Review
Medicine, General & Internal
Filippo Cademartiri, Antonella Meloni, Laura Pistoia, Giulia Degiorgi, Alberto Clemente, Carmelo De Gori, Vincenzo Positano, Simona Celi, Sergio Berti, Michele Emdin, Daniele Panetta, Luca Menichetti, Bruna Punzo, Carlo Cavaliere, Eduardo Bossone, Luca Saba, Riccardo Cau, Ludovico La Grutta, Erica Maffei
Summary: The photon-counting detector (PCD) is a new technology that provides significant benefits for cardiac and coronary artery imaging. Compared with conventional CT, PCCT has improved capabilities such as multi-energy capability, increased spatial resolution, reduced radiation exposure, and optimized use of contrast agents. It also overcomes limitations of traditional CCT/CCTA, such as reducing artifacts and enabling more precise assessment of stenosis and plaque characteristics. PCCT also has potential applications in characterizing myocardial tissue using a double-contrast agent.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Giovanni Foti, Ronaldo Silva, Niccolo Faccioli, Alessandro Fighera, Rossella Menghini, Arianna Campagnola, Giovanni Carbognin
Summary: In a selected, high-prevalence population, VP-DECT is considered an accurate imaging tool for diagnosing PE compared to CTPA. The sensitivity of VP-DECT images in per-patient analysis was 90.0%, with 100% specificity; while in per-lobe analysis, sensitivity ranged from 100% for the right lower lobe to 50% for the left upper lobe.
EUROPEAN RADIOLOGY
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
David C. Rotzinger, Salim A. Si-Mohamed, Jerome Yerly, Sara Boccalini, Fabio Becce, Loic Boussel, Reto A. Meuli, Salah D. Qanadli, Philippe C. Douek
Summary: The study demonstrates that VMI outperform conventional CT in terms of accuracy and precision in vitro, while low-keV VMI allows for a 40% iodine dose reduction in vivo while maintaining diagnostic image quality and improving the CNR between lumen versus fat and muscle.
EUROPEAN RADIOLOGY
(2021)
Article
Instruments & Instrumentation
Wen Qian, Wangyan Liu, Yinsu Zhu, Jun Wang, Yang Chen, Haoyu Meng, Leilei Chen, Yi Xu, Xiaomei Zhu
Summary: The study found that image quality and diagnostic accuracy of CT-derived fractional flow reserve (FFRCT) are affected by heart rate and coronary artery calcium score.
JOURNAL OF X-RAY SCIENCE AND TECHNOLOGY
(2021)
Article
Medicine, General & Internal
Matthias Eberhard, Victor Mergen, Kai Higashigaito, Thomas Allmendinger, Robert Manka, Thomas Flohr, Bernhard Schmidt, Andre Euler, Hatem Alkadhi
Summary: The study evaluated the accuracy of coronary artery calcium scoring on a dual-source photon-counting detector CT. Results showed that VMI reconstructions provided accurate CAC scoring at different radiation dose levels.
Article
Radiology, Nuclear Medicine & Medical Imaging
Meng-Meng Yu, Wu-Xu Zuo, Xin Zhao, Xiang-Lin Tang, Yin-Yin Chen, Li-Li Dong, Xian-Hong Shu, Hang Jin, Meng-Su Zeng
Summary: This study investigated the prognostic value of coronary CT angiography (CCTA) in heart failure patients with preserved ejection fraction (HFpEF). The results showed a higher prevalence of coronary atherosclerosis in the HFpEF group compared to the non-HFpEF group. During the follow-up period, participants with HFpEF exhibited a higher risk of major adverse cardiovascular events (MACEs) in different CAD-RADS categories. CAD-RADS = 1-2 increased the risk of nonfatal myocardial infarction, while CAD-RADS ≥ 3 were associated with cardiovascular mortality and hospitalization due to heart failure.
EUROPEAN RADIOLOGY
(2023)
Article
Medicine, General & Internal
Marian Ondrejkovic, Dusan Salat, Daniel Cambal, Andrej Klepanec
Summary: This study aimed to evaluate the impact of high and irregular heart rate on the image quality and radiation exposure in CT coronary angiography using a 256-row, 16cm wide detector CT system. The results showed that patients with a regular heart rate had better image quality and lower radiation dose compared to patients with an irregular heart rhythm. The use of a CT scanner with a 16cm wide detector enabled low radiation exposure even at high heart rates or irregular heart rhythms.
Article
Radiology, Nuclear Medicine & Medical Imaging
Leening P. Liu, Nadav Shapira, Andrew A. Chen, Russell T. Shinohara, Pooyan Sahbaee, Mitchell Schnall, Harold Litt, Peter B. Noel
Summary: This study compared the image characteristics of a first-generation dual-source photon-counting computed tomography (PCCT) and a dual-source dual-energy CT (DECT) scanner at ultra-low radiation dose levels. The results showed that PCCT had high precision in Hounsfield unit (HU) measurements at various radiation dose levels, outperforming DECT at low doses and significantly reducing electronic background noise.
EUROPEAN RADIOLOGY
(2022)
Article
Medicine, General & Internal
Tommaso D'Angelo, Ludovica R. M. Lanzafame, Antonino Micari, Alfredo Blandino, Ibrahim Yel, Vitali Koch, Leon D. Gruenewald, Thomas J. Vogl, Christian Booz, Giuseppe M. Bucolo, Maria Teresa Cannizzaro, Giorgio Ascenti, Silvio Mazziotti
Summary: This study investigates the use of monoenergetic reconstructions in coronary CT angiography (CCTA) obtained from a dual-layer spectral detector computed tomography (DLCT) system. The results show that the 40 keV monoenergetic images provide improved image quality without affecting the quantitative assessment of coronary stenoses.
Article
Radiology, Nuclear Medicine & Medical Imaging
Lukas Lenga, Marvin Lange, Simon S. Martin, Moritz H. Albrecht, Christian Booz, Ibrahim Yel, Christophe T. Arendt, Thomas J. Vogl, Doris Leithner
Summary: The study compared the radiation dose and image quality of head and neck CT scans using second- and third-generation DSCT systems, finding that third-generation DSCT had the highest dose efficiency, with DECT Group D showing superior performance in figure-of-merit/contrast-to-noise ratio analysis.
BRITISH JOURNAL OF RADIOLOGY
(2021)
Article
Medicine, General & Internal
Milan Vecsey-Nagy, Adam Levente Jermendy, Marton Kolossvary, Borbala Vattay, Melinda Boussoussou, Ferenc Imre Suhai, Alexisz Panajotu, Judit Csore, Sarolta Borzsak, Daniele Mariastefano Fontanini, Csaba Csobay-Novak, Bela Merkely, Pal Maurovich-Horvat, Balint Szilveszter
Summary: This study compared the amount of motion artifacts in coronary CT angiography images acquired using a dedicated cardiac CT scanner and a conventional multidetector CT scanner. The results showed that the dedicated cardiac CT scanner yielded fewer motion artifacts, allowing for optimal image quality even at high heart rates.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Jia Zhou, Chunjie Li, Hong Zhang, Chang Liu, Junjie Yang, Jia Zhao, Yonghong Hou, Yahang Tan, Hao Wang, Yaoshuang Li, Cun Xie, Minghui Wang, Chengjian Wang, Enyuan Zhang, Shuo Wang, Pengyu Zhao, Dongkai Shan, Shuo Liang, Yufan Gao, Yong Huo, Hongliang Cong, Zhigang Guo, Yundai Chen
Summary: This study retrospectively assessed the association between the appropriateness of post-CCTA management according to CAD-RADS 2.0 and clinical outcomes. The results showed that appropriate management was associated with a lower risk of major adverse cardiovascular events and a more prudent use of invasive coronary angiography.
Article
Radiology, Nuclear Medicine & Medical Imaging
Natasa Javorszky, Balint Homonnay, Gary Gerstenblith, David Bluemke, Peter Kiss, Mihaly Torok, David Celentano, Hong Lai, Shenghan Lai, Marton Kolossvary
Summary: This study developed an open-source deep learning model for segmenting coronary plaques on coronary CT angiography. The model showed excellent performance in quantifying plaque volumes in both the test set and an external dataset, and transfer learning further improved the accuracy of the model.
EUROPEAN RADIOLOGY
(2022)
Article
Multidisciplinary Sciences
Leening P. Liu, Nadav Shapira, Pooyan Sahbaee, Grace J. Gang, Friedrich D. Knollman, Marcus Y. Chen, Harold I. Litt, Peter B. Noel
Summary: In this study, the stability of spectral results in first-generation clinical dual-source photon-counting CT (PCCT) was evaluated under different heart rates, acquisition modes, and cardiac phases. The results demonstrated consistent spectral results across different acquisition parameters and cardiac phases, highlighting the additional benefit of spectral results in increasing confidence in cardiovascular diagnostics.
SCIENTIFIC REPORTS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Christian Roest, Reina W. Kloet, Maria J. Lamers, Derya Yakar, Thomas C. Kwee
Summary: This study explored the technical feasibility of focused view CTA for selectively visualizing stroke-related arteries. By training a deep learning algorithm, brain and extracranial arteries were selectively extracted from 141 CTA examinations for acute ischemic stroke evaluation. The visibility of anatomic structures was assessed and the results showed that focused view CTA had improved visibility compared to unmodified CTA.
EUROPEAN RADIOLOGY
(2023)