Behavioral and Neurochemical Effects of Alpha-Lipoic Acid in the Model of Parkinson’s Disease Induced by Unilateral Stereotaxic Injection of 6-Ohda in Rat

Lipoic acid – biological activity and therapeutic potential

(2014) Anna Gorąca et al.   Pharmacological Reports

Alpha-lipoic acid protects against 6-hydroxydopamine-induced neurotoxicity in a rat model of hemi-parkinsonism

(2013) Mohammadreza Jalali-Nadoushan et al.   BRAIN RESEARCH

Dual effects of l-DOPA on nigral dopaminergic neurons

(2013) Ezia Guatteo et al.   EXPERIMENTAL NEUROLOGY

Parkinson disease: from pathology to molecular disease mechanisms

(2013) David T. Dexter et al.   FREE RADICAL BIOLOGY AND MEDICINE

Targeting dysregulation of brain iron homeostasis in Parkinson's disease by iron chelators

(2013) Orly Weinreb et al.   FREE RADICAL BIOLOGY AND MEDICINE

Augmentation therapy with alpha-lipoic acid and desvenlafaxine: A future target for treatment of depression?

(2013) Márcia Calheiros Chaves Silva et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson’s disease

(2013) Juliet M. Taylor et al.   NEUROCHEMISTRY INTERNATIONAL

Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration

(2012) Ki Sung Kang et al.   BRAIN RESEARCH

Toxicity of 6-hydroxydopamine: live cell imaging of cytoplasmic redox flux

(2012) Colette T. Dooley et al.   CELL BIOLOGY AND TOXICOLOGY

Curcumin: A Potential Neuroprotective Agent in Parkinson's Disease

(2012) R. B. Mythri et al.   CURRENT PHARMACEUTICAL DESIGN

The oxidative damage and inflammation caused by pesticides are reverted by lipoic acid in rat brain

(2012) Mariana Astiz et al.   NEUROCHEMISTRY INTERNATIONAL

Closing the gap between clinic and cage: Sensori-motor and cognitive behavioural testing regimens in neurotoxin-induced animal models of Parkinson's disease

(2012) Ilse S. Pienaar et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Effects of natural antioxidants in neurodegenerative disease

(2012) Sonia Luz Albarracin et al.   NUTRITIONAL NEUROSCIENCE

Oxidative Stress and Epilepsy: Literature Review

(2012) Carlos Clayton Torres Aguiar et al.   Oxidative Medicine and Cellular Longevity

Novel Neurovascular Protective Agents: Effects of INV-155, INV-157, INV-159, and INV-161 versus Lipoic Acid and Captopril in a Rat Stroke Model

(2012) Barry J. Connell et al.   Cardiology Research and Practice

Excessive Expression of Hippocampal Ezrin Is Induced by Intrastriatal Injection of 6-Hydroxydopamine

(2011) Yosuke Matsumoto et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

The pyramidal neurons in the medial prefrontal cortex show decreased response to 5-hydroxytryptamine-3 receptor stimulation in a rodent model of Parkinson's disease

(2011) Qiao Jun Zhang et al.   BRAIN RESEARCH

Exploiting the lipoic acid structure in the search for novel multitarget ligands against Alzheimer’s disease

(2011) Michela Rosini et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Alpha-lipoic acid protects against myocardial ischemia/reperfusion injury via multiple target effects

(2011) Xin Wang et al.   FOOD AND CHEMICAL TOXICOLOGY

Bioorganic synthesis, characterization and antioxidant activity of esters of natural phenolics and α-lipoic acid

(2011) Shiva Shanker Kaki et al.   JOURNAL OF BIOTECHNOLOGY

Expression and functional properties of TRPM2 channels in dopaminergic neurons of the substantia nigra of the rat

(2011) Kenny K. H. Chung et al.   JOURNAL OF NEUROPHYSIOLOGY

Revisiting the relationship between essential tremor and Parkinson's disease

(2011) R. Fekete et al.   MOVEMENT DISORDERS

Neurotoxin-based models of Parkinson's disease

(2011) J. Bové et al.   NEUROSCIENCE

Intervention of mitochondrial dysfunction-oxidative stress-dependent apoptosis as a possible neuroprotective mechanism of α-lipoic acid against rotenone-induced parkinsonism and l-dopa toxicity

(2011) Amany A. Abdin et al.   NEUROSCIENCE RESEARCH

Acetyl-l-carnitine and α-lipoic acid affect rotenone-induced damage in nigral dopaminergic neurons of rat brain, implication for Parkinson's disease therapy

(2011) Sawsan A. Zaitone et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

l-DOPA: A scapegoat for accelerated neurodegeneration in Parkinson's disease?

(2011) Janusz Lipski et al.   PROGRESS IN NEUROBIOLOGY

Alterations on monoamines concentration in rat hippocampus produced by lipoic acid

(2010) Ítala Mônica de Sales Santos et al.   ARQUIVOS DE NEURO-PSIQUIATRIA

The Contributions Of Antioxidant Activity Of Lipoic Acid In Reducing Neurogenerative Progression Of Parkinson’s Disease: A Review

(2010) Dayane Pessoa De Araújo et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Deep Brain Stimulation of the Center Median-Parafascicular Complex of the Thalamus Has Efficient Anti-Parkinsonian Action Associated with Widespread Cellular Responses in the Basal Ganglia Network in a Rat Model of Parkinson's Disease

(2010) L. Jouve et al.   JOURNAL OF NEUROSCIENCE

Chemical physiology of oxidative stress-activated TRPM2 and TRPC5 channels

(2010) Shinichiro Yamamoto et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Treatment strategies for Parkinson’s disease

(2010) Hong Yuan et al.   Neuroscience Bulletin

Lipoic acid effects on lipid peroxidation level, superoxide dismutase activity and monoamines concentration in rat hippocampus

(2009) P.M.P. Ferreira et al.   NEUROSCIENCE LETTERS

α-Lipoic acid suppresses 6-hydroxydopamine-induced ROS generation and apoptosis through the stimulation of glutathione synthesis but not by the expression of heme oxygenase-1

(2008) Hirofumi Fujita et al.   BRAIN RESEARCH

The evaluation of effect of alpha-lipoic acid and vitamin E on the lipid peroxidation, gamma-amino butyric acid and serotonin level in the brain of mice (Mus musculus) acutely intoxicated with lindane

(2008) Renu Bist et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Oxidative and Inflammatory Pathways in Parkinson’s Disease

(2008) Rebecca L. Miller et al.   NEUROCHEMICAL RESEARCH