Article
Clinical Neurology
Y. Ma, X. Li, Y. Pan, R. Zhao, X. Wang, X. Jiang, S. Li
Summary: Cognitive frailty was found to be associated with falls in older people in a population-based longitudinal study. It may serve as a risk factor for falls, and early screening might be beneficial in fall prevention.
EUROPEAN JOURNAL OF NEUROLOGY
(2021)
Article
Surgery
Jason Diab, Walter Flapper, Benjamin Grave, Mark H. Moore
Summary: High-velocity and high-impact forces can cause life-threatening injuries not limited to the face but also involving other body regions. Associated injuries are more frequent in the elderly, affecting other bodily systems and resulting in longer hospital stays.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY
(2022)
Article
Public, Environmental & Occupational Health
Zhengyue Jing, Jie Li, Pei Pei Fu, Yi Wang, Yemin Yuan, Dan Zhao, Wenting Hao, Caiting Yu, Chengchao Zhou
Summary: This study found that the presence of frailty significantly increases the risk of incurring catastrophic health expenditure among single empty-nest elderly with multimorbidity, especially for those with lower economic status.
INTERNATIONAL JOURNAL FOR EQUITY IN HEALTH
(2021)
Article
Geriatrics & Gerontology
Joe Hollinghurst, Helen Daniels, Richard Fry, Ashley Akbari, Sarah Rodgers, Alan Watkins, Sarah Hillcoat-Nalletamby, Neil Williams, Silviya Nikolova, David Meads, Andy Clegg
Summary: The study found that the Care&Repair Cymru home adaptation service can identify and reduce the likelihood of falls occurring at home in older people. Factors such as female gender, older age, increased frailty, and deprivation increase the risk of falls, while the odds of falling decrease post-intervention.
Article
Multidisciplinary Sciences
Manuel Abbas, Majd Saleh, Dominique Somme, Regine Le Bouquin Jeannes
Summary: The use of telemonitoring solutions via wearable sensors is believed to have a major impact on the prevention and treatment of physical weakening in older adults. This pilot study investigated the effectiveness of data-driven systems to characterize older individuals with impaired physical function, utilizing a fully automated process that extracted time-domain features from 24-hour files of data. Machine learning classifiers were then used to distinguish frail from non-frail subjects, with an accuracy of up to 93.51%. This study highlights the importance of longitudinal research and may serve as a foundation for future monitoring systems.
Article
Public, Environmental & Occupational Health
Lijun Fan, Xiang-Yu Hou, Yingyan Liu, Sunan Chen, Qian Wang, Wei Du
Summary: Frailty is a significant predictor for catastrophic health expenditure (CHE) in China, with prefrail or frail older adults associated with higher odds of CHE compared to non-frail individuals. Three components of frailty - weakness, exhaustion, and shrinking - significantly contribute to increased likelihood of CHE, while the other two components - slowness and inactivity - show non-significant effects. The impact of frailty on CHE remains consistent across various socioeconomic-related subgroups. Developing and implementing cost-effective strategies for preventing and managing frailty is crucial to safeguard households from financial catastrophe.
FRONTIERS IN PUBLIC HEALTH
(2021)
Article
Gastroenterology & Hepatology
Eva Roman, Marc Parramon, Montserrat Flavia, Cristina Gely, Maria Poca, Adolfo Gallego, Rosalia Santesmases, Elvira Hernandez, Juan C. Nieto, Eulalia Urgell, Edilmar Alvarado-Tapias, Silvia Vidal, Andreu Ferrero-Gregori, Victor Vargas, Carlos Guarner, German Soriano
Summary: Frailty was more common in outpatients with cirrhosis than in controls, mainly due to decreased muscle strength. Frail cirrhotic patients had a higher likelihood of hospitalization and falls during follow-up, but similar mortality rates.
LIVER INTERNATIONAL
(2021)
Article
Geriatrics & Gerontology
Lucie Rapp, S. Sourdet, M. -H. Lacoste-Ferre
Summary: The study identified a significant association between poor oral health and undernutrition in frail elderly patients, as well as a correlation between deteriorated oral health and frailty. Tongue diseases were found to increase the risk of frailty in patients.
JOURNAL OF NUTRITION HEALTH & AGING
(2021)
Review
Nutrition & Dietetics
Nobuyuki Shirai, Tatsuro Inoue, Masato Ogawa, Masatsugu Okamura, Shinichiro Morishita, Yamamoto Suguru, Atsuhiro Tsubaki
Summary: Falls are a significant social issue for HD patients, as fractures increase their risk of death. Nutritional problems such as frailty, sarcopenia, undernutrition, PEW, and cachexia contribute to the risk of falls and fractures in HD patients. Nutritional therapy is beneficial in preventing falls, and further research is needed to understand the relationships between falls and sarcopenia, cachexia, and PEW.
Article
Geriatrics & Gerontology
Young-Sang Kim, Yao Yao, So-Won Lee, Nicola Veronese, Soo-Jin Ma, Yeon-Hee Park, Sang-Yhun Ju
Summary: This study analyzed panel data from Korean older adults and found that frailty was associated with a higher risk of falls. Social isolation and exhaustion were significantly associated with fall events, while weakness did not show a significant association. These findings suggest that interventions should focus on addressing social and psychological frailty in older adults.
ARCHIVES OF GERONTOLOGY AND GERIATRICS
(2022)
Review
Geriatrics & Gerontology
Z. -C Yang, H. Lin, G. -H Jiang, Y. -H Chu, J. -H Gao, Z. -J Tong, Z-H Wang
Summary: This study aimed to explore the relationship between frailty and falls in older adults and analyze the effect factors of this association. The results showed a significant association between frailty and falls among older adults. Factors such as gender, different frailty assessment tools, areas, level of national economic development, and year of publication may impact this association.
JOURNAL OF NUTRITION HEALTH & AGING
(2023)
Article
Health Care Sciences & Services
Haomiao Li, Jiangyun Chen, Dai Su, Xiwu Xu, Ruibo He
Summary: This study aimed to evaluate the impact of frailty and multimorbidity on catastrophic health expenditure (CHE). The results showed that single chronic disease, multimorbidity, and frailty were associated with a higher risk of CHE. The co-occurrence of frailty with a single chronic disease or multimorbidity, and multimorbidity co-occurring with frailty also increased the risk of CHE.
RISK MANAGEMENT AND HEALTHCARE POLICY
(2023)
Article
Public, Environmental & Occupational Health
Chia-Ming Li, Chih-Hsueh Lin, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Tsai-Chung Li, Cheng-Chieh Lin
Summary: The study found that changes in frailty status among elderly individuals are associated with healthcare utilization and all-cause mortality.
Article
Multidisciplinary Sciences
Hai Minh Vu, Linh Gia Vu, Tung Hoang Tran, Laurent Boyer, Pascal Auquier, Guillaume Fond, Tham Thi Nguyen, Linh Khanh Le, Hoa Thi Do, Huyen Phuc Do, Son Nghiem, Carl A. Latkin, Roger C. M. Ho, Cyrus S. H. Ho
Summary: Falls are a leading cause of death among elderly people, but research on the cost of fall-related injuries in Vietnam is limited. This study estimated the treatment costs and identified associated factors among 405 elderly patients in Thai Binh hospitals. The findings showed that elderly patients with fall-related injuries in Vietnam faced high costs and severe health issues. Strengthening primary healthcare services and communication campaigns are necessary to reduce disease burden and develop effective fall injury prevention strategies.
SCIENTIFIC REPORTS
(2023)
Article
Geriatrics & Gerontology
Kun-Pei Lin, Hsin-Yi Li, Jen-Hau Chen, Feng-Ping Lu, Chiung-Jung Wen, Yi-Chun Chou, Meng-Chen Wu, Ding-Cheng (Derrick) Chan, Yung-Ming Chen
Summary: This study compared the prognostic performance of an electronic frailty index (eFI) with traditional tools in nonfrail and prefrail older adults. The results showed that the eFI system effectively predicted adverse healthcare outcomes in this population over a period of 2 years.
Article
Medicine, General & Internal
Stefano Scabini, Emanuele Romairone, Davide Pertile, Andrea Massobrio, Alessandra Aprile, Luca Tagliafico, Domenico Soriero, Luca Mastracci, Federica Grillo, Almalina Bacigalupo, Ciro Marrone, Maria Caterina Parodi, Marina Sartini, Maria Luisa Cristina, Roberto Murialdo, Gabriele Zoppoli, Alberto Ballestrero
Summary: This study evaluated the results of laparotomic, laparoscopic, and robotic surgery in treating rectal cancer. The study found that laparoscopic TME is a better choice in a multidisciplinary context, while robotic TME has a significant difference in terms of hospital stay.
Article
Public, Environmental & Occupational Health
B. Casini, A. M. Spagnolo, M. Sartini, B. Tuvo, M. Scarpaci, M. Barchitta, A. Pan, A. Agodi, M. L. Cristina
Summary: This study assessed the effectiveness of duodenoscope reprocessing procedures in Italy and found that 36.81% of duodenoscopes were contaminated, with 22.92% contaminated with high-concern organisms and 13.89% contaminated with low-concern organisms. The contamination rate was highest in samples collected during storage in a non-compliant cabinet and showed a correlation between low-concern organism contamination and storage time.
JOURNAL OF HOSPITAL INFECTION
(2023)
Article
Medicine, General & Internal
Stefano Sartini, Marzia Spadaro, Ombretta Cutuli, Luca Castellani, Marina Sartini, Maria Luisa Cristina, Paolo Canepa, Chiara Tognoni, Agnese Lo, Lorenzo Canata, Martina Rosso, Eleonora Arboscello
Summary: This study aimed to investigate the impact of antithrombotic therapy on adverse outcomes in major trauma patients. The results showed that patients on anticoagulant treatment had higher mortality rates compared to those without antithrombotic treatment and those on antiplatelet treatment, but they also had fewer active treatments.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Infectious Diseases
Giammarco Baiardi, Michela Cameran Caviglia, Fabio Piras, Fabio Sacco, Roberta Prinapori, Maria Luisa Cristina, Francesca Mattioli, Marina Sartini, Emanuele Pontali
Summary: Oritavancin (ORI) is a medication used for the treatment of acute bacterial skin and skin structure infections. Multidose ORI regimens may have potential benefits in treating other Gram-positive infections and have a good safety profile. Further research is needed to determine the optimal multidose ORI scheme.
Article
Infectious Diseases
Andrea Parisini, Silvia Boni, Elisabetta Blasi Vacca, Nicoletta Bobbio, Filippo Del Puente, Marcello Feasi, Roberta Prinapori, Marco Lattuada, Marina Sartini, Maria Luisa Cristina, David Usiglio, Emanuele Pontali
Summary: The SARS-CoV-2 pandemic has had a significant impact on antibiotic resistance in ICU settings, with a decrease in Gram-negative microorganisms and an increase in Gram-positive microorganisms. Both Gram-positive and Gram-negative bacteria showed an increasing trend in antibiotic resistance, possibly due to antibiotic overtreatment and a decrease in containment measures. Carbapenem-resistant K. pneumoniae and P. aeruginosa demonstrated a cumulative lowering trend in resistance.
Review
Microbiology
Maria Luisa Cristina, Anna Maria Spagnolo, Marina Sartini, Alessio Carbone, Martino Oliva, Elisa Schinca, Silvia Boni, Emanuele Pontali
Summary: Candida auris is a major concern in critical care medicine due to its increasing prevalence among immunocompromised patients. This pathogen is difficult to treat and can persist in healthcare environments, leading to prolonged outbreaks.
Article
Geriatrics & Gerontology
P. L. Balzaretti, A. Reano, S. Canonico, M. L. Aurucci, A. Ricotti, F. G. Pili, F. Monacelli, D. Vallino
Summary: Referring older patients to a dedicated geriatric reevaluation clinic after discharge from the emergency department (ED) is associated with fewer early unplanned returns.
EUROPEAN GERIATRIC MEDICINE
(2023)
Review
Health Care Sciences & Services
Marina Sartini, Alessio Carbone, Alice Demartini, Luana Giribone, Martino Oliva, Anna Maria Spagnolo, Paolo Cremonesi, Francesco Canale, Maria Luisa Cristina
Summary: Overcrowding in emergency departments is a widespread phenomenon globally, causing significant negative impacts on hospitals. It results in reduced resources, decreased quality of care, and a lack of timely critical services for patients with medical emergencies.
Article
Health Care Sciences & Services
Domenico Soriero, Paola Batistotti, Rafaela Malinaric, Davide Pertile, Andrea Massobrio, Lorenzo Epis, Beatrice Sperotto, Veronica Penza, Leonardo S. Mattos, Marina Sartini, Maria Luisa Cristina, Alessio Nencioni, Stefano Scabini
Summary: This study analyzed the clinical impact of using 3D models in colorectal surgery. The 3D models provided more accurate lesion localization compared to traditional 2D CT scans, allowing surgeons to better plan the procedures.
Article
Public, Environmental & Occupational Health
G. Piatti, M. Sartini, C. Cusato, A. M. Schito
Summary: This study retrospectively analyzed the incidence of Candida auris infections in the intensive care units of an Italian hospital and compared the relationship between cutaneous and intestinal colonization. The results showed that the proportion of skin and intestinal colonization by Candida auris was similar, and intestinal colonization was associated with an increased risk of urinary tract infections.
JOURNAL OF HOSPITAL INFECTION
(2022)
