Article
Cardiac & Cardiovascular Systems
Domenico Spinelli, Fred A. Weaver, Ali Azizzadeh, Gregory A. Magee, Gabriele Piffaretti, Filippo Benedetto, Charles C. Miller, Harleen K. Sandhu, Dennis R. Gable, Santi Trimarchi
Summary: The study aimed to analyze the outcomes of thoracic endovascular aortic repair for complicated and uncomplicated acute type B aortic dissections. The data from WL Gore's Global Registry for Endovascular Aortic Treatment showed that the 30-day mortality and perioperative complications were equally low for both complicated and uncomplicated type B aortic dissections, and the midterm outcome was positive.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Medicine, General & Internal
Zhiqiang Dong, He Yang, Gang Li, Xinyang Xu, Hong Liu, Jiaxi Gu, Minghui Li, Weidong Gu, Yongfeng Shao, Buqing Ni
Summary: This study collected clinical and imaging data of patients treated with TEVAR for TBAD, and found that preoperative partial thrombosis of the FL and an increase in the maximum aortic diameter are strongly associated with late aortic expansion, suggesting that additional interventions of the FL may improve the prognosis of high-risk patients.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Li Cheng, Dongqiao Xiang, Shan Zhang, Chuansheng Zheng, Xiaoyan Wu
Summary: In this retrospective study, reintervention after TEVAR was observed in 11.3% of patients with uncomplicated TBAD, and the main reasons included endoleak, aneurysmal dilation, and dissection progression. Larger initial aortic diameter and excessive proximal landing zone oversizing were identified as significant risk factors for reintervention. Reintervention did not significantly affect long-term survival rates.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Surgery
Daniel J. Torrent, Graeme E. McFarland, Grace Wang, Mahmoud Malas, Benjamin J. Pearce, Victoria Aucoin, Dan Neal, Emily L. Spangler, Zdenek Novak, Salvatore T. Scali, Adam W. Beck
Summary: This analysis examined the correlation between the timing of TEVAR for UATBAD patients and postoperative complications. While timing did not predict mortality or long-term complications, there was a higher risk of reintervention within 1-14 days post-operation. This suggests the importance of further study on optimal timing for intervention in TEVAR trials.
JOURNAL OF VASCULAR SURGERY
(2021)
Review
Surgery
Erin C. Saricilar, Kiraati Patel, Raleene Gatmaitan, Vikram Puttaswamy
Summary: This systematic review found that early intervention in Type B aortic dissections can improve aorta related events in the one year follow up period without changing the mortality rate compared to late intervention. Therefore, performing TEVAR surgery within 3 to 14 days after symptom onset is both safe and beneficial.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2023)
Review
Cardiac & Cardiovascular Systems
Mohamad Bashir, Matti Jubouri, Sven Z. C. P. Tan, Damian M. Bailey, Bashi Velayudhan, Idhrees Mohammed, Randolph H. L. Wong, Martin Czerny, Edward P. Chen, Leonard N. Girardi, Joseph S. Coselli, Ian Williams
Summary: This review aims to delineate the literature defining the intervention parameters for UnCoTBAD. While UnCoTBAD is considered uncomplicated, close monitoring and potentially more complex interventions may be required for certain high-risk features.
JOURNAL OF CARDIAC SURGERY
(2022)
Review
Cardiac & Cardiovascular Systems
WenXin Zhao, Yang Yang, ZhiYuan Wu, ZuoGuan Chen, YongPeng Diao, Yong Lan, YongJun Li
Summary: This study conducted a meta-analysis to evaluate the optimal timing for endovascular repair of acute versus subacute uncomplicated Type B Aortic Dissection. The results showed that the acute group had higher rates of 30-day complications, mortality, and 1-year mortality compared to the subacute group. Therefore, endovascular repair at the subacute phase appears to be more favorable than the acute phase.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Surgery
Antony Aziz, Hannah O'Donnell, Donald G. Harris, Hee Soo Jung, Paul DiMusto
Summary: This study aimed to develop a standardized medical management protocol for uncomplicated acute type B aortic dissection (TBAD) and found that implementing the protocol reduced resource utilization and costs without compromising patient outcomes. The protocol focused on early initiation of oral medications, weaning of anti-hypertensive infusions, and frequent assessment for de-escalation of care. Post-protocol patients had shorter hospital stays, decreased costs, and required less antihypertensive medication at discharge. There was no significant difference in 30-day mortality.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Cardiac & Cardiovascular Systems
E. Hope Weissler, Oyomoare L. Osazuwa-Peters, Melissa A. Greiner, N. Chantelle Hardy, Panagiotis Kougias, Sean M. O'Brien, Daniel B. Mark, W. Schuyler Jones, Eric A. Secemsky, Andrew M. Vekstein, Sherene Shalhub, Firas F. Mussa, Manesh R. Patel, Sreekanth Vemulapalli
Summary: This study aimed to assess whether initial TEVAR following uTBAD is associated with reduced mortality or morbidity compared with medical therapy alone. The results showed that initial TEVAR was not associated with improved mortality or reduced hospitalizations or aortic interventions over a period of 5 years, but in a sensitivity analysis that included deaths within the first 30 days, initial TEVAR was associated with lower mortality.
Review
Cardiac & Cardiovascular Systems
Alexander Geragotellis, Mohammed Al-Tawil, Matti Jubouri, Sven Z. C. P. Tan, Ian Williams, Mohamad Bashir
Summary: There is currently a lack of clear clinical guidelines for selecting unTBAD patients for TEVAR based on risk stratification. However, certain clinical, laboratory, and morphological parameters can be used to identify high-risk patients. Further advancements in biomarkers and imaging techniques are expected to optimize risk-stratified treatment protocols.
JOURNAL OF CARDIAC SURGERY
(2022)
Article
Medicine, General & Internal
Anas Abu Bokha, Chen-He Li, Ming-Yang Song, Xiang Wei, Rui Li
Summary: The study aimed to investigate the predictive value of preoperative neutrophils in aortic dissection patients undergoing TEVAR. The results showed that increased CD10- immature neutrophils may act as a potential biomarker for adverse outcomes in TBAD patients.
INTERNATIONAL JOURNAL OF GENERAL MEDICINE
(2023)
Article
Surgery
Tomoki Cho, Keiji Uchida, Shota Yasuda, Ryo Izubuchi, Shotaro Kaneko, Atsushi Matsumoto, Makoto Ikematsu, Sho Kakuta
Summary: This study aimed to examine the mid-term results of pre-emptive thoracic endovascular aortic aneurysm repair (TEVAR) for uncomplicated type B aortic dissection. The study found that zone 2 landing was an independent risk factor for aortic enlargement after pre-emptive TEVAR.
JOURNAL OF ENDOVASCULAR THERAPY
(2023)
Article
Medicine, General & Internal
Joscha Mulorz, Franziska Garcon, Amir Arnautovic, Casper De Somer, Artis Knapsis, Hug Aubin, Felix Fleissner, Julian-Dario Rembe, Malwina Vockel, Alexander Oberhuber, Artur Lichtenberg, Hubert Schelzig, Markus Udo Wagenhaeuser
Summary: This study examines the geometric architecture of the aortic arch and supra-aortic branches in patients with type B aortic dissection (TBAD) compared to non-TBAD patients. The results show significant differences in aortic arch configuration, angles, and inter-vessel distance between TBAD and non-TBAD patients, providing insights into potential risk factors for TBAD development.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Hui-Qiang Gao, Guoqi Li, Hong-Kai Zhang, Lan-Lin Zhang, Shang-Dong Xu
Summary: This study aimed to determine the optimal timing of thoracic endovascular aortic repair (TEVAR) for patients with uncomplicated type B dissections and a smoking history. Data from 308 patients with a smoking history who underwent TEVAR within 90 days were analyzed. The findings suggest that early TEVAR, performed within 9.4 days from onset, may result in better long-term survival for these patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Surgery
Enmin Xie, Fan Yang, Yuan Liu, Ling Xue, Ruixin Fan, Nianjin Xie, Lyufan Chen, Jitao Liu, Jianfang Luo
Summary: The study aimed to evaluate the effect of intervention timing from symptom onset to thoracic endovascular aortic repair (TEVAR) on outcomes in high risk patients with uncomplicated type B aortic dissection (uTBAD). It found that performing TEVAR in the acute phase was associated with a trend toward higher rates of early complications, but long term outcomes were comparable with those of the subacute phase.
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
(2021)
Article
Surgery
Carola M. Wieker, Philipp von Stein, Claudio Bianchini Massoni, Fabian Rengier, Dittmar Boeckler, Philipp Geisbuesch
JOURNAL OF VASCULAR SURGERY
(2019)
Review
Cardiac & Cardiovascular Systems
Fabian Rengier, Claudius Melzig, Thorsten Derlin, Alberto M. Marra, Jens Vogel-Claussen
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2019)
Article
Surgery
Philipp Geisbuesch, Denis Skrypnik, Marius Ante, Michael Trojan, Tom Bruckner, Fabian Rengier, Dittmar Boeckler
JOURNAL OF VASCULAR SURGERY
(2019)
Review
Cardiac & Cardiovascular Systems
Xin Li, Victor Kondray, Sidhartha Tavri, Arjang Ruhparwar, Samuel Azeze, Aritra Dey, Sasan Partovi, Fabian Rengier
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2019)
Article
Radiology, Nuclear Medicine & Medical Imaging
Claudius Melzig, Stefan Woerz, Benjamin Egenlauf, Sasan Partovi, Karl Rohr, Ekkehard Gruenig, Hans-Ulrich Kauczor, Claus Peter Heussel, Fabian Rengier
EUROPEAN RADIOLOGY
(2019)
Review
Radiology, Nuclear Medicine & Medical Imaging
Viktoria Palm, Fabian Rengier, Prabhakar Rajiah, Claus Peter Heussel, Sasan Partovi
ROFO-FORTSCHRITTE AUF DEM GEBIET DER RONTGENSTRAHLEN UND DER BILDGEBENDEN VERFAHREN
(2020)
Article
Cardiac & Cardiovascular Systems
Tilman Leidenberger, Yaron Gordon, Mina Farag, Michael Delles, Augusto Fava Sanches, Matthias A. Fink, Klaus Kallenbach, Hans-Ulrich Kauczor, Fabian Rengier
ANNALS OF THORACIC SURGERY
(2020)
Article
Engineering, Biomedical
Michal Buk, Fabian Rengier, Theresa Mokry, Johannes Riffel, Evangelos Giannitsis, Lars Kihm, Hana Malikova, Hans-Ulrich Kauczor, Oyunbileg von Stackelberg, Tim Frederik Weber
Summary: This study validated the diagnostic yield and appropriateness of CTPA examinations according to the ESC guidelines. The results showed a high diagnostic accuracy when using sGS and D-dimer blood tests for assessment. However, there was a notable discrepancy between the data transferred to the CTPA request forms and the full clinical documentation, making it challenging for clinical decision making.
BIOMEDICAL PAPERS-OLOMOUC
(2021)
Review
Cardiac & Cardiovascular Systems
David Sin, Gordon McLennan, Fabian Rengier, Ihab Haddadin, Gustavo A. Heresi, John R. Bartholomew, Matthias A. Fink, Dustin Thompson, Sasan Partovi
Summary: The manuscript discusses the application of CT pulmonary angiography, ventilation-perfusion scan, and magnetic resonance angiography in detecting acute pulmonary embolism and planning endovascular therapy. Each imaging modality offers unique advantages and is suitable for different patient populations who may not be candidates for CT pulmonary angiography.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2021)
Article
Surgery
Dmitriy I. Dovzhanskiy, Moritz S. Bischoff, Christopher D. Wilichowski, Fabian Rengier, Anna Klempka, Dittmar Boeckler
LANGENBECKS ARCHIVES OF SURGERY
(2020)
Review
Cardiac & Cardiovascular Systems
Omar Shwaiki, Basem Rashwan, Matthias A. Fink, Levester Kirksey, Sameer Gadani, Karunakaravel Karuppasamy, Claudius Melzig, Dustin Thompson, Giuseppe D'Amico, Fabian Rengier, Sasan Partovi
Summary: Peripheral extremity CTA has gained popularity for noninvasive imaging of arterial vasculature in patients with PAD, offering rapid and high-resolution imaging with reduced contrast and radiation exposure. This technique is effective for delineating the arterial tree, assessing atherosclerotic disease, and differentiating between acute and chronic changes.
INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING
(2021)
Article
Medicine, General & Internal
Matthias A. Fink, Sibylle Stoll, Claudius Melzig, Andrea Steuwe, Sasan Partovi, Dittmar Boeckler, Hans-Ulrich Kauczor, Fabian Rengier
Summary: The purpose of this study was to analyze the image quality and radiation dose of BMI-adapted low-radiation and low-iodine dose CTA of the thoracoabdominal aorta in obese and non-obese patients. The results showed that the BMI-adapted CTA method provided diagnostic image quality in both obese and non-obese patients, with better results in females and the elderly.
Article
Medicine, General & Internal
Simon Dubler, Michael Etringer, Markus A. Weigand, Thorsten Brenner, Stefan Zimmermann, Paul Schnitzler, Bettina Budeus, Fabian Rengier, Paulina Kalinowska, Yuan Lih Hoo, Christoph Lichtenstern
Summary: This study evaluated the outcome relevance of adequately treated putative invasive pulmonary aspergillosis (pIPA) in critically ill patients. The results showed that adequately treated pIPA did not increase the risk of death or unfavourable outcomes.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Carola Marie Hoffmann-Wieker, Artur Rebelo, Martin Moll, Ulrich Ronellenfitsch, Fabian Rengier, Philipp Erhart, Dittmar Boeckler, Joerg Ukkat
Summary: This study analyzed the association between tumor volume and outcome following surgery for cervical paraganglioma. The results showed that tumor volume is associated with postoperative complications, and MRI/CT volumetry can be used for risk stratification.
Article
Cardiac & Cardiovascular Systems
Florian Lasch, Annika Karch, Armin Koch, Thorsten Derlin, Andreas Voskrebenzev, Tawfik Moher Alsady, Marius M. Hoeper, Henning Gall, Fritz Roller, Sebastian Harth, Dagmar Steiner, Gabriele Krombach, Hossein Ardeschir Ghofrani, Fabian Rengier, Claus Peter Heussel, Ekkehard Gruenig, Dietrich Beitzke, Marcus Hacker, Irene M. Lang, Juergen Behr, Peter Bartenstein, Julien Dinkel, Kai-Helge Schmidt, Karl-Friedrich Kreitner, Thomas Frauenfelder, Silvia Ulrich, Okka W. Hamer, Michael Pfeifer, Christopher S. Johns, David G. Kiely, Andrew James Swift, Jim Wild, Jens Vogel-Claussen
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2020)