Review
Pharmacology & Pharmacy
Ziqi Chen, Yiwen Lv, Huachong Xu, Li Deng
Summary: COVID-19 is a respiratory disease caused by a virus, with symptoms ranging from mild to life-threatening. Some patients also experience gastrointestinal symptoms. Herbal medicine may play a role in recovering intestinal flora structure and modulating immune function for the treatment and recovery of COVID-19.
FRONTIERS IN PHARMACOLOGY
(2021)
Review
Veterinary Sciences
Ghulam Abbas, Jia Yu, Guangxing Li
Summary: The growth of poultry farming has resulted in increased transmission of infectious diseases among birds, causing significant harm to the poultry industry. Some pathogens may also cause zoonotic diseases. Traditional antiviral treatments have limitations, leading to a focus on herbal drugs and the use of nanotechnology for disease control in poultry.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Plant Sciences
Shiv Kumar Prajapati, Akanksha Malaiya, Gaurav Mishra, Dolly Jain, Payal Kesharwani, Nishi Mody, Amirhossein Ahmadi, Rishi Paliwal, Ankit Jain
Summary: The review emphasizes the potential of herbal medicines in enhancing immunity and treating COVID-19, highlighting their importance in combating SARS-COV-2 infection and potential future applications.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Review
Pharmacology & Pharmacy
Yi-Chang Su, Guan-Jhong Huang, Jaung-Geng Lin
Summary: This article reviews the use of traditional Chinese medicine (TCM) in the treatment of COVID-19 and analyzes its potential antiviral, anti-inflammatory, and immunomodulatory activities. The study finds that many TCM components can target multiple pathways and have the potential to prevent and treat COVID-19. Therefore, TCM may be an effective treatment option.
FRONTIERS IN PHARMACOLOGY
(2022)
Review
Chemistry, Medicinal
Mohamad H. Shahrajabian, Wenli Sun, Ali Soleymani, Qi Cheng
Summary: Mental health is crucial to personal wellbeing and productivity. Traditional herbal medicines have been used for centuries to treat anxiety and depression. SARS, MERS, and COVID-19 are all associated with different types of coronaviruses.
PHYTOTHERAPY RESEARCH
(2021)
Editorial Material
Biochemistry & Molecular Biology
Rebekah Honce, Stacey Schultz-Cherry
Summary: Avian influenza viruses can infect mammals, and the mutations accumulated in viruses obtained from humans infected with emerging avian H3N8 viruses can promote respiratory droplet transmission and disease in mammals.
Review
Plant Sciences
Zhonglei Wang, Liyan Yang
Summary: Traditional Chinese herbal medicines have shown promising potential for treating COVID-19, including active ingredients, monomer preparations, crude extracts, and formulas, all of which have potential activity against SARS-CoV-2 and have shown significant effects both in vitro and in clinical practice. As a key component of the COVID-19 treatment regimen, Chinese herbal medicines have played an irreplaceable role in the treatment of SARS-CoV-2 infection.
JOURNAL OF ETHNOPHARMACOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Guohui Wei, Xianjun Fu, Xueying He, Peng Qiu, Lu Yue, Rong Rong, Zhenguo Wang
Summary: This study analyzed the chemical components of 61 Chinese herbal medicines using GC technology and constructed a predictive identification model through distance metric learning algorithm and improved k-nearest neighbor algorithm, confirming the relationship between the "cold-hot nature" of Chinese herbal medicines and the similarity of their chemical components, with better predictive performance than existing classical models.
Review
Plant Sciences
Kanika Khanna, Sukhmeen Kaur Kohli, Ravdeep Kaur, Abhay Bhardwaj, Vinay Bhardwaj, Puja Ohri, Anket Sharma, Ajaz Ahmad, Renu Bhardwaj, Parvaiz Ahmad
Summary: The world is currently facing the COVID-19 pandemic, which requires urgent public health measures to control the spread of the virus. Social distancing and quarantines have become essential to fight the global threat, as the lack of drugs and vaccines against COVID-19 continues to be a challenge. Scientific communities are actively researching to develop effective therapeutics against SARS-CoV-2, while also exploring traditional medicines as a potential solution.
Article
Pharmacology & Pharmacy
Fan Yang, Qi Zhang, Zhongshang Yuan, Saisai Teng, Lizhen Cui, Fuzhong Xue, Leyi Wei
Summary: COVID-19 has spread globally, and supportive treatment is still the main therapy. Herbal medicine plays a key role in identifying and treating symptoms, with the National Health Commission of China recommending six effective herbal formulas for treating COVID-19.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Immunology
Shannon H. Baumer-Mouradian, Rebecca J. Hart, Alexis Visotcky, Raphael Fraser, Swathi Prasad, Michael Levas, Mark Nimmer, David C. Brousseau
Summary: This study compared vaccine hesitancy levels for influenza and SARS-CoV-2 among Black, Hispanic, and White parents/caregivers and identified barriers and facilitators to vaccine acceptance.
Article
Pharmacology & Pharmacy
Eun-Bin Kwon, You-Chang Oh, Youn-Hwan Hwang, Wei Li, Seok-Man Park, Ryong Kong, Young Soo Kim, Jang-Gi Choi
Summary: OCD20015-V009 modulates murine innate immune response by regulating macrophages to inhibit influenza A virus replication, reducing mortality in infected mice. Chlorogenic acid and ginsenoside Rd are identified as antiviral components in this herbal mix, enhancing mice's resistance to viral infections. Further studies are needed to clarify the protective effects of active components in OCD20015-V009 against influenza A viruses.
FRONTIERS IN PHARMACOLOGY
(2021)
Editorial Material
Biology
Arturo Barbachano-Guerrero, Daniel R. Perez, Sara L. Sawyer
Summary: The H3N2 canine influenza virus, originating from birds, is undergoing evolution to increase its transmissibility among dogs.
Article
Biochemistry & Molecular Biology
Hezha O. Rasul, Noel Vinay Thomas, Dlzar D. Ghafour, Bakhtyar K. Aziz, M. Guillermo Salgado, L. H. Mendoza-Huizar, Lorena Gerli Candia
Summary: The new coronavirus disease (COVID-19) is the biggest threat to civilization since World War II, and there is an urgent need for innovative therapeutic medicines to treat it. Reusing bio-actives is an efficient strategy in the battle against new epidemics due to the time-consuming process of developing new drugs. This research aimed to identify herbal remedies with high affinity for the receptor and assess their potential as targets to suppress the SARS-CoV-2 M-pro.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Review
Virology
Umarqayum AbuBakar, Lina Amrani, Farah Ayuni Kamarulzaman, Saiful Anuar Karsani, Pouya Hassandarvish, Jasmine Elanie Khairat
Summary: An influenza pandemic occurs when a new influenza A virus is able to infect and transmit efficiently to a new host species. The emergence of pandemics is influenced by both viral and host factors. The interaction between the virus and the host determines the virus tropism, including binding, replication, assembly, and transmission between individuals. Avian influenza virus (AIV), which mainly infects wild birds asymptomatically, can cross into new species and occasionally achieve human-to-human transmission. This review focuses on the determinants of AIV for initiating a human pandemic and discusses the mechanisms of AIV mutation for establishing tropism and stable human adaptation. Understanding AIV tropism is crucial for preventing human transmission and improving vaccine and therapeutic agent design.