Article
Biochemistry & Molecular Biology
Mohammad Alqudah, Rima Abdul Razzaq, Mahmoud A. Alfaqih, Othman Al-Shboul, Ahmed Al-Dwairi, Safa Taha
Summary: This study aimed to investigate the signaling pathways involved in oxytocin-induced contractions in gastric smooth muscle, and found that oxytocin directly stimulates its cell surface receptor to activate PLC beta 1, which in turn liberates IP3, leading to an elevation in intracellular calcium and smooth muscle contraction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Multidisciplinary Sciences
Pablo Castro-Cordova, Maria Jose Mendoza-Leon, Daniel Paredes-Sabja
Summary: In elderly mice, the internalization of Clostridioides difficile spores in the ileum and colonic mucosa is higher compared to adults or young mice, while spore adherence to the ileum and colonic mucosa decreases with aging.
Article
Veterinary Sciences
Jennifer L. MacNicol, Wendy Pearson
Summary: In this study, in vitro organ culture was used to investigate the impact of culturing time and acidic gastric fluid on cultured gastric tissue, as well as the effects of a dietary supplement on biomarkers related to gastric motility and mucosal activity. The results showed that while carbachol and gastric digest did not affect cell viability, they had significant effects on gastrin and nitric oxide secretion. Further research is needed to evaluate the specific effects of the dietary supplement on mucosal activity markers and their relevance in vivo.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Biochemistry & Molecular Biology
K. A. Sharlo, I. D. Lvova, D. A. Sidorenko, S. A. Tyganov, D. T. Sharlo, B. S. Shenkman
Summary: The accumulation of high-energy phosphates plays a crucial role in the shift of muscle fiber type and muscle fatigue during hindlimb suspension in rats, but this area of research is still poorly understood.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
(2023)
Article
Biotechnology & Applied Microbiology
Dong-Sung Won, Yubeen Park, Chu Hui Zeng, Dae Sung Ryu, Ji Won Kim, Jeon Min Kang, Song Hee Kim, Hyung-Sik Kim, Sang Soo Lee, Jung-Hoon Park
Summary: This study investigated the safety and efficacy of self-expandable metallic stent (SEMS)-mediated radiofrequency ablation (RFA) in treating stent-induced tissue hyperplasia in a rat gastric outlet obstruction model. The results showed that repeated or periodic RFA was more effective in treating in-stent restenosis.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2023)
Article
Environmental Sciences
Raina Ardasheva, Natalia Prissadova, Valentin Turiyski, Anna Tolekova, Athanas Krastev, Mina Pencheva, Veselin Popov
Summary: Accelerated electron radiation can affect the signal transduction of 5-HT2A and 5-HT2B receptors in gastric smooth muscle cells, leading to increased receptor expression and altered contractile reactions to exogenous serotonin.
Article
Endocrinology & Metabolism
Shaobo Li, Haoyong Yu, Pin Zhang, Yinfang Tu, Yunfeng Xiao, Di Yang, Yuqian Bao, Junfeng Han, Weiping Jia
Summary: The study found a non-linear relationship between muscle mass and BMI, with psoas muscle mass and eFFMI being better predictors of diabetes remission after Roux-en-Y gastric bypass surgery compared to BMI.
Article
Endocrinology & Metabolism
Shaobo Li, Haoyong Yu, Pin Zhang, Yinfang Tu, Yunfeng Xiao, Di Yang, Yuqian Bao, Junfeng Han, Weiping Jia
Summary: This study found a nonlinear relationship between muscle mass and BMI, and suggested that baseline muscle mass and eFFMI are more reliable predictors of diabetes remission than BMI.
Article
Cell & Tissue Engineering
Keiichiro Uehara, Michiyo Koyanagi-Aoi, Takahiro Koide, Tomoo Itoh, Takashi Aoi
Summary: This study reports the generation of gastric organoids with gastric marker-expressing epithelium from human pluripotent stem cells. It was found that epithelium development occurs prior to muscularis mucosa formation, and Sonic hedgehog (SHH) and TGF-fl1 play a role in this process. Inhibition of HH and TGF-fl signaling prevents subepithelial muscularis mucosa formation. Mechanical properties of the substrate and TGF-fl signaling were shown to influence the emergence of muscularis mucosa in human stomach tissue.
Article
Biology
Nihal A. Ibrahim, Kadreya E. Elmorshedy, Doaa A. Radwan, Manal A. Buabeid
Summary: This study investigated the effects of ciprofloxacin on gastric cell lines in rats, with a focus on physiological, histopathological, and bacteriological changes. The results showed that prolonged oral administration of ciprofloxacin altered the gastric mucosal architecture and bacteriology in albino rats. The treated rats exhibited significantly positive tumor necrosis factor and a significant reduction in serum levels of H. pylori antibodies.
SAUDI JOURNAL OF BIOLOGICAL SCIENCES
(2022)
Article
Gastroenterology & Hepatology
Rita Matos, Hugo Santos Sousa, Jorge Nogueiro, Ana Magalhaes, Celso A. Reis, Fatima Carneiro, Irina Amorim, Freddy Haesebrouck, Fatima Gartner
Summary: The study shows that gastric non-Helicobacter pylori Helicobacter can bind to the human gastric mucosa, with a prevalence of chronic gastritis and chronic active gastritis among patients. Interestingly, these bacteria were found to bind to the gastric mucosa of individuals with severe chronic inflammation and intestinal metaplasia.
Review
Gastroenterology & Hepatology
Fabian Fellipe Bueno Lemos, Marcel Silva Luz, Samuel Luca Rocha Pinheiro, Kadima Nayara Teixeira, Fabricio Freire de Melo
Summary: Gastric mucosa-associated lymphoid tissue lymphoma (GML) is a low-grade B-cell neoplasia commonly associated with chronic gastritis induced by Helicobacter pylori (H. pylori) infection. However, a subset of GML patients are H. pylori-negative. Despite previous beliefs, it has been found that a considerable proportion of H. pylori-negative GML patients show complete remission after bacterial eradication therapy. The mechanisms underlying this treatment responsiveness are not fully understood, and further research is needed to establish the causal relationship between non-H. pylori gastric helicobacters (NHPHs) and GML.
WORLD JOURNAL OF GASTROENTEROLOGY
(2023)
Review
Oncology
Laurent Quero, Mouna Labidi, Marc Bollet, Come Bommier, Sophie Guillerm, Christophe Hennequin, Catherine Thieblemont
Summary: Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is often linked to Helicobacter pylori (H. pylori) infection, with treatment typically consisting of eradicating H. pylori or using radiotherapy. Patients with resistance factors or lack of response to antibiotic therapy may benefit from definitive radiotherapy (RT) as a treatment option.
WORLD JOURNAL OF GASTROINTESTINAL ONCOLOGY
(2021)
Article
Medicine, General & Internal
Jian Han, Jun Wang, Hua-ping Xie
Summary: For gastric MALT lymphoma, endoscopic forceps biopsy may lead to false negative results, highlighting the importance of jumbo biopsy using ESD for accurate diagnosis.
FRONTIERS IN MEDICINE
(2021)
Article
Veterinary Sciences
Roxana Merca, Barbara Richter
Summary: This study presents a rare case of severe anemia caused by heterotopic gastric mucosa in the jejunum of an adult dog. The dog required acute blood transfusion and underwent surgical resection to treat the condition. This report highlights the importance of considering heterotopic gastric mucosa as a differential diagnosis in cases of severe anemia and suspected intestinal tumors.
BMC VETERINARY RESEARCH
(2022)