PI3K/Akt Pathway Contributes to Neurovascular Unit Protection ofXiao-Xu-MingDecoction against Focal Cerebral Ischemia and Reperfusion Injury in Rats

Leptin Attenuates Cerebral Ischemia Injury through the Promotion of Energy Metabolism via the PI3K/Akt Pathway

(2013) Jinying Zhang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats

(2012) Yong-Man Zhu et al.   BRAIN RESEARCH

Cerebralcare Granule® attenuates blood–brain barrier disruption after middle cerebral artery occlusion in rats

(2012) Ping Huang et al.   EXPERIMENTAL NEUROLOGY

The Flavonoid Fisetin Attenuates Postischemic Immune Cell Infiltration, Activation and Infarct Size after Transient Cerebral Middle Artery Occlusion in Mice

(2012) Mathias Gelderblom et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Glycyrrhizic acid affords robust neuroprotection in the postischemic brain via anti-inflammatory effect by inhibiting HMGB1 phosphorylation and secretion

(2012) Seung-Woo Kim et al.   NEUROBIOLOGY OF DISEASE

Apocynum venetum Leaf Extract Attenuates Disruption of the Blood–Brain Barrier and Upregulation of Matrix Metalloproteinase-9/-2 in a Rat Model of Cerebral Ischemia–Reperfusion Injury

(2012) Jun Xiang et al.   NEUROCHEMICAL RESEARCH

Targeting the neurovascular unit: Development of a new model and consideration for novel strategy for Alzheimer's disease

(2011) Rui Liu et al.   BRAIN RESEARCH BULLETIN

Traditional Chinese medicine, Xue-Fu-Zhu-Yu decoction, potentiates tissue plasminogen activator against thromboembolic stroke in rats

(2011) Jie-Jen Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Deciphering the neuroprotective mechanisms of Bu-yang Huan-wu decoction by an integrative neurofunctional and genomic approach in ischemic stroke mice

(2011) Hsei-Wei Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lutein enhances survival and reduces neuronal damage in a mouse model of ischemic stroke

(2011) Suk-Yee Li et al.   NEUROBIOLOGY OF DISEASE

Effect of Baicalin on Matrix Metalloproteinase-9 Expression and Blood–Brain Barrier Permeability Following Focal Cerebral Ischemia in Rats

(2011) Xian-kun Tu et al.   NEUROCHEMICAL RESEARCH

Delayed ischemic postconditioning protects hippocampal CA1 neurons by preserving mitochondrial integrity via Akt/GSK3β signaling

(2011) Caifeng Zhou et al.   NEUROCHEMISTRY INTERNATIONAL

The Anti-Inflammatory Effect of Paeoniflorin on Cerebral Infarction Induced by Ischemia-Reperfusion Injury in Sprague-Dawley Rats

(2010) Nou-Ying Tang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Baicalin attenuates focal cerebral ischemic reperfusion injury through inhibition of nuclear factor κB p65 activation

(2010) Xia Xue et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Acetaminophen reduces mitochondrial dysfunction during early cerebral postischemic reperfusion in rats

(2010) Sunanda S. Baliga et al.   BRAIN RESEARCH

Baicalin Inhibits TLR2/4 Signaling Pathway in Rat Brain Following Permanent Cerebral Ischemia

(2010) Xian-kun Tu et al.   INFLAMMATION

Chinese medicine Nao-Shuan-Tong attenuates cerebral ischemic injury by inhibiting apoptosis in a rat model of stroke

(2010) Jun Xiang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Targeting the neurovascular unit for treatment of neurological disorders

(2010) Reyna L. VanGilder et al.   PHARMACOLOGY & THERAPEUTICS

Baicalein is neuroprotective in rat MCAO model: Role of 12/15-lipoxygenase, mitogen-activated protein kinase and cytosolic phospholipase A2

(2010) Lili Cui et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

12/15-Lipoxygenase inhibitor baicalein suppresses PPARγ expression and nuclear translocation induced by cerebral ischemia/reperfusion

(2009) Yan-Wei Xu et al.   BRAIN RESEARCH

Simultaneous LC–MS Analysis and of Wogonin and Oroxylin A in Rat Plasma, and Pharmacokinetic Studies After Administration of the Active Fraction from Xiao-Xu-Ming Decoction

(2009) Kehe Du et al.   CHROMATOGRAPHIA

Neuroprotective Role of Lactate after Cerebral Ischemia

(2009) Carole Berthet et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Neuroprotective effects of Xiao-Xu-Ming decoction against ischemic neuronal injury in vivo and in vitro

(2009) Xin-Hong Zhu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Neuroprotection by baicalein in ischemic brain injury involves PTEN/AKT pathway

(2009) Chao Liu et al.   JOURNAL OF NEUROCHEMISTRY

Neuroprotective Effect of Baicalin in a Rat Model of Permanent Focal Cerebral Ischemia

(2009) Xian-kun Tu et al.   NEUROCHEMICAL RESEARCH

Identification of active compounds and their metabolites by high-performance liquid chromatography/electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry from Xiao-xu-ming decoction (XXMD)

(2009) Yilin Wang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Apoptotic Mechanisms After Cerebral Ischemia

(2009) Brad R.S. Broughton et al.   STROKE

Electrical Stimulation of the Cerebral Cortex Exerts Antiapoptotic, Angiogenic, and Anti-Inflammatory Effects in Ischemic Stroke Rats Through Phosphoinositide 3-Kinase/Akt Signaling Pathway

(2009) Tanefumi Baba et al.   STROKE

Ischemic Postconditioning Inhibits Apoptosis After Focal Cerebral Ischemia/Reperfusion Injury in the Rat

(2008) Bianzhi Xing et al.   STROKE