Editorial Material
Biochemistry & Molecular Biology
Roger Li
Summary: The response to neoadjuvant treatment can stratify individuals with muscle-invasive bladder cancer according to their risk of progression, allowing bladder-sparing treatments for some patients and indicating a shift from the current one-size-fits-all approach.
Article
Oncology
Martin Swinton, Neethu Billy Graham Mariam, Jean Ling Tan, Katherine Murphy, Thiraviyam Elumalai, Manjusha Soni, Alexandra Ferrera, Charlotte Richardson, Richard Walshaw, Hitesh Mistry, Vijay Ramani, Yeepei Song, Alison Birtle, Ann Henry, Joachim Chan, Peter Hoskin, Ananya Choudhury
Summary: This study analyzed the survival outcomes of node-positive bladder cancer patients and found that there was no significant difference in survival rates between surgery and radiation therapy. Bladder-sparing treatment should be considered as an option for patients with poor survival rates.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Article
Oncology
Stefano Tappero, Andrea Panunzio, Lukas Hohenhorst, Cristina Cano Garcia, Francesco Barletta, Mattia Piccinelli, Zhe Tian, Stefano Parodi, Alessandro Antonelli, Markus Graefen, Felix K. H. Chun, Alberto Briganti, Ottavio De Cobelli, Fred Saad, Shahrokh F. Shariat, Nazareno Suardi, Marco Borghesi, Carlo Terrone, Pierre I. Karakiewicz
Summary: The effect of radical cystectomy (RC) on cancer-specific mortality (CSM) is uncertain in non-metastatic sarcomatoid bladder cancer (SBC) patients. This study aimed to evaluate the benefit of RC in SBC patients and compare it with urothelial bladder cancer (UCB).
Article
Urology & Nephrology
Francesco Soria, Peter C. Black, Adrian S. Fairey, Michael S. Cookson, Evan Y. Yu, Wassim Kassouf, Marc A. Dall'Era, Srikala S. Sridhar, John S. McGrath, Jonathan L. Wright, Andrew C. Thorpe, Todd M. Morgan, Siamak Daneshmand, Jeff M. Holzbeierlein, Trinity J. Bivalacqua, Scott North, Daniel A. Barocas, Yair Lotan, Petros Grivas, Andrew J. Stephenson, Jay B. Shah, Bas W. van Rhijn, Philippe E. Spiess, Shahrokh F. Shariat, Paolo Gontero
Summary: In patients with cT2N0 bladder cancer and no preoperative hydronephrosis, neoadjuvant chemotherapy (NAC) increased the rate of pathological complete response and downstaging, showing a positive impact on overall survival.
Review
Urology & Nephrology
Ekaterina Laukhtina, Markus von Deimling, Benjamin Pradere, Takafumi Yanagisawa, Pawel Rajwa, Tatsushi Kawada, Fahad Quhal, Maximilian Pallauf, Alberto Bianchi, Muhammad Majdoub, Hadi Mostafaei, Reza Sari Motlagh, Keiichiro Mori, Dmitry Enikeev, Margit Fisch, Marco Moschini, David D'Andrea, Francesco Soria, Simone Albisinni, Harun Fajkovic, Michael Rink, Jeremy Yuen-Chun Teoh, Paolo F. Gontero, Shahrokh F. Shariat
Summary: This study aimed to determine and summarize the functional outcomes, including urinary, sexual, and health-related quality of life (HRQOL), after traditional radical cystectomy (RC), reproductive organ-preserving RC (ROPRC), and nerve-sparing RC (NSRC) for bladder cancer (BCa) in female patients. The study found that organ- and nerve-sparing surgical approaches resulted in improved voiding function. However, due to the use of different assessment tools for sexual and HRQOL outcomes, a systematic comparison was not possible.
Article
Urology & Nephrology
Alberto Martini, Luca Afferi, Stefania Zamboni, Julianne G. Schultz, Chiara Lonati, Agostino Mattei, R. Jeffrey Karnes, Matteo Soligo, Armando Stabile, Ettore Di Trapani, Ottavio De Cobelli, Giuseppe Simone, Claudio Simeone, Mario Alvarez-Maestro, Giorgio Gandaglia, Andrea Gallina, Renzo Colombo, Alberto Briganti, Francesco Montorsi, Evanguelos Xylinas, Shahrokh F. Shariat, Marco Moschini
Summary: The study found that patients with variant histology bladder cancer have a higher risk of recurrence, requiring extended surveillance time, and different histological types have different risks of recurrence and metastasis.
JOURNAL OF UROLOGY
(2021)
Review
Oncology
Xiaozhe Su, Caitao Dong, Wenbiao Liao, Wentao Liu
Summary: The study found that radical cystectomy (RC) has better treatment outcomes in terms of overall survival and cancer-specific survival compared to trimodal therapy (TMT). Unless patients cannot tolerate or have a strong desire to preserve the bladder, RC should be chosen over TMT in treatment.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
Aleksander Slusarczyk, Piotr Zapala, Tomasz Piecha, Lukasz Zapala, Tomasz Borkowski, Piotr Radziszewski
Summary: The study found that patients who underwent radical nephroureterectomy for upper urinary tract urothelial cancer after radical cystectomy experienced poor overall survival and cancer-specific survival, with most surgeries being performed for locally advanced tumors. Independent risk factors for worse survival included UTUC T stage, presence of metastasis, and male gender.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Urology & Nephrology
Carl J. Wijburg, Charlotte T. J. Michels, Gerjon Hannink, Janneke P. C. Grutters, Maroeska M. Rovers, J. Alfred Witjes
Summary: This study did not find significant differences in complications and health-related quality of life between robot-assisted radical cystectomy and open radical cystectomy. However, there were some differences in secondary outcomes, with the main limitation being residual confounding.
Article
Biochemistry & Molecular Biology
Matthew D. Galsky, Siamak Daneshmand, Sudeh Izadmehr, Edgar Gonzalez-Kozlova, Kevin G. Chan, Sara Lewis, Bassam El Achkar, Tanya B. Dorff, Jeremy Paul Cetnar, Brock O. Neil, Anishka D'Souza, Ronac Mamtani, Christos Kyriakopoulos, Tomi Jun, Mahalya Gogerly-Moragoda, Rachel Brody, Hui Xie, Kai Nie, Geoffrey Kelly, Amir Horwitz, Yayoi Kinoshita, Ethan Ellis, Yohei Nose, Giorgio Ioannou, Rafael Cabal, G. Kenneth Haines, Li Wang, Kent W. Mouw, Robert M. Samstein, Reza Mehrazin, Nina Bhardwaj, Menggang Yu, Qianqian Zhao, Seunghee Kim-Schulze, Robert Sebra, Jun Zhu, Sacha Gnjatic, John Sfakianos, Sumanta K. Pal
Summary: Cystectomy is a commonly used treatment for muscle-invasive bladder cancer, but it has significant impact on patients' lives. This study aimed to evaluate the clinical complete response rate and the predictive value of clinical complete response for survival in patients with muscle-invasive bladder cancer.
Review
Medicine, General & Internal
Vincent D. D'Andrea, Kevin Melnick, Kendrick Yim, John Ernandez, Nnamdi Onochie, Timothy N. Clinton, Graeme S. Steele, Mark A. Preston, Adam S. Kibel, Matthew Mossanen
Summary: The study analyzed and reviewed the critical steps of open radical cystectomy and developed a concise guide. Through evidence-based assessment, valuable information for optimizing surgical techniques and patient outcomes is provided.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Wenlong Zhong, Kun Xia, Libo Liu, Sida Cheng, Peng Hong, Wang He, Wen Dong, Hao Liu, Yiming Lai, Han Hao, Cheng Liu, Hongxian Zhang, Xinfei Li, Guangpu Ding, Xuesong Li, Lulin Ma, Liqun Zhou, Tianxin Lin, Jian Huang
Summary: This study compared the long-term oncological outcomes of pelvic organ preserving-radical cystectomy (POPRC) and standard radical cystectomy (SRC) in female patients with bladder cancer. The results showed no significant difference in overall survival between the two surgical methods.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Oncology
John P. Stein, Gary Lieskovsky, Richard Cote, Susan Groshen, An-Chen Feng, Stuart Boyd, Eila Skinner, Bernard Bocher, Duriayai Thangathurai, Maged Mikhail, Derek Raghavan, Donald G. Skinner
Summary: This study evaluated the long-term clinical outcomes of patients with invasive bladder cancer who underwent radical cystectomy and pelvic lymph node dissection. The results showed that the primary bladder tumor stage and lymph node status were associated with the prognosis of patients.
JOURNAL OF CLINICAL ONCOLOGY
(2023)
Review
Oncology
Khatereh Aminoltejari, Amanda E. Hird, Zachary Klaassen, Raj Satkunasivam, Girish S. Kulkarni, Amy N. Luckenbaugh, Aaron A. Laviana, Christopher J. D. Wallis, Roderick Clark
Summary: This study compared robotic assisted radical cystectomy (RARC) with open radical cystectomy (ORC) through systematic reviews. The findings show that RARC has advantages in terms of less blood loss, lower transfusion rates, and longer operative time compared to ORC. However, there is limited evidence on differences in hospital length of stay, complication rates, oncologic outcomes, and QOL between the two approaches. Further prospective studies are needed to evaluate the impact of diversion type, technique, and recovery pathways on patient outcomes.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Oncology
M. . Carmen Mir, Riccardo Campi, Yohann Loriot, Javier Puente, Gianluca Giannarini, Andrea Necchi, Morgan Roupret
Summary: This case study discusses the treatment of a 71-year-old woman with locally advanced bladder cancer and chronic kidney disease. The patient underwent neoadjuvant immunotherapy and radical cystectomy, and the role of adjuvant chemotherapy and immunotherapy in high-risk bladder cancer patients is explored.
EUROPEAN UROLOGY ONCOLOGY
(2022)
Letter
Oncology
David A. Siegel, Stacey A. Fedewa, S. Jane Henley, Lori A. Pollack, Ahmedin Jemal
Summary: This study investigates the smoking patterns of lung cancer patients based on demographic and clinical characteristics.
Letter
Public, Environmental & Occupational Health
Zhiyuan Zheng, Stacey A. Fedewa, Xuesong Han, K. Robin Yabroff
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2021)
Letter
Critical Care Medicine
Stacey A. Fedewa, Priti Bandi, Robert A. Smith, Gerard A. Silvestri, Ahmedin Jemal
Letter
Medicine, General & Internal
Samuel Asare, Anuja Majmundar, Farhad Islami, Priti Bandi, Stacey Fedewa, Lee J. Westmaas, Nigar Nargis
ANNALS OF INTERNAL MEDICINE
(2022)
Article
Oncology
Farhad Islami, Carmen E. Guerra, Adair Minihan, K. Robin Yabroff, Stacey A. Fedewa, Kirsten Sloan, Tracy L. Wiedt, Blake Thomson, Rebecca L. Siegel, Nigar Nargis, Robert A. Winn, Lisa Lacasse, Laura Makaroff, Elvan C. Daniels, Alpa Patel, William G. Cance, Ahmedin Jemal
Summary: This report provides comprehensive data on disparities in cancer occurrence, risk factors, and access to preventive measures and screening in the US. Policy recommendations are made to reduce these inequalities, emphasizing the need for broad implementation of evidence-based interventions to address social inequities and systemic racism.
CA-A CANCER JOURNAL FOR CLINICIANS
(2022)
Article
Oncology
Stacey A. Fedewa, K. Robin Yabroff, Priti Bandi, Robert A. Smith, Nigar Nargis, Zhiyuan Zheng, Jeffrey Drope, Ahmedin Jemal
Summary: The study found a negative association between unemployment and cancer screening, which was mainly due to a lack of health insurance coverage.
Article
Oncology
Liora Sahar, Vanhvilai L. Douangchai Wills, Ka Kit (Antonio) Liu, Stacey A. Fedewa, Lauren Rosenthal, Ella A. Kazerooni, Debra S. Dyer, Robert A. Smith
Summary: This study examines access to lung cancer screening nationwide and across rural and urban settings. Geographic information system network analysis is used to estimate access at different distances, and the results show disparities in accessibility between regions and across rural and urban environments. Approximately 5% of the eligible population does not have access to screening facilities within 40 miles, and rural areas have a larger proportion of the population with no access.
Editorial Material
Gastroenterology & Hepatology
Stacey A. Fedewa
Article
Public, Environmental & Occupational Health
Priti Bandi, Samuel Asare, Anuja Majmundar, Nigar Nargis, Ahmedin Jemal, Stacey A. Fedewa
Summary: Perceptions of E-cigarettes as more harmful than cigarettes increased significantly between 2019 and 2020. Increases in tobacco product use may be guided by individuals' product-specific relative harm perceptions, highlighting the need for accurate messaging about relative and absolute product risks.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2022)
Article
Oncology
Jingxuan Zhao, Xuesong Han, Leticia Nogueira, Stacey A. Fedewa, Ahmedin Jemal, Michael T. Halpern, K. Robin Yabroff
Summary: Previous studies have shown that uninsured patients in the United States are more likely to be diagnosed with late-stage cancer and have worse survival rates. This report provides comprehensive data on the association between health insurance coverage type and stage at diagnosis and long-term survival in individuals diagnosed with common cancers between 2010 and 2013.
CA-A CANCER JOURNAL FOR CLINICIANS
(2022)
Article
Health Care Sciences & Services
Natalia Ramirez, Kewei Shi, K. Robin Yabroff, Xuesong Han, Stacey A. Fedewa, Leticia M. Nogueira
Summary: This study investigates the association between limited English proficiency (LEP) and access to healthcare in adults. The results show that adults with LEP have worse access to care and are more likely to be overdue for preventive services compared to those without LEP. System-level interventions can improve equity in access to care for adults with LEP.
JOURNAL OF GENERAL INTERNAL MEDICINE
(2023)
Article
Public, Environmental & Occupational Health
Jessica Star, Priti Bandi, Adair K. Minihan, Ahmedin Jemal, Stacey A. Fedewa
Summary: This study examines the first year of breast cancer screening data among 1375 Community Health Centers (CHCs) in the United States. The findings show that less than half of eligible women received screening, and disparities exist for clinics with high proportions of Black and uninsured patients. CHCs in Medicaid expansion states and in the Northeast have higher screening rates.
PREVENTIVE MEDICINE
(2022)
Article
Medicine, General & Internal
Stacey A. Fedewa, Jessica Star, Priti Bandi, Adair Minihan, Xuesong Han, K. Robin Yabroff, Ahmedin Jemal
Summary: Health care services, including cancer screenings, were disrupted in the US during the COVID-19 pandemic. This survey study found that breast cancer and cervical cancer screenings slightly decreased in 2020, while colorectal cancer screenings remained steady. Stool testing increased, offsetting the decrease in colonoscopy.
Article
Oncology
Xuesong Han, Sylvia Kewei Shi, Jingxuan Zhao, Leticia M. Nogueira, Priti Bandi, Stacey A. Fedewa, Ahmedin Jemal, K. Robin Yabroff
Summary: This study investigated the health changes among cancer survivors during the COVID-19 pandemic. The study found that among adults aged 18-64 years, the uninsured rate did not change significantly, but the prevalence of unhealthy behaviors decreased and self-rated health improved. Few changes were observed for adults aged 65 years and above. Further research is needed to confirm these findings and investigate the long-term effects of the pandemic on cancer survivors.
Article
Oncology
Katherine S. Virgo, R. Bryan Rumble, James Talcott
JOURNAL OF CLINICAL ONCOLOGY
(2023)