Article
Engineering, Biomedical
N. W. Marshall, L. Cockmartin, H. Bosmans
Summary: Part II of this study presents constancy tests for artifacts, image uniformity, exposure time, and phantom-based dosimetry in mammography systems with contrast enhanced mammography (CEM) capability. The study evaluates the uniformity and signal-to-noise ratio of images taken with different phantom compositions and assesses the mean glandular dose (MGD) as a function of simulated breast thickness. The results show that image uniformity is superior for low energy images compared to high energy images, and the MGD is lower for high energy images than for low energy images.
PHYSICS IN MEDICINE AND BIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Ya-Chun Tang, Yun-Chung Cheung
Summary: Contrast-enhanced mammography-guided biopsy (CEM-Bx) is a novel technique for diagnosing suspicious enhanced lesions that was commercialized for clinical application in 2021. This study aimed to evaluate the procedural performance and preliminary outcomes of CEM-Bx performed in our hospital between September 2021 and June 2022. Data from 12 women who underwent CEM-Bx were reviewed, including demographic characteristics, procedural details, biopsy success rate, histopathological diagnosis, and average glandular dose (AGD). The study found that CEM-Bx had a 100% success rate in diagnosing contract-enhanced lesions, with a malignancy rate of 66.7%.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yonggeng Goh, Ching Wan Chan, Premilla Pillay, Herng-Sheng Lee, Huay-Ben Pan, Bao-Hui Hung, Swee Tian Quek, Chen-Pin Chou
Summary: This study developed an ADS model for risk assessment of tomosynthesis-detected architectural distortion (AD) lesions based on characteristics of contrast-enhanced digital mammography. The features of CEDM can be used to predict the malignant risk of AD lesions.
EUROPEAN RADIOLOGY
(2021)
Article
Multidisciplinary Sciences
L. M. F. H. Neeter, H. P. J. Raat, S. D. Meens-Koreman, R. S. A. van Stiphout, S. M. E. C. Timmermans, K. M. Duvivier, M. L. Smidt, J. E. Wildberger, P. J. Nelemans, M. B. Lobbes
Summary: The study aimed to evaluate the diagnostic performance of contrast-enhanced mammography (CEM) on an alternative vendor's system, showing improvements in sensitivity and specificity compared to low-energy images. The results suggest that performing CEM on the tested system leads to increased accuracy, similar to findings from studies conducted on other vendor's systems.
SCIENTIFIC REPORTS
(2021)
Review
Oncology
Mindy L. Yang, Chandni Bhimani, Robyn Roth, Pauline Germaine
Summary: Contrast-enhanced mammography (CEM) has become a widely used modality in breast imaging, showing high diagnostic performance in cancer detection. It is comparable to MRI in sensitivity with lower false positive rates. Familiarity with CEM and its implementation is of great clinical significance, as it can be used for screening dense breasts as well as staging known breast malignancies.
Article
Radiology, Nuclear Medicine & Medical Imaging
Giulia Bicchierai, Simone Busoni, Paolo Tortoli, Silvia Bettarini, Federica Di Naro, Diego De Benedetto, Elena Savi, Chiara Bellini, Vittorio Miele, Jacopo Nori
Summary: This retrospective study compares the radiation dose received during CEDM, short and long protocol (CEDM SP and CEDM LP), with dose received during DM and DBT. The results show that CEDM SP results in higher radiation exposure compared with conventional DM and DBT but lower than the Combo mode. The dose administered during the CEDM SP is lower in patients with dense breasts regardless of their size.
ACADEMIC RADIOLOGY
(2022)
Review
Oncology
Federica Vasselli, Alessandra Fabi, Francesca Romana Ferranti, Maddalena Barba, Claudio Botti, Antonello Vidiri, Silvia Tommasin
Summary: The aim of this study was to investigate the association between contrast-enhanced spectral mammography (CESM) findings and prognostic factors in breast cancer. The results showed that CESM enhancement is associated with the proliferation of tumoral cells and the expression of estrogen and progesterone receptors. The study suggests that CESM has the potential for improving breast cancer diagnostics, but further research is needed.
FRONTIERS IN ONCOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Rossano Girometti, Anna Linda, Paola Conte, Michele Lorenzon, Isabella De Serio, Katerina Jerman, Viviana Londero, Chiara Zuiani
Summary: The study found that preoperative contrast-enhanced spectral mammography (CEM) had better ability to detect additional cancer lesions in breast cancer patients compared to digital mammography plus digital breast tomosynthesis (DM + DBT), especially in dense breasts. CEM and DM + DBT showed similar performance in cancer size assessment.
Review
Radiology, Nuclear Medicine & Medical Imaging
Maxine S. Jochelson, Marc B. Lobbes
Summary: Contrast-enhanced mammography (CEM) is a promising alternative to contrast-enhanced breast MRI, offering improved accuracy in vascular imaging while reducing examination costs. It has shown positive outcomes in diagnosing breast lesions and screening, as well as in preoperative staging and monitoring response to chemotherapy in breast cancer patients. Early results also indicate potential benefits in screening high-risk women for breast cancer, although there are slight risks and increased radiation dose associated with CEM.
Article
Medicine, General & Internal
Giuliana Moffa, Francesca Galati, Roberto Maroncelli, Veronica Rizzo, Federica Cicciarelli, Marcella Pasculli, Federica Pediconi
Summary: The aim of this study was to compare the diagnostic performance of contrast-enhanced mammography (CEM) versus digital mammography (DM) combined with breast ultrasound (BUS) in women with dense breasts. The results showed that CEM had better sensitivity, specificity, positive predictive value, negative predictive value, and accuracy compared to DM and BUS. Therefore, CEM has a better diagnostic performance for women with dense breasts.
Article
Radiology, Nuclear Medicine & Medical Imaging
Kathryn Zamora, Elizabeth Allen, Brittany Hermecz
Summary: This article discusses the indications for CESM, focusing on imaging interpretation. CESM has comparable sensitivity and accuracy to MRI, but is less time consuming and less expensive, making it increasingly utilized for breast cancer evaluation and diagnosis. Ongoing research is exploring the role of CESM in asymptomatic screening for breast cancer.
Article
Radiology, Nuclear Medicine & Medical Imaging
Julie Sogani, Victoria L. Mango, Delia Keating, Janice S. Sung, Maxine S. Jochelson
Summary: Contrast-enhanced mammography (CEM) combines conventional mammography with iodinated contrast material to improve cancer detection. CEM has comparable performance to breast MRI and can be useful for various indications in clinical practice.
Article
Radiology, Nuclear Medicine & Medical Imaging
Gisella Gennaro, Enrica Baldan, Elisabetta Bezzon, Francesca Caumo
Summary: This study evaluated the effectiveness of a new algorithm in reducing artifacts in dual-energy subtraction contrast-enhanced mammography images while preserving lesion contrast enhancement. The new algorithm successfully eliminated/reduced different types of artifacts, and showed equivalent results in maintaining lesion contrast enhancement compared to the standard algorithm.
INSIGHTS INTO IMAGING
(2022)
Article
Medicine, General & Internal
Gisella Gennaro, Melissa L. Hill, Elisabetta Bezzon, Francesca Caumo
Summary: Contrast-enhanced mammography may play an important role in personalized breast cancer screening models, especially for women at high risk or with dense breasts. Volumetric breast density measured from low-energy contrast-enhanced spectral mammography showed no significant difference compared to density measurements from standard digital mammography or tomosynthesis. The differences in volumetric breast density were associated with various independent variables, primarily related to breast positioning.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Oncology
Natalia Siminiak, Anna Pasiuk-Czepczynska, Antonina Godlewska, Piotr Wojtys, Magdalena Olejnik, Joanna Michalak, Piotr Nowaczyk, Pawel Gajdzis, Dariusz Godlewski, Marek Ruchala, Rafal Czepczynski
Summary: This study evaluated the diagnostic performance of CEM and DBT in women recalled from a breast cancer screening program. The results showed that CEM and DBT had similar diagnostic accuracy and outperformed FFDM. CEM had a sensitivity of 97% and DBT had a sensitivity of 100%.
FRONTIERS IN ONCOLOGY
(2022)