenetic modifications that silence Pdx1 in the intrauterine growth retarded rat

(2011) S. E. Pinney et al.   DIABETOLOGIA

How evolutionary principles improve the understanding of human health and disease

(2011) Peter D. Gluckman et al.   Evolutionary Applications

The central role of RNA in human development and cognition

(2011) John S. Mattick   FEBS LETTERS

The Influence of Maternal Body Mass Index on Infant Adiposity and Hepatic Lipid Content

(2011) Neena Modi et al.   PEDIATRIC RESEARCH

Progressive, Transgenerational Changes in Offspring Phenotype and Epigenotype following Nutritional Transition

(2011) Graham C. Burdge et al.   PLoS One

Losing the War Against Obesity: The Need for a Developmental Perspective

(2011) P. D. Gluckman et al.   Science Translational Medicine

Weight gain in pregnancy and childhood body composition: findings from the Southampton Women’s Survey

(2010) Sarah R Crozier et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

The thrifty phenotype: An adaptation in growth or metabolism?

(2010) Jonathan C.K. Wells   AMERICAN JOURNAL OF HUMAN BIOLOGY

Epigenetic Transmission of the Impact of Early Stress Across Generations

(2010) Tamara B. Franklin et al.   BIOLOGICAL PSYCHIATRY

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses

(2010) Tim F. Oberlander et al.   Epigenetics

Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds

(2010) Rafael Guerrero-Preston et al.   Epigenetics

Chronic high-fat diet in fathers programs β-cell dysfunction in female rat offspring

(2010) Sheau-Fang Ng et al.   NATURE

Timing in Prenatal Nutrition: A Reprise of the Dutch Famine Study

(2010) Mervyn Susser et al.   NUTRITION REVIEWS

Epigenetic Transgenerational Actions of Vinclozolin on Promoter Regions of the Sperm Epigenome

(2010) Carlos Guerrero-Bosagna et al.   PLoS One

Developmental origins of metabolic disease: life course and intergenerational perspectives

(2010) Keith M. Godfrey et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Prenatal Exposure to apoE Deficiency and Postnatal Hypercholesterolemia Are Associated with Altered Cell-Specific Lysine Methyltransferase and Histone Methylation Patterns in the Vasculature

(2009) Fanneke E. Alkemade et al.   AMERICAN JOURNAL OF PATHOLOGY

The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction

(2009) Esther M. E. van Straten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice

(2009) Maqsood M. Elahi et al.   BRITISH JOURNAL OF NUTRITION

Contrasting patterns of transgenerational plasticity in ecologically distinct congeners

(2009) Sonia E. Sultan et al.   ECOLOGY

Maternal High-Fat Diet Promotes Body Length Increases and Insulin Insensitivity in Second-Generation Mice

(2009) Gregory A. Dunn et al.   ENDOCRINOLOGY

Influence of Prenatal Lead Exposure on Genomic Methylation of Cord Blood DNA

(2009) J. Richard Pilsner et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

The force of selection on the human life cycle

(2009) James Holland Jones   EVOLUTION AND HUMAN BEHAVIOR

Chromatin poises miRNA- and protein-coding genes for expression

(2009) A. Barski et al.   GENOME RESEARCH

Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression

(2009) Kimberley D. Bruce et al.   HEPATOLOGY

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

Epigenetic regulation of the glucocorticoid receptor in human brain associates with childhood abuse

(2009) Patrick O McGowan et al.   NATURE NEUROSCIENCE

Maternal Pregestational BMI Is Associated With Methylation of thePPARGC1APromoter in Newborns

(2009) Carolina Gemma et al.   Obesity

Relation of DNA Methylation of 5′-CpG Island of ACSL3 to Transplacental Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Childhood Asthma

(2009) Frederica Perera et al.   PLoS One

Pre- and Postnatal Nutritional Histories Influence Reproductive Maturation and Ovarian Function in the Rat

(2009) Deborah M. Sloboda et al.   PLoS One

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

(2009) Régine P. Steegers-Theunissen et al.   PLoS One

Brain Renin-Angiotensin System: Fetal Epigenetic Programming by Maternal Protein Restriction During Pregnancy

(2009) Ravi Goyal et al.   Reproductive Sciences

Transgenerational effects of prenatal exposure to the Dutch famine on neonatal adiposity and health in later life

(2008) RC Painter et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Statin Treatment in Hypercholesterolemic Pregnant Mice Reduces Cardiovascular Risk Factors in Their Offspring

(2008) Maqsood M. Elahi et al.   HYPERTENSION

Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

(2008) Kjersti M Aagaard-Tillery et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Promoter-Wide Hypermethylation of the Ribosomal RNA Gene Promoter in the Suicide Brain

(2008) Patrick O. McGowan et al.   PLoS One

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Predictive adaptive responses in perspective

(2008) Peter D. Gluckman et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM