Article
Oncology
Irene Barjolle, Loic Ah-Thiane, Eric Frampas, Georges Karam, Jerome Rigaud, Arthur David
Summary: This retrospective descriptive study evaluated the efficacy and safety of cryoablation for T1b renal tumors. The results showed good oncologic outcomes and low rates of complications, supporting cryoablation as a potential alternative to surgery for tumors up to 7 cm in diameter.
FRONTIERS IN ONCOLOGY
(2023)
Article
Oncology
YuChen Bai, YunKai Yang, HaiBin Wei, Jing Quan, Fei Wei, Qi Zhang, Feng Liu
Summary: This study investigated the safety and efficacy of renal hypothermic perfusion during robot-assisted laparoscopic partial nephrectomy for patients with complex renal tumors. The results showed that renal hypothermic perfusion is a safe and feasible surgical approach.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Liangyou Gu, Wenlei Zhao, Junnan Xu, Baojun Wang, Qiang Cheng, Donglai Shen, Yundong Xuan, Xupeng Zhao, Hongzhao Li, Xin Ma, Xu Zhang
Summary: This study compared the outcomes of transperitoneal robotic partial nephrectomy (TRPN) and retroperitoneal robotic partial nephrectomy (RRPN) for complete upper pole renal masses. The results showed no significant differences between the two surgical approaches in terms of operating time, renal artery clamping time, and postoperative complications. However, TRPN was associated with greater estimated blood loss. Multivariate analysis identified that RENAL score was independently associated with the achievement of treatment success.
FRONTIERS IN ONCOLOGY
(2022)
Review
Urology & Nephrology
Antonio Celia, Claudio Pusceddu, Tommaso Silvestri, Giovanni B. Gidaro, Fabrizio Iannello, Elena P. Lanati, Anna D'Ausilio
Summary: The study found that in Italy, PCA is not only more cost-effective than OPN in treating small renal masses, but also more resource-efficient from both the National Healthcare System and hospital perspectives.
MINERVA UROLOGY AND NEPHROLOGY
(2021)
Article
Medicine, General & Internal
Wenlei Zhao, Yancai Ding, Dong Chen, Yundong Xuan, Zhiqiang Chen, Xupeng Zhao, Bin Jiang, Baojun Wang, Hongzhao Li, Chengliang Yin, Xin Ma, Gang Guo, Liangyou Gu, Xu Zhang
Summary: This study compared the perioperative outcomes of robotic partial nephrectomy via transperitoneal and retroperitoneal approaches for completely lower pole renal tumors. The results showed no significant differences between the two approaches in terms of blood loss, operative time, ischemia time, postoperative complications, and tumor size. Therefore, both approaches are feasible options for completely lower pole renal tumors.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Urology & Nephrology
Fabrizio Gallo, Simone Sforza, Lorenzo Luciani, Daniele Mattevi, Paolo Barzaghi, Andrea Mari, Fabrizio Di Maida, Alessandro Antonelli, Luca Cindolo, Antonio Galfano, Giovannalberto Pini, Guglielmo Mantica, Maurizio Schenone, Luigi Schips, Filippo Annino, Carlo Terrone, Aldo Massimo Bocciardi, Franco Gaboardi, Andrea Minervini
Summary: Our data indicate that simultaneous bilateral RAPNs could be a safe and feasible procedure with promising results for the treatment of bilateral synchronous renal masses in selected patients and expert hands.
WORLD JOURNAL OF UROLOGY
(2022)
Article
Oncology
Shohei Kawaguchi, Kouji Izumi, Renato Naito, Suguru Kadomoto, Hiroaki Iwamoto, Hiroshi Yaegashi, Takahiro Nohara, Kazuyoshi Shigehara, Kotaro Yoshida, Yoshifumi Kadono, Atsushi Mizokami
Summary: Advances in diagnostic imaging have led to increased opportunities for treating small-diameter renal cell carcinomas in the elderly. This study compared the efficacy of RAPN and PCA in elderly patients with small-diameter renal cell carcinomas, finding that RAPN is a safe and effective treatment, while PCA is a safe alternative for high-risk patients.
Article
Oncology
Haichang Li, Yuning Hu, Dongning Lu, Jingyun Wang, Yanze Lin, Xugang Zhong, Yixuan Mou, Cenchao Yao, Zhida Wang, Xinyu Zhang, Qijun Wo, Hanbo Liu, Feng Liu, Dahong Zhang, Heng Wang
Summary: Based on a retrospective analysis, this study compared the feasibility and safety of zero ischaemia robotic-assisted laparoscopic partial nephrectomy (RALPN) after preoperative superselective transarterial embolization (STE) to standard RALPN and off-clamp RALPN. The results showed that zero ischaemia RALPN can preserve more renal function and provide a safe and feasible surgical method for patients with renal tumors.
FRONTIERS IN ONCOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Xiao Wu, Johannes Uhlig, Brian M. Shuch, Annemarie Uhlig, Hyun S. Kim
Summary: In this study, a cost-effectiveness analysis was performed to assess the benefits of partial nephrectomy (PN) and percutaneous cryoablation (PCA) for patients with cT1a renal cell carcinoma (RCC). The results suggest that PCA is more cost-effective than PN in the majority of scenarios, although the currently available evidence is of limited quality.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Hui-Ying Liu, Chih-Hsiung Kang, Hung-Jen Wang, Chien-Hsu Chen, Hao-Lun Luo, Yen-Ta Chen, Yuan-Tso Cheng, Po-Hui Chiang
Summary: The study found that robot-assisted laparoscopic partial nephrectomy and laparoscopic cryoablation had similar outcomes in treating localized T1-T2 renal tumors, with cryoablation having shorter operative time and less blood loss, and without compromising oncological outcomes.
Article
Radiology, Nuclear Medicine & Medical Imaging
Vanessa Acosta Ruiz, Sarah Batelsson, Elina Onkamo, Lisa Wernroth, Thomas Nilsson, Maria Loennemark, Paer Dahlman, Anders Magnusson
Summary: This study compared renal function after RFA and LPN treatment of small renal masses, finding that LPN resulted in greater reduction of split renal function in the affected kidney compared to RFA. However, there was no difference between the two groups in terms of changes in creatinine and eGFR levels.
Review
Oncology
Li Wang, Jing-ya Deng, Cai Liang, Ping-yu Zhu
Summary: This study compared the outcomes of robotic partial nephrectomy (RPN) and laparoscopic partial nephrectomy (LPN) for treating complex renal tumors. The results showed that RPN was associated with shorter operative time, warm ischemia time, length of stay, lower transfusion rate, and incidence of intraoperative complications compared to LPN, while maintaining oncological control and avoiding renal function decline.
FRONTIERS IN ONCOLOGY
(2023)
Article
Medicine, General & Internal
Gerard Bray, Arya Bahadori, Derek Mao, Sachinka Ranasinghe, Christopher Tracey
Summary: This study compares peri-operative and post-operative outcomes between robotic assisted and laparoscopic partial nephrectomy. The results show that robotic assisted partial nephrectomy has shorter warm ischemia time, shorter length of stay, and less acute renal function deterioration compared to laparoscopic partial nephrectomy.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Urology & Nephrology
Yifan Sun, Wei Wang, Qing Zhang, Xiaozhi Zhao, Linfeng Xu, Hongqian Guo
Summary: The use of intraoperative ultrasound (IOUS) in robotic-assisted renal partial nephrectomy (RAPN) for endophytic renal tumors significantly reduces estimated blood loss, shortens warm ischemia time, and improves Margin, Ischemia, and Complications (MIC) rate and Pentafecta achievement. RAPN with IOUS is an independent predictor of MIC achievement and provides favorable perioperative outcomes and surgical margin rates.
INTERNATIONAL UROLOGY AND NEPHROLOGY
(2021)
Article
Urology & Nephrology
Fabrizio Gallo, Simone Sforza, Andrea Mari, Lorenzo Luciani, Maurizio Schenone, Andrea Minervini
Summary: The study shows that bilateral RAPN is effective and safe for treating bilateral renal masses. However, these results may only apply to selected patients who undergo complex surgeries by expert robotic surgeons at high volume centers, and cannot be generalized to all patients or centers.
CURRENT UROLOGY REPORTS
(2023)
Article
Oncology
Francesco Del Giudice, Jianlin Huang, Shufeng Li, Simon Sorensen, Ekene Enemchukwu, Martina Maggi, Stefano Salciccia, Matteo Ferro, Felice Crocetto, Savio Domenico Pandolfo, Riccardo Autorino, Wojciech Krajewski, Simone Crivellaro, Giovanni E. Cacciamani, Eugenio Bologna, Vincenzo Asero, Carlo Scornajenghi, Marco Moschini, David D'Andrea, David R. Brown, Benjamin Chung
Summary: This study aimed to identify trends, costs, and predictors in the use of different surgical procedures for post-radical prostatectomy incontinence (PPI). The results showed that male slings were the most common procedure, while the use of an artificial urinary sphincter (AUS) was the most expensive option. Patient's comorbidity history, radiation therapy, and neurological comorbidities were found to be predictors of incontinence surgery.
PROSTATE CANCER AND PROSTATIC DISEASES
(2023)
Article
Oncology
Cristian Fiori, Enrico Checcucci, Ilaria Stura, Daniele Amparore, Sabrina De Cillis, Alberto Piana, Stefano Granato, Gabriele Volpi, Michele Sica, Federico Piramide, Paolo Verri, Matteo Manfredi, Stefano De Luca, Riccardo Autorino, Giuseppe Migliaretti, Francesco Porpiglia
Summary: This study aimed to develop a model based on mp-MRI and target biopsy (TB) alone to predict the risk of lymph-node invasion (LNI). Using logistic regression analysis, a model was created and a nomogram was generated to predict the risk of LNI. The model showed good discrimination and was able to identify patients with LNI risk above 7%.
PROSTATE CANCER AND PROSTATIC DISEASES
(2023)
Review
Pharmacology & Pharmacy
Nathaniel M. Rickles, Mary Mulrooney, Diana Sobieraj, Adrian V. Hernandez, Laura L. Manzey, Julie A. Gouveia-Pisano, Kevin A. Townsend, Heidi Luder, Joseph C. Cappelleri, Carl J. Possidente
Summary: This systematic review aimed to identify validated, self-reported medication adherence tools applicable to primary care and summarize selected features as an assessment of clinical feasibility and applicability. The study found considerable variability in the characteristics of self-reported adherence tools, and clinicians should consider their measurement validity and practicality when selecting a tool. There is a critical need for adherence tool developers to establish a key list of tool characteristics to facilitate practical comparisons among tools.
JOURNAL OF THE AMERICAN PHARMACISTS ASSOCIATION
(2023)
Review
Oncology
Savio Domenico Pandolfo, Francesco Del Giudice, Benjamin Chung, Celeste Manfredi, Marco De Sio, Rocco Damiano, Edward E. Cherullo, Cosimo De Nunzio, Giovanni E. Cacciamani, Luca Cindolo, Francesco Porpiglia, Vincenzo Mirone, Ciro Imbimbo, Riccardo Autorino, Fabio Crocerossa
Summary: This study provides a comprehensive analysis comparing the safety and effectiveness of robot-assisted simple prostatectomy (RASP) to open simple prostatectomy (OSP), laparoscopic simple prostatectomy (LSP), and laser enucleation of the prostate (EEP). The results reveal that RASP has better safety and functional outcomes in the treatment of bladder prostatic obstruction caused by large prostate glands.
PROSTATE CANCER AND PROSTATIC DISEASES
(2023)
Article
Cardiac & Cardiovascular Systems
Josias C. Rios-Ortega, Luisa Talledo-Paredes, Cristian Yepez-Calder, Edmy Callalli-Mattos, Silvana Gonzales-Castro, Ali Al-kassab-Cordova, Cristian Aguilar-Carranza, Yemmy Perez-Valverde, Adrian V. Hernandez, Edward Mezones-Holguin
Summary: This study aimed to evaluate the safety and outcomes of a new surgical technique for adult patients with a giant left atrium. The study analyzed patients who underwent left atrium reduction surgery between 2016 and 2020. The results showed that the surgical technique improved clinical functionality and reduced the size of the giant left atrium in patients.
Review
Oncology
Dakota Sicignano, Kimberly Snow-Caroti, Adrian V. Hernandez, C. Michael White
Summary: This study systematically reviewed and conducted meta-analyses on the use of validated anxiety and depression scales in patients with cancer or other life-threatening diseases. The findings suggest that psychedelics may have potential in reducing anxiety and depressive symptoms, but there are concerns regarding increased blood pressure and heart rate. Further research is needed to determine the optimal psychedelic, dosage, number of sessions required, and the response of psychedelic-naive patients before considering widespread clinical use of this therapy.
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
(2023)
Review
Medicine, General & Internal
Francesco Lasorsa, Monica Rutigliano, Martina Milella, Matteo Ferro, Savio Domenico Pandolfo, Felice Crocetto, Octavian Sabin Tataru, Riccardo Autorino, Michele Battaglia, Pasquale Ditonno, Giuseppe Lucarelli
Summary: Globally, clear-cell renal cell carcinoma (ccRCC) is the most prevalent type of kidney cancer. Surgery is key in treatment, but a significant number of patients have metastatic ccRCC or experience recurrence. Molecular-target-based agents like TKIs and ICIs are recommended for advanced cancer treatment. The tumor microenvironment (TME) plays an essential role in cancer development and can be targeted for therapy. Understanding immune cell interactions with cancer and other TME elements is crucial for enhancing immunotherapies and reducing resistance.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Oncology
Francesco Del Giudice, Vincenzo Asero, Eugenio Bologna, Carlo Maria Scornajenghi, Dalila Carino, Virginia Dolci, Pietro Viscuso, Stefano Salciccia, Alessandro Sciarra, David D'Andrea, Benjamin Pradere, Marco Moschini, Andrea Mari, Simone Albisinni, Wojciech Krajewski, Tomasz Szydelko, Bartosz Malkiewicz, Lukasz Nowak, Ekaterina Laukhtina, Andrea Gallioli, Laura S. Mertens, Gautier Marcq, Alessia Cimadamore, Luca Afferi, Francesco Soria, Keiichiro Mori, Karl Heinrich Tully, Renate Pichler, Matteo Ferro, Octavian Sabin Tataru, Riccardo Autorino, Simone Crivellaro, Felice Crocetto, Gian Maria Busetto, Satvir Basran, Michael L. Eisenberg, Benjamin Inbeh Chung, Ettore De Berardinis
Summary: In this systematic review and meta-analysis, the cumulative bladder cancer (BC) recurrence rates and efficacy profile of different Bacillus of Calmette-Guerin (BCG) strains were compared. The study found that BCG Tokyo 172 had the lowest recurrence rate among studies with <= 3-year recurrence-free survival (RFS). No significant difference was observed among strains in >3-year RFS outcomes. The genetically different BCG strains RIVM, Tice, and Tokyo 172 showed some potential enhanced benefits.
Article
Urology & Nephrology
Roberto Contieri, Rodolfo Hurle, Marco Paciotti, Paolo Casale, Alberto Saita, Francesco Porpiglia, Cristian Fiori, Biagio Barone, Felice Crocetto, Giuseppe Lucarelli, Gian M. Busetto, Francesco Del Giudice, Martina Maggi, Francesco Cantiello, Rocco Damiano, Marco Borghesi, Pierluigi Bove, Riccardo Bertolo, Rocco Papalia, Andrea Mari, Stefano Luzzago, Francesco A. Mistretta, Francesco Soria, Paolo Gontero, Michele Marchioni, Evelina La Civita, Daniela Terracciano, Giorgio I. Russo, Luigi Schips, Sisto Perdona, Vincenzo Mirone, Octavian S. Tataru, Gennaro Musi, Mihai D. Vartolomei, Riccardo Autorino, Emanuele Montanari, Ottavio De Cobelli, Matteo Ferro
Summary: The European Association of Urology has updated the prognostic factor risk groups model for NMIBC and introduced a new group of patients at very high risk (VHR). They also proposed three additional clinical risk factors. However, the new scoring model was created without considering patients who received BCG intravesical therapy.
MINERVA UROLOGY AND NEPHROLOGY
(2023)
Review
Pharmacology & Pharmacy
Dakota J. Sicignano, Ryan Kurschner, Nissen Weisman, Ava Sedensky, Adrian V. Hernandez, C. Michael White
Summary: Ketamine has a modest effect in reducing PTSD and depression symptoms as early as the first day of therapy, but more research is needed to determine its long-term effectiveness. It is not superior to SSRIs and venlafaxine in chronic use.
ANNALS OF PHARMACOTHERAPY
(2023)
Meeting Abstract
Urology & Nephrology
Rocco Simone Flammia, Umberto Anceschi, Aldo Brassetti, Mariaconsiglia Ferriero, Riccardo Mastroianni, Leonardo Misuraca, Gabriele Tuderti, Antonio Tufano, Costantino Leonardo, Michele Gallucci, Porpiglia Francesco, Daniele Amparore, Andrea Minervini, Andrea Mari, Andre Antonio Grasso, Riccardo Autorino, Daniel Eun, Alessandro Larcher, Umberto Capitanio, Giuseppe Simone, Eugenio Bologna
JOURNAL OF UROLOGY
(2023)
Meeting Abstract
Urology & Nephrology
Nathan Schuler, Lauren Shepard, Craig Rogers, Riccardo Autorino, Sammy Elsamara, Simone Crivellaro, Jean Joseph, Ahmed Ghazi
JOURNAL OF UROLOGY
(2023)
Meeting Abstract
Urology & Nephrology
Jason Zappia, Courtney Yong, Zhenije Wu, Linhui Wang, Hooman Djaladat, Erika Wood, Alireza Ghoreifi, Firas Abdollah, Matthew Davis, Alex Stephens, Giuseppe Simone, Gabriele Tuderti, Mark Gonzalgo, Dinno Mendiola, Ithaar Derweesh, Sohail Dhanji, Kevin Hakimi, Vitaly Margulis, Jacob Taylor, Matteo Ferro, Marco Tozzi, Riccardo Autorino, Savio Pandolfo, Reza Mehrazin, Benjamine Eilender, Francesco Porpiglia, Enrico Checcucci, Daniel Eun, Spencer Bell, Chandru Sundaram
JOURNAL OF UROLOGY
(2023)
Meeting Abstract
Urology & Nephrology
Rocco Simone Flammia, Umberto Anceschi, Aldo Brassetti, Mariaconsiglia Ferriero, Riccardo Mastroianni, Leonardo Misuraca, Gabriele Tuderti, Antonio Tufano, Salvatore Guaglianone, Costantino Leonardo, Michele Gallucci, Porpiglia Francesco, Daniele Amparore, Andrea Minervini, Andrea Mari, Andre Antonio Grasso, Ithaar Derweesh, Riccardo Autorino, Daniel Eun, Alessandro Larcher, Umberto Capitanio, Carlo Andrea Bravi, Alexander Mottrie, Giuseppe Simone
JOURNAL OF UROLOGY
(2023)
Article
Urology & Nephrology
Clara Cerrato, Devin Patel, Riccardo Autorino, Giuseppe Simone, Bo Yang, Robert Uzzo, Francesco Porpiglia, Umberto Capitanio, James Porter, Alp Tuna Beksac, Andrea Minervini, Alessandro Antonelli, Maria Angela Cerruto, Clayton Lau, Akbar Ashrafi, Daniel Eun, Alexandre Mottrie, Carmen Mir, Margaret F. Meagher, Dhruv Puri, Mimi Nguyen, Sohail Dhanji, Franklin Liu, Savio D. Pandolfo, Alexander Kutikov, Francesco Montorsi, Inderbir S. Gill, Chandru Sundaram, Jihad Kaouk, Ithaar H. Derweesh
Summary: This study compares the outcomes of robotic-assisted partial nephrectomy (RAPN) and minimally invasive radical nephrectomy (MIS-RN) for complex renal masses (CRM). The results indicate that RAPN is not associated with increased risk of complications or worsened oncological outcomes compared to MIS-RN, and may be preferred when clinically indicated.
WORLD JOURNAL OF UROLOGY
(2023)