Damage- and Pathogen-Associated Molecular Patterns and Alarmins: Keys to Sepsis?

Activation of toll-like receptor, RAGE and HMGB1 signalling in malformations of cortical development

(2011) E. Zurolo et al.   BRAIN

Sensing disease and danger: A survey of vertebrate PRRs and their origins

(2011) John D. Hansen et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

RIG-I-like receptors: cytoplasmic sensors for non-self RNA

(2011) Hiroki Kato et al.   IMMUNOLOGICAL REVIEWS

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

(2011) Dmitri V. Krysko et al.   TRENDS IN IMMUNOLOGY

Characterization and Modulation of the Immunosuppressive Phase of Sepsis

(2010) J. T. Muenzer et al.   INFECTION AND IMMUNITY

Molecular Intercommunication between the Complement and Coagulation Systems

(2010) U. Amara et al.   JOURNAL OF IMMUNOLOGY

Pivotal Advance: The pattern recognition receptor ligands lipopolysaccharide and polyinosine-polycytidylic acid stimulate factor B synthesis by the macrophage through distinct but overlapping mechanisms

(2010) David J. Kaczorowski et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Circulating mitochondrial DAMPs cause inflammatory responses to injury

(2010) Qin Zhang et al.   NATURE

Crosstalk pathways between Toll-like receptors and the complement system

(2010) George Hajishengallis et al.   TRENDS IN IMMUNOLOGY

Mitochondrial Peptides Are Potent Immune Activators That Activate Human Neutrophils Via FPR-1

(2010) Mustafa Raoof et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Nucleophosmin may act as an alarmin: implications for severe sepsis

(2009) Yuko Nawa et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The role of the anaphylatoxins in health and disease

(2009) Andreas Klos et al.   MOLECULAR IMMUNOLOGY

Extracellular histones are major mediators of death in sepsis

(2009) Jun Xu et al.   NATURE MEDICINE

Sepsis: the dark side of histones

(2009) Catherine Chaput et al.   NATURE MEDICINE

The danger within: endogenous danger signals, atopy and asthma

(2008) M. A. M. Willart et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Cell-Free Plasma DNA as a Predictor of Outcome in Severe Sepsis and Septic Shock

(2008) K. Saukkonen et al.   CLINICAL CHEMISTRY

Functions of the complement components C3 and C5 during sepsis

(2008) Michael A. Flierl et al.   FASEB JOURNAL

Functional roles for C5a receptors in sepsis

(2008) Daniel Rittirsch et al.   NATURE MEDICINE