Article
Cardiac & Cardiovascular Systems
Maxim Avanesov, Julius Matthias Weinrich, Martin Sinn, Alexander Lenz, Felicia von Duering, Johannes Salamon, Frank-Oliver Henes, Bjoern Peter Schoennagel, Gerhard Adam, Yskert von Kodolitsch, Peter Bannas
Summary: This study compared aortic measurements at 1.5T and 3T using non-contrast MRA in Marfan patients. The results showed higher interobserver agreement in pre-surgical patients at 3T, while worse image quality and artifacts were observed in post-surgical patients at 3T. Different magnetic field strengths are recommended for monitoring aortic growth in pre- and post-surgical Marfan patients.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Alexander Lenz, Malte Warncke, Felicia Wright, Julius Matthias Weinrich, Bjoern P. Schoennagel, Frank Oliver Henes, Gerhard Adam, Yskert von Kodolitsch, Gerhard Schoen, Peter Bannas
Summary: This study aimed to compare the growth rates of the distal aorta in Marfan patients with and without aortic root replacement. The study found that Marfan patients who underwent aortic root replacement had a higher growth rate in the distal thoracic aorta compared to those without replacement.
EUROPEAN RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Felicia Wright, Malte Warncke, Martin Sinn, Inka Ristow, Alexander Lenz, Christoph Riedel, Bjoern P. Schoennagel, Shuo Zhang, Michael G. Kaul, Gerhard Adam, Yskert von Kodolitsch, Susanne Sehner, Peter Bannas
Summary: This study compared the accuracy and precision of 3D-Dixon and 2D-SSFP MR imaging for assessing aortic diameter in Marfan patients. The results showed that both respiratory-gated 3D-Dixon and breath-hold 2D-SSFP MR imaging provided accurate and precise measurements of aortic diameter. However, 3D-Dixon imaging had fewer imaging artifacts and the advantage of orthogonal multiplanar reformations of the aortic root, making it recommended for monitoring aortic diameter in Marfan patients.
EUROPEAN RADIOLOGY
(2023)
Article
Nanoscience & Nanotechnology
Shengxiang Fu, Zhongyuan Cai, Li Liu, Xiaomin Fu, Changqiang Wu, Liang Du, Chunchao Xia, Su Lui, Qiyong Gong, Bin Song, Hua Ai
Summary: Compared to traditional branched polymers, branched polymers with Gd(III) chelates as the internal skeleton show higher kinetic stability and better relaxivity enhancement for MRI contrast agents. Different poly-DOTA branched polymers were synthesized and the Gd(III) chelates displayed excellent stability and high T1 relaxivities. In vivo studies showed that P4-Gd had the best performance in terms of MRA effect, vascular stenosis detection, and longer observation window compared to Gd-DOTA. Overall, poly-DOTA branched polymers with Gd(III) chelates are promising candidates for MRI probes with improved relaxivity enhancement.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Cardiac & Cardiovascular Systems
Carsten Gietzen, Lenhard Pennig, Jennifer von Stein, Henning Guthoff, Kilian Weiss, Roman Gertz, Iris Thuerbach, Alexander C. Bunck, David Maintz, Stephan Baldus, Henrik Ten Freyhaus, Christopher Hohmann, Philipp von Stein
Summary: This study compared the measurement of aortic diameters using a novel flow-independent MR-Angiography method and trans-thoracic echocardiography in patients with Marfan syndrome. The results showed strong correlation between the two methods, but the diameters measured by echocardiography were larger.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Logan R. Smith, Stephen N. Darty, Elizabeth R. Jenista, George L. Gamoneda, David C. Wendell, Clerio F. Azevedo, Michele A. Parker, Raymond J. Kim, Han W. Kim
Summary: This study directly compared the impact of ECG gating on diameter measurements in the same patient for 3D contrast-enhanced MR angiography (CE-MRA), finding that ECG gating resulted in improved image quality and measurement reproducibility, particularly for the evaluation of the ascending aorta.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Toshimasa J. Clark, Gregory J. Wilson, Jeffrey H. Maki
Summary: This study utilized computer modeling to evaluate the impact of contrast signal intensity evolution under different injection strategies on CE-MRA imaging. The results indicate that shorter plateau lengths and lower tail heights lead to increased measurement errors and blurring in the imaging. Optimal contrast injection guidelines were proposed for minimal degradation in CE-MRA imaging.
JOURNAL OF MAGNETIC RESONANCE IMAGING
(2022)
Article
Cardiac & Cardiovascular Systems
Minghui Hua, Yufan Gao, Jianhui Li, Fang Tong, Ximing Li, Hong Zhang
Summary: This report presents a rare case of intramural pseudoaneurysm in the left ventricle, which was successfully repaired surgically with a good prognosis. The rupture of the left sinus Valsalva aneurysm may be associated with acute ozone inhalation and long-term hypertension.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Clinical Neurology
Sung-Hye You, Byungjun Kim, Kyung-Sook Yang, Bo Kyu Kim, Jaeil Ryu
Summary: This study evaluated the diagnostic performance of PETRA-MRA compared to TOF-MRA and CE-MRA in patients who underwent endovascular coiling. PETRA showed superior sensitivity in detecting residual flow and in-stent flow assessment.
Article
Medicine, General & Internal
Jung Sun Cho, Joonhong Park, Jong Bum Kwon, Dae-Won Kim, Mahn-Won Park
Summary: This case report demonstrates the use of a personalized 3D printed external aortic root model for surgical treatment of a Marfan syndrome patient, with successful matching of the actual surgical shape. This approach may help reduce postoperative complications and improve surgical outcomes.
Review
Cardiac & Cardiovascular Systems
Aryan Ayati, Neda Toofaninejad, Ali Hosseinsabet, Fatemeh Mohammadi, Kaveh Hosseini
Summary: This study is a systematic review on the transcatheter closure (TCC) of ruptured sinus of Valsalva (RSOV). The success rate of TCC was 95.6%, but there were still complications such as residual shunts, significant worsening of aortic insufficiency, and RSOV recurrence. Therefore, careful patient selection is necessary.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Neuroimaging
Sishi Xiang, Fu Fan, Peng Hu, Kun Yang, Xiaodong Zhai, Jiewen Geng, Zhe Ji, Jie Lu, Hongqi Zhang
Summary: TOF-MRA can be used as a first-line noninvasive imaging modality during follow-up, especially for patients treated with a pipeline embolization device and coils only, but may not be sufficient for clipped aneurysms.
JOURNAL OF NEUROINTERVENTIONAL SURGERY
(2021)
Review
Chemistry, Physical
Huan Zhang, Xiao Li Liu, Hai Ming Fan
Summary: Magnetic resonance imaging (MRI) has revolutionized medical imaging diagnostics. However, the clinical use of Gd-based contrast agents (CAs) still has limitations, making the development of magnetic nanoparticle-based CAs a promising avenue for research.
Article
Medicine, General & Internal
Francesco Secchi, Davide Capra, Caterina Beatrice Monti, Nazanin Mobini, Maria Del Mar Galimberti Ortiz, Santi Trimarchi, Daniela Mazzaccaro, Paolo Righini, Giovanni Nano, Francesco Sardanelli
Summary: This study aimed to investigate the use of unenhanced magnetic resonance imaging (MRI) as a safe and highly sensitive tool for endoleak screening in patients treated with endovascular aneurysm repair (EVAR). The study found that unenhanced MRI has perfect sensitivity for endoleak detection, but subpar specificity.
Article
Cardiac & Cardiovascular Systems
Angela Lopez-Sainz, Laia Mila, Jose Rodriguez-Palomares, Javier Limeres, Chiara Granato, Lucia La Mura, Ana Sabate, Andrea Guala, Laura Gutierrez, Laura Galian-Gay, Augusto Sao-Aviles, Sergi Bellmunt, Rafael Rodriguez, Hug Cuellar-Calabria, Albert Roque, Ignacio Ferreira-Gonzalez, Artur Evangelista, Gisela Teixido-Tura
Summary: This study revealed that aortic branch aneurysms are present in approximately one-quarter of patients with MFS, are associated with patient age and aortic dilation, and independently predict the need for aortic surgery.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Oncology
Natalie Baum, Ralf Fliegert, Andreas Bauche, Julia Hambach, Stephan Menzel, Friedrich Haag, Peter Bannas, Friedrich Koch-Nolte
Summary: Multiple myeloma is a hematological malignancy characterized by antibody-producing plasma cells in the bone marrow. CD38-specific antibodies, like daratumumab, can induce cytotoxicity against tumor cells, but there is still a need for improved CD38 inhibitory antibodies to target multiple myeloma effectively.
Correction
Cardiac & Cardiovascular Systems
Aleksander Kosmala, Philipp Gruschwitz, Simon Veldhoen, Andreas Max Weng, Bernhard Krauss, Thorsten Alexander Bley, Bernhard Petritsch
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Corona Metz, David Boeckle, Julius Frederik Heidenreich, Andreas Max Weng, Thomas Benkert, Gotz Ulrich Grigoleit, Thorsten Bley, Herbert Koestler, Simon Veldhoen
Summary: This study evaluated the feasibility of using non-contrast-enhanced three-dimensional ultrashort echo time (3D-UTE) MRI for pulmonary imaging in immunocompromised patients during hematopoietic stem cell transplantation (HSCT). The results showed that 3D-UTE MRI had high sensitivity and specificity for pleural effusions and consolidations, but lower diagnostic performance for ground glass opacities. Compared to T2w imaging, 3D-UTE MRI was rated as having at least equivalent quality in depicting assessed pathologies, with superiority in consolidations and ground glass opacities.
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
(2022)
Article
Orthopedics
Henner Huflage, Tabea Fieber, Christian Farber, Jonas Knarr, Simon Veldhoen, Martin C. Jordan, Fabian Gilbert, Thorsten Alexander Bley, Rainer H. Meffert, Jan-Peter Grunz, Jonas Schmalzl
Summary: This study compared the interobserver reliability and diagnostic confidence of the AO/OTA classification and the Euler and Ruedi classification system in scapula fractures. The results showed that the AO/OTA classification was suitable for intra-articular fractures with glenoid involvement, while the Euler and Ruedi classification system was superior for extra-articular fractures involving only the scapula body, spine, acromion, and coracoid process.
BMC MUSCULOSKELETAL DISORDERS
(2022)
Article
Oncology
Inka Ristow, Frederic Madesta, Lennart Well, Farzad Y. Shenas, Felicia Wright, Isabel Molwitz, Said Farschtschi, Peter Bannas, Gerhard Adam, Victor F. Mautner, Rene Werner, Johannes Salamon
Summary: This study demonstrates that machine-learning classification using MRI-based radiomics features allows sensitive and specific differentiation of benign peripheral nerve sheath tumors (BPNST) and malignant peripheral nerve sheath tumors (MPNST) in patients with neurofibromatosis type 1 (NF1). The feature expression of premalignant atypical tumors (ANF) falls between that of benign and malignant tumors, suggesting the biological plausibility of these radiomics features.
Review
Medicine, General & Internal
Sebastian Weiss, Valentin Weisse, Alexander Korthaus, Peter Bannas, Karl-Heinz Frosch, Carsten Schlickewei, Alexej Barg, Matthias Priemel
Summary: Appendicular soft tissue lymphoma is a rare disease often misdiagnosed as soft tissue sarcoma. There is limited research on the MRI characteristics of ASTL, and the results are inconsistent. This study systematically reviewed the clinical presentations and MRI characteristics of ASTL described in the current literature.
Article
Medicine, General & Internal
Alonja Reiter, Katharina Trumm, Tobias M. Ballhause, Sebastian Weiss, Karl-Heinz Frosch, Alexander Korthaus, Ulrich Bechler, Anna Dupree, Andreas Luebke, Peter Bannas, Carsten W. Schlickewei, Matthias H. Priemel
Summary: Intramuscular myxomas (IMMs) are rare benign tumors with limited evidence and guidelines regarding diagnosis and treatment. This study analyzed 38 patients retrospectively and evaluated their diagnostic and therapeutic procedures. The findings showed that IMMs predominantly occurred in middle-aged women, mostly in the extremities, with the lower extremity being the most affected. The average size of IMMs was 5.0 cm and MRIs were commonly performed for imaging. Incision biopsies were effective in obtaining the right histopathological diagnosis. Surgical resection was successful in 89.5% of cases, and postoperative complications requiring revision were reported in 8.8% of cases. Recurrences and degenerations of IMMs were not observed.
Article
Radiology, Nuclear Medicine & Medical Imaging
Theresa Sophie Patzer, Jan-Peter Grunz, Henner Huflage, Nora Conrads, Simon Veldhoen, Jonas Schmalzl, Lenhard Pennig, Thorsten Alexander Bley, Karsten Sebastian Luetkens, Andreas Steven Kunz
Summary: The study found that CBCT showed superior accuracy in diagnosing postoperative complications compared to standard X-ray images, more reliably detecting issues such as screw dislocation, implant loosening, fragment displacement, and delayed healing.
EUROPEAN JOURNAL OF RADIOLOGY
(2022)
Article
Oncology
Natalia Bogdanova, Hoda Radmanesh, Dhanya Ramachandran, Anne Caroline Knoechelmann, Hans Christiansen, Thorsten Derlin, Christoph Alexander Joachim von Klot, Roland Merten, Christoph Henkenberens
Summary: This study aims to evaluate the prognostic value of liquid biopsies in patients with oligometastatic prostate cancer relapse in order to determine the benefit of salvage radiotherapy. The study found significant correlations between the relative transcript levels of specific genes and clinicopathological parameters, as well as treatment outcomes. Therefore, liquid biopsies have the potential to serve as predictive examination methods prior to salvage radiotherapy.
Article
Radiology, Nuclear Medicine & Medical Imaging
Corona Metz, Andreas Max Weng, David Boeckle, Julius Frederik Heidenreich, Anne Slawig, Thomas Benkert, Sabrina Kraus, Herbert Koestler, Simon Veldhoen
Summary: This study compares the diagnostic performance of free-breathing three-dimensional ultrashort echo time (UTE) sequences with different trajectories in pulmonary imaging of immunocompromised patients. It finds that both sequences have similar diagnostic performance and can accurately detect inflammatory lung pathologies.
Article
Radiology, Nuclear Medicine & Medical Imaging
C. Metz, A. M. Weng, J. F. Heidenreich, A. Slawig, T. Benkert, H. Koestler, S. Veldhoen
Summary: This study evaluated the reproducibility of functional lung imaging using non-contrast enhanced multi breath-hold 3D-UTE MRI. The results showed that this method allows for highly reliable ventilation imaging.
MAGNETIC RESONANCE IMAGING
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Julius Frederik Heidenreich, Philipp Josef Kuhl, Jan-Peter Grunz, Robin Hendel, Corona Metz, Andreas Max Weng, Thomas Benkert, Helge Hebestreit, Thorsten Alexander Bley, Herbert Kostler, Simon Veldhoen
Summary: Noncontrast 3D UTE lung MRI functional parameters can be used to assess lung function over time in patients with CF and can add regional information to established global parameters, such as LCI.
Review
Radiology, Nuclear Medicine & Medical Imaging
Inka Ristow, Christoph Riedel, Alexander Lenz, Lennart Well, Gerhard Adam, Giuseppe Panuccio, Tilo Kolbel, Peter Bannas
Summary: Radiological imaging plays a vital role in the diagnosis and monitoring of AAA patients. Ultrasound is the main imaging modality for screening and surveillance. Contrast-enhanced CT angiography is considered the gold standard for preoperative imaging and treatment planning. Non-contrast MR angiography techniques provide accurate determination of aortic diameters, which is crucial for diameter-based surgical treatment guidelines. 3D imaging with multiplanar reformation and automatic centerline positioning enables more accurate assessment of the maximum aortic diameter. Modern imaging techniques like 4D flow MRI have the potential to improve individualized risk stratification in AAA patients.
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
(2023)
Article
Pediatrics
Corona Metz, Andrea Schmid, Simon Veldhoen
Summary: This study found that there was a significant increase in the number of MRI and CT scans, as well as the rates of complications, detected streptococcal infections, and surgeries among children with upper airway infections during the 2022/2023 winter season compared to the previous five winter seasons. However, there was a significant decrease in these parameters during the first complete pandemic winter season in Europe (2020/2021) compared to the pre-pandemic, second pandemic, and post-pandemic winter seasons.
PEDIATRIC RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andrea Schmid, Anna-Maria Lois, Corona Metz, Jan-Peter Grunz, Simon Veldhoen
Summary: This study found that fractures may lead to the occurrence of multipartite epicondyles, especially the lateral epicondyle. The multipartition of the medial epicondyle was only observed in patients with a history of elbow fractures.
EUROPEAN RADIOLOGY
(2022)