Article
Urology & Nephrology
Shubo Fan, Zhongyuan Zhang, Jie Wang, Shengwei Xiong, Xiaofei Dai, Xu Chen, Zhihua Li, Guanpeng Han, Jun Zhu, Han Hao, Wei Yu, Liang Cui, Cheng Shen, Xuesong Li, Liqun Zhou
Summary: This study evaluated the feasibility, safety, and effectiveness of the KD-SR-01 system for robot-assisted radical prostatectomy. The results showed that the system was successfully used in all cases without complications. The surgical outcomes were satisfactory, with low blood loss and good postoperative recovery.
JOURNAL OF UROLOGY
(2022)
Article
Medicine, General & Internal
Mahmoud Farzat, Mohamed Elsherif, Florian M. M. Wagenlehner
Summary: This study investigates the impact of operating time on outcomes after robot-assisted radical prostatectomy (RARP). It found that longer operating time is associated with increased hospital stay, catheter days, and major complications. Prostate volume is the only predictor of prolonged operating time.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Urology & Nephrology
Antonio Galfano, Stefano Tappero, Christopher Eden, Paolo Dell'oglio, Karen Fransis, Hongqian Guo, Keith Kowalczyk, Mattia Longoni, Rabii Madi, Koon H. Rha, Silvia Secco, Xuefeng Qiu, Rashid Sayyid, Aldo M. Bocciardi
Summary: This study retrospectively evaluated the results of Retzius-Sparing robot-assisted radical Prostatectomy (RSP) in high-risk prostate cancer (HR-PCa) patients, performed by expert surgeons in a multicentric setting. The study found that RSP achieved good urinary continence recovery and could predict the occurrence of positive surgical margins (PSMs) to some extent.
MINERVA UROLOGY AND NEPHROLOGY
(2022)
Article
Urology & Nephrology
Sami-Ramzi Leyh-Bannurah, Christian Wagner, Andreas Schuette, Mustapha Addali, Nikolaos Liakos, Katarina Urbanova, Mikolaj Mendrek, Matthias Oelke, Jorn H. Witt
Summary: The study found limited accuracy of different AS sets for stricter iPCa definitions, which declined with advanced age. More stringent AS sets resulted in more AS ineligible patients, despite having iPCa.
MINERVA UROLOGY AND NEPHROLOGY
(2022)
Article
Oncology
Chao-Yu Hsu, Che-Hsueh Yang, Min-Che Tung, Hung-Jen Liu, Yen-Chuan Ou
Summary: This study found that theranostic robot-assisted radical prostatectomy (T-RARP) can detect about 75% of prostate cancer cases and provide better functional recovery outcomes for clinically highly suspicious prostate cancer patients. However, in some cases with benign pathology, there may be complications such as urinary incontinence and erectile dysfunction.
Article
Medicine, General & Internal
Eoin Dinneen, Clare Allen, Tom Strange, Daniel Heffernan-Ho, Jelena Banjeglav, Jamie Lindsay, John-Patrick Mulligan, Tim Briggs, Senthil Nathan, Ashwin Sridhar, Jack Grierson, Aiman Haider, Christos Panayi, Dominic Patel, Alex Freeman, Jonathan Aning, Raj Persad, Imran Ahmad, Lorenzo Dutto, Neil Oakley, Alessandro Ambrosi, Tom Parry, Veeru Kasivisvanathan, Francesco Giganti, Greg Shaw, Shonit Punwani
Summary: This study evaluated the ability of mpMRI to accurately predict extra-prostatic extension (EPE) of prostate cancer and found that multiparametric scanning and higher image quality can improve the reliability of the predictions. This provides valuable information for surgical planning in men undergoing robot-assisted prostatectomy.
Review
Urology & Nephrology
Umberto Carbonara, Maya Srinath, Fabio Crocerossa, Matteo Ferro, Francesco Cantiello, Giuseppe Lucarelli, Francesco Porpiglia, Michele Battaglia, Pasquale Ditonno, Riccardo Autorino
Summary: A systematic analysis found that robot-assisted radical prostatectomy (RARP) offers better outcomes compared to laparoscopic radical prostatectomy (LRP) in treating prostate cancer, with higher rates of erectile function recovery, lower urinary incontinence rate, and decreased likelihood of biochemical recurrence.
WORLD JOURNAL OF UROLOGY
(2021)
Article
Multidisciplinary Sciences
Jaehun Jung, Gi Hwan Bae, Jae Heon Kim, Jaehong Kim
Summary: This study aimed to evaluate the clinical impact of robot-assisted radical prostatectomy (RARP) on health outcomes in Korean patients with prostate cancer (PCa). The study found that RARP had a higher risk of overall mortality within 3 and 12 months compared to radical prostatectomy (RP). The RARP group in hospitals with the largest PCa surgery volume had higher mortality rates and more surgical complications than the total RARP patients. The study suggests that RARP may not be superior to RP, possibly due to increased robotic surgery in the elderly.
SCIENTIFIC REPORTS
(2023)
Article
Andrology
Christopher Gossler, Johannes Hillinger, Maximilian Burger, Johannes Brundl, Stefan Denzinger, Michael Gierth, Johannes Breyer
Summary: Lymphoceles are common postoperative complications after radical prostatectomy with pelvic lymphadenectomy, affecting around 6.9% of patients who undergo robot-assisted radical prostatectomy. The study shows that laparoscopic fenestration is the most effective treatment option for symptomatic lymphoceles, while cannulation and drainage, as well as drainage and instillation, have not been proven effective.
TRANSLATIONAL ANDROLOGY AND UROLOGY
(2021)
Article
Urology & Nephrology
Shubo Fan, Han Hao, Silu Chen, Jie Wang, Xiaofei Dai, Meng Zhang, Xu Chen, Zhihua Li, Shengwei Xiong, Guanpeng Han, Jun Zhu, Zhongyuan Zhang, Wei Yu, Liang Cui, Cheng Shen, Liqun Zhou, Xuesong Li
Summary: This study compared the efficacy and safety of robot-assisted laparoscopic radical prostatectomy (RARP) performed using the KangDuo surgical robot system to the da Vinci Si robotic system in clinically localized prostate cancer (KD-RARP vs DV-RARP). The results showed that there were no significant differences between the two groups in basic clinical characteristics, but KD-RARP had a significantly longer operation time. There were also no significant differences between the two groups in terms of postoperative outcomes. Overall, the KangDuo surgical robot system achieved similar short-term oncological and functional outcomes compared to the da Vinci Si robotic system, but with a disadvantage in operation time.
JOURNAL OF ENDOUROLOGY
(2023)
Article
Oncology
Muhieddine Labban, Nicola Frego, Zhiyu Jason Qian, Mara Koelker, Stephen Reese, Agim Aliaj, Alexander P. Cole, Steven L. Chang, Mark A. Preston, Adam S. Kibel, Quoc-Dien Trinh
Summary: This study reports on the trends, predictors, and patient outcomes of same-day discharge (SDD) versus non-SDD for robot-assisted laparoscopic radical prostatectomy (RALP). The results show that in our health system, the use of SDD is safe and currently comprises half of our RALP volume.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2023)
Article
Urology & Nephrology
Turki Altaylouni, Pimrapat Gebert, Sefer Elezkurtaj, Florian Rossner, Bernhard Ralla, Sarah Weinberger, Diana Moldovan, Thorsten Schlomm, Bertrand Guillonneau
Summary: We investigated the improvement in pathological outcomes with experience and surgeon generation after robot-assisted laparoscopic prostatectomy (RALP). A study was conducted on 1338 patients who underwent RALP between February 2010 and April 2020. Learning curves were created for pelvic lymph node dissection (PLND), number of lymph nodes (LNs) removed, and positive surgical margin (PSM) after adjusting for confounders. The study found that experience and surgeon generation had a significant impact on PLND and LN removal, but not on PSM.
JOURNAL OF ENDOUROLOGY
(2023)
Article
Surgery
Kulthe Ramesh Seetharam Bhat, Marcio Covas Moschovas, Fikret Fatih Onol, Travis Rogers, Sunil Sandadi Reddy, Cathy Corder, Shannon Roof, Vipul R. Patel
Summary: Robot-assisted laparoscopic radical prostatectomy (RALP) has become the standard surgical care in the USA and worldwide. With 13,000 procedures performed over the past 18 years, the surgical technique has evolved, leading to optimal patient outcomes.
JOURNAL OF ROBOTIC SURGERY
(2021)
Article
Urology & Nephrology
Francesco Porpiglia, Enrico Checcucci, Daniele Amparore, Gabriel Niculescu, Gabriele Volpi, Federico Piramide, Sabrina De Cillis, Matteo Manfredi, Riccardo Autorino, Cristian Fiori
Summary: In patients with large BPH, our technique of urethral-sparing robotic-assisted simple prostatectomy (usRASP) has been shown to be a safe and effective procedure, allowing resolution of lower urinary tract symptoms and maintenance of ejaculatory function in a high percentage of patients.
Article
Urology & Nephrology
Kyohei Hakozaki, Toshikazu Takeda, Yota Yasumizu, Nobuyuki Tanaka, Kazuhiro Matsumoto, Shinya Morita, Takeo Kosaka, Ryuichi Mizuno, Hiroshi Asanuma, Mototsugu Oya
Summary: The aim of this study was to identify predictors of urinary continence recovery among patients with urinary incontinence immediately after surgery. The study found that age and intraoperative blood loss were predictors affecting urinary continence recovery one year after surgery. Younger patients and those with higher intraoperative blood loss can recover urinary continence one year after surgery.
INTERNATIONAL BRAZ J UROL
(2023)
Article
Oncology
E. Lopci, G. Lughezzani, A. Castello, P. Colombo, P. Casale, A. Saita, N. M. Buffi, G. Guazzoni, A. Chiti, M. Lazzeri
Summary: In a highly-selected patient population, Ga-68-PSMA PET/CT demonstrates a higher diagnostic performance compared to PRI-MUS in the primary diagnosis of prostate cancer.
CLINICAL & TRANSLATIONAL ONCOLOGY
(2021)
Article
Urology & Nephrology
Bianca Oresta, Daniele Braga, Massimo Lazzeri, Nicola Frego, Alberto Saita, Cristina Faccani, Vittorio Fasulo, Piergiuseppe Colombo, Giorgio Guazzoni, Rodolfo Hurle, Maria Rescigno
Summary: Our study found that the urinary microbiome of male bladder cancer patients collected from catheterized urine samples is characterized by an increased abundance of Veillonella and Corynebacterium, and decreased Ruminococcus compared to controls. Different taxonomic profiles were observed in bladder washouts and midstream urines, with specific taxa showing enrichment in each sample type. These findings suggest potential diagnostic and therapeutic implications based on manipulation of the urinary microbiome.
JOURNAL OF UROLOGY
(2021)
Article
Oncology
Rodolfo Hurle, Roberto Contieri, Paolo Casale, Emanuela Morenghi, Alberto Saita, Nicolomaria Buffi, Giovanni Lughezzani, Piergiuseppe Colombo, Nicola Frego, Vittorio Fasulo, Marco Paciotti, Giorgio Guazzoni, Massimo Lazzeri
Summary: The study reported mid-term results of intravesical gemcitabine in non-muscle-invasive bladder cancer patients, showing a disease-free survival rate of 32.69% at 3 years. The most common adverse events were urinary symptoms and fatigue.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2021)
Article
Urology & Nephrology
Giovanni Lughezzani, Davide Maffei, Alberto Saita, Marco Paciotti, Pietro Diana, Nicolo Maria Buffi, Piergiuseppe Colombo, Grazia Maria Elefante, Rodolfo Hurle, Massimo Lazzeri, Giorgio Guazzoni, Paolo Casale
Summary: This study aimed to evaluate the accuracy of microultrasound in diagnosing clinically significant prostate cancer, finding that microultrasound has high sensitivity but low specificity in the diagnosis of csPCa.
EUROPEAN UROLOGY FOCUS
(2021)
Article
Education, Scientific Disciplines
Adam M. Gordon, Thomas E. Ahlering
Summary: The study compared the expenses of United States medical students applying to the 5 most competitive surgical residencies by geographic region. It found that in different geographic regions, neurosurgery and plastic surgery applicants spent more on interviews, away rotations, and total costs relative to students in other specialties.
JOURNAL OF SURGICAL EDUCATION
(2022)
Article
Urology & Nephrology
Linda My Huynh, Erica Huang, Maxwell Towe, Karren Liang, Farouk M. el Khatib, Faysal A. Yafi, Thomas E. Ahlering
Summary: The study found that total testosterone remained stable in men aged 40-80 years, while free testosterone decreased by 2-3% each year. Low free testosterone independently predicted high-risk prostate cancer and biochemical recurrence.
Article
Oncology
Rodolfo Hurle, Giorgio Guazzoni, Piergiuseppe Colombo, Armando Santoro, Ottavio De Cobelli, Ettore Di Trapani, Gloria Nohales, Llorente Carlos, Ramon Duran-Merino, Massimo Lazzeri
Summary: This study evaluates the safety and efficacy of Oncofid-P-B in CIS patients who are unresponsive or intolerant to BCG, showing a 75% complete response rate after 12 weeks of treatment and a 40% complete response rate still after 15 months. Only 7 drug-related adverse events were reported, with drug concentrations below the limit of quantification in all plasma samples.
UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
(2022)
Article
Urology & Nephrology
Vittorio Fasulo, Nicolo Maria Buffi, Federica Regis, Marco Paciotti, Fancesco Persico, Davide Maffei, Alessandro Uleri, Alberto Saita, Paolo Casale, Rodolfo Hurle, Massimo Lazzeri, Giorgio Guazzoni, Giovanni Lughezzani
Summary: This study evaluated the accuracy of micro-ultrasound in predicting extraprostatic extension of Prostate Cancer prior to surgery. The results showed that micro-ultrasound can accurately predict extraprostatic extension at the final pathology report in patients scheduled for robot-assisted radical prostatectomy.
WORLD JOURNAL OF UROLOGY
(2022)
Article
Oncology
Vittorio Fasulo, Marco Paciotti, Massimo Lazzeri, Roberto Contieri, Paolo Casale, Alberto Saita, Giovanni Lughezzani, Pietro Diana, Nicola Frego, Pier Paolo Avolio, Piergiuseppe Colombo, Grazia Maria Elefante, Giorgio Guazzoni, Nicolo Maria Buffi, Michael Bates, Rodolfo Hurle
Summary: The study found that longitudinally repeating the Xpert BC Monitor assay can significantly reduce the number of unnecessary cystoscopies and urine cytology during follow-up.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Pietro Diana, Giovanni Lughezzani, Alberto Saita, Alessandro Uleri, Nicola Frego, Roberto Contieri, Nicolomaria Buffi, Luca Balzarini, Federico D'Orazio, Colombo Piergiuseppe, Maria Grazia Elefante, Massimo Lazzeri, Giorgio Guazzoni, Paolo Casale, Rodolfo Hurle
Summary: This study compared the diagnostic accuracy of 29-MHz high-resolution micro-ultrasound (mUS) and magnetic resonance imaging (MRI) in differentiating non-muscle invasive bladder cancer (NMIBC) and muscle-invasive bladder cancer (MIBC). The results showed that mUS had a better performance in distinguishing NMIBC from MIBC. However, the main limitation of mUS was its probe shape, which made its use problematic in cases with a large prostate and inadequate rectal preparation.
Article
Surgery
Nicola Frego, Marco Paciotti, Nicolo Maria Buffi, Davide Maffei, Roberto Contieri, Pier Paolo Avolio, Vittorio Fasulo, Alessandro Uleri, Massimo Lazzeri, Rodolfo Hurle, Alberto Saita, Giorgio Ferruccio Guazzoni, Paolo Casale, Giovanni Lughezzani
Summary: In this study, the performance of the Briganti 2012 and Briganti 2019 nomograms in predicting lymph node invasion (LNI) was externally validated and compared. The results showed that the updated Briganti 2019 nomogram, which included MRI and MRI-targeted biopsy data, was not significantly more accurate than the 2012 model in predicting LNI. This suggests a negligible role of mpMRI in the current population.
FRONTIERS IN SURGERY
(2022)
Article
Oncology
Erica Huang, Linda My Huynh, Joshua Tran, Adam M. Gordon, Ryan Chandhoke, Blanca Morales, Douglas Skarecky, Thomas E. Ahlering
Summary: This observational study on 407 patients with biochemical recurrence (BCR) following radical prostatectomy (RP) shows that one-third of men can be managed with active observation without the risk of prostate-related death. These findings support the idea that a significant portion of men following RP develop a benign recurrence that does not require treatment intervention.
Article
Oncology
Erica Huang, Joshua Tran, Linda My Huynh, Douglas Skarecky, Robert H. Wilson, Thomas Ahlering
Summary: PSA doubling time kinetics can accurately predict the need for treatment in patients with biochemical recurrence following radical prostatectomy. One-third of the biochemical recurrences were determined to be low-risk and safely followed without treatment. This approach can prevent overtreatment and improve patient quality of life.
Article
Oncology
Roberto Contieri, Marco Paciotti, Giovanni Lughezzani, Nicolo M. Buffi, Nicola Frego, Pietro Diana, Vittorio Fasulo, Alberto Saita, Paolo Casale, Massimo Lazzeri, Giorgio Guazzoni, Rodolfo Hurle
Summary: This study reports the long-term results and factors associated with failure in patients undergoing active surveillance for recurrent low-risk non-muscle-invasive bladder cancer. The findings suggest that well-selected patients with low-grade tumors can safely undergo active surveillance for an extended period, while multiple transurethral resections and multiple lesions at enrollment are associated with a higher risk of failure.
EUROPEAN UROLOGY ONCOLOGY
(2022)
Article
Urology & Nephrology
Massimo Lazzeri, Stefano Duga, Elena Azzolini, Vittorio Fasulo, Nicolo Buffi, Alberto Saita, Giovanni Lughezzani, Elvezia M. Paraboschi, Rodolfo Hurle, Alessandro Nobili, Maurizio Cecconi, Giorgio Guazzoni, Paolo Casale, Rosanna Asselta
Summary: This study compared the hospitalization rates for COVID-19 between males exposed to 5ARIs and a control group, and found that males exposed to 5ARIs had a lower risk of hospitalization. This suggests the potential protective effect of 5ARIs against severe COVID-19.
MINERVA UROLOGY AND NEPHROLOGY
(2022)