Journal
ACS NANO
Volume 9, Issue 8, Pages 7867-7873Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.5b03567
Keywords
self-powered; low-level laser; embryonic osteoblast; proliferation; differentiation
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Funding
- Thousands Talents program for pioneer researcher, China [NSFC 31200702]
- Beijing Natural Science Foundation of China [4141002, 7132121]
- China Postdoctoral Science Foundation [2014M550031]
- Beijing Nova Program [Z121103002512019]
- Beijing Municipal Science & Technology Commission [Z131100006013004]
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Bone remodeling or orthodontic treatment is usually a long-term process. It is highly desirable to speed up the process for effective medical treatment. In this work, a self-powered low-level laser cure system for osteogenesis is developed using the power generated by the triboelectric nanogenerator. It is found that the system significantly accelerated the mouse embryonic osteoblasts' proliferation and differentiation, which is essential for bone and tooth healing. The system is further demonstrated to be driven by a living creature's motions, such as human walking or a mouse's breathing, suggesting its practical use as a portable or implantable clinical cure for bone remodeling or orthodontic treatment.
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