Review
Medicine, General & Internal
Dong Ah Shin, Min Cheol Chang
Summary: The thermal grill illusion is a paradoxical perception of burning heat and pain caused by simultaneous warm and cold stimuli on the skin. It is generated by supraspinal interactions and the intensity can be affected by factors such as chronic pain, genetic factors, and sexual differences.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
Ellen Lund Schaldemose, Line Raaschou-Nielsen, Rebecca Astrid Bohme, Nanna Brix Finnerup, Francesca Fardo
Summary: Paradoxical heat sensation (PHS) and the thermal grill illusion (TGI) are related to the perception of warmth or heat from innocuous cold stimuli. PHS is common in neuropathy and related to sensory loss, while TGI is more common in healthy individuals. A study of healthy participants found no overlap between PHS and TGI, suggesting that they are distinct phenomena. TGI is associated with normal thermal sensitivity, indicating that efficient thermal sensory function is important for generating the illusory sensation of pain.
NEUROSCIENCE LETTERS
(2023)
Article
Clinical Neurology
Hyung Cheol Kim, Min Cheol Chang, Sung Han Oh, Su Bin Lee, Soo Young Yang, Dong Ah Shin
Summary: This study aimed to evaluate the perception of thermal grill illusion (TGI)-related sensations or pain in patients with chronic lower back pain (CLBP). The CLBP group showed a less intense perception of TGI for sensations of warmth/heat, unpleasantness, and pain than the control group. These results may be useful for clinicians to evaluate the effectiveness of drugs or interventions to manage centralized LBP.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Chemistry, Analytical
Satoshi Saga, Ryotaro Kimoto, Kaede Kaguchi
Summary: The thermal grill illusion can induce a pain sensation under a spatial display of warmth and coolness at around 40 degrees Celsius and 20 degrees Celsius. In order to achieve a more universal virtual pain display during virtual reality experiences, a spatiotemporal control method was proposed to create a variable thermal grill illusion and its effectiveness was evaluated. The study examined the effects of spatial temperature distribution and grid size on the illusion, finding that increasing the temperature difference between warming and cooling shortened the time until pain occurred, and larger thermal areas resulted in larger pain areas and greater magnitude of pain sensation.
Article
Anesthesiology
Frederic Adam, Pauline Jouet, Jean-Marc Sabate, Serge Perrot, Claire Franchisseur, Nadine Attal, Didier Bouhassira
Summary: The thermal grill illusion of pain (TGIP) is a paradoxical burning pain sensation caused by the simultaneous application of warm and cold stimuli on the skin. This study aimed to investigate TGIP in patients with fibromyalgia or irritable bowel syndrome, and found that TGIP responses were significantly greater in these patients compared to controls. The intensity of TGIP was also positively correlated with clinical pain intensity and the cold pain threshold. These findings suggest that TGIP may serve as a clinical marker of central sensitization in patients with chronic pain syndromes.
Article
Neurosciences
Shinji Uragami, Michihiro Osumi
Summary: This study recorded EEG activity during the experience of thermal grill illusion (TGI) and found that theta and alpha bands in the insular cortex and parietal operculum clusters were significantly more desynchronized under the TGI condition compared to the warm condition. Furthermore, theta, alpha, and beta bands in the frontal cluster showed significant desynchronization under the TGI condition. These EEG oscillations in specific brain areas may serve as useful markers of central neuropathic pain.
Article
Biology
Erica O'Neill, Hannah E. Davis, Heath A. MacMillan
Summary: The study found that although the relationship between basal tolerance and plasticity was not significant in non-acclimated flies, there was still a strong correlation between the two in cold-acclimated flies, which may be influenced by statistical artifact. This suggests that previous patterns of thermal tolerance trade-off in similar studies may be affected by regression to the mean effects. Control and correction for such effects are crucial in determining the existence of a trade-off or physiological constraint.
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
(2021)
Article
Engineering, Multidisciplinary
Yunfeng Ma, Linsheng Xu, Ximei Shi
Summary: In order to understand the thermal insulation effect of the tunnel thermal insulation layer under different factors in cold areas, the ABAQUS software was used to simulate the temperature change of the lining in the Jiangluling Tunnel. The thermal insulation effect was analyzed under different insulation layer laying methods, insulation material heat conductivity coefficients, insulation layer thickness values, and air temperature conditions. The research results showed that the thermal insulation performance was highest for the wall-attaching style insulation layer and the thickness should be at least 5.5 cm. The thermal insulation material should have a thermal conductivity coefficient between 0.025 and 0.04 (W/m.k) and be laid throughout the entire tunnel. Extra thermal insulation measures should be taken when the temperature drops below -17 degrees C to ensure the frost resistance and prevention ability of the tunnel structure.
ALEXANDRIA ENGINEERING JOURNAL
(2023)
Article
Neurosciences
Yuka Oono, Hidenori Kubo, Saori Takagi, Kelun Wang, Lars Arendt-Nielsen, Hikaru Kohase
Summary: The study found that simultaneous exposure to painful cold-heat stimuli can induce paradoxical sensations, especially through ipsilateral integration. Paradoxical sensations have diagnostic value, and quantifying them using a simple bedside tool may be useful in the clinical setting.
SOMATOSENSORY AND MOTOR RESEARCH
(2022)
Article
Environmental Sciences
Clemens Schwingshackl, Jana Sillmann, Ana Maria Vicedo-Cabrera, Marit Sandstad, Kristin Aunan
Summary: This study calculated trends of heat stress indicators in different climate models under global warming, finding significant increases in all regions globally. The research indicates that different heat stress indicators show substantial variations in exceeding impact-relevant thresholds, highlighting the importance of selecting appropriate indicators and thresholds for reliable assessments.
Article
Construction & Building Technology
Wenjie Ji, Richard de Dear, Jungsoo Kim, Yingxin Zhu, Bin Cao, Shuli Liu
Summary: The study found that the thermal preference of Chinese female migrants in Australia was influenced by their recent climatic exposure, and it takes about 1 week to adapt from a cold climate to a hot climate.
BUILDING AND ENVIRONMENT
(2022)
Article
Plant Sciences
Sang-Min Park, Su-Jin Baek, Hyo-Jeong Ban, Hee-Jeong Jin, Seongwon Cha
Summary: Effective treatments for temperature-related symptoms are limited, and the molecular mechanisms of the hot and cold effects of traditional herbal medicines are not fully understood. This study aimed to systematically elucidate the molecular mechanisms of herbal medicines' hot and cold properties through an unbiased large-scale investigation of herbal ingredients, target genes, and induced transcriptome signatures. The results provide novel connections between herbal ingredients, target genes, and pathways, which may contribute to the development of pharmacological treatment strategies for temperature-related pain using medicinal plants.
Article
Clinical Neurology
Jan Petter Neverdahl, Martin Uglem, Dagfinn Matre, Johannes Orvin Hansen, Morten Engstrom, Erling Tronvik, Lars Jacob Stovner, Trond Sand, Petter Moe Omland
Summary: This study did not provide strong evidence for an increased effect of sleep restriction on pain sensitivity in migraineurs compared to healthy controls, but there might be a slightly increased effect in certain migraine subgroups.
Article
Chemistry, Multidisciplinary
Gabriel Chiriac, Dumitru Dorin Lucache, Costica Nituca, Alin Dragomir, Seeram Ramakrishna
Summary: The use of electric buses is on the rise globally to reduce pollution in urban areas. Heating is the biggest energy consumption in electric buses, and accurate estimation of heat loss and heating energy is crucial.
APPLIED SCIENCES-BASEL
(2021)
Article
Medicine, General & Internal
Bjorn Gerdle, Karin Wahlen, Torsten Gordh, Bijar Ghafouri
Summary: Chronic widespread pain, including fibromyalgia, is characterized by generalized musculoskeletal pain and increased pain sensitivity. A study found differences in correlation patterns between plasma/muscle proteins and thermal pain thresholds in patients compared to healthy controls, with immune system proteins playing important roles in pain thresholds.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Rheumatology
Elisabeth Jochmann, Michael Karl Boettger, Praveen Anand, Hans-Georg Schaible
ARTHRITIS RESEARCH & THERAPY
(2015)
Article
Rheumatology
Matthias Ebbinghaus, Mieczyslaw Gajda, Michael K. Boettger, Hans-Georg Schaible, Rolf Braeuer
ANNALS OF THE RHEUMATIC DISEASES
(2012)
Article
Clinical Neurology
Nils Gebhardt, Karl-Juergen Baer, Michael K. Boettger, Gisela Grecksch, Gerburg Keilhoff, Rupert Reichart, Axel Becker
Article
Radiology, Nuclear Medicine & Medical Imaging
Frederic Dietzel, Michael Karl Boettger, Katja Dahlke, Jana Hoelzer, Frank Lehmann, Mieczyslaw Gajda, Rolf Braeuer, Hans-Georg Schaible, Werner Alois Kaiser, Ingrid Hilger
INVESTIGATIVE RADIOLOGY
(2013)
Article
Pharmacology & Pharmacy
Karl-Juergen Baer, Janneke Terhaar, Michael Karl Boettger, Silke Boettger, Sandy Berger, Thomas Weiss
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY
(2011)
Article
Neurosciences
Gisela Segond von Banchet, Michael K. Boettger, Christian Koenig, Yoichiro Iwakura, Rolf Braeuer, Hans-Georg Schaible
MOLECULAR AND CELLULAR NEUROSCIENCE
(2013)
Article
Anesthesiology
Thomas Hilberg, Doerte Czepa, David Freialdenhoven, Michael Karl Boettger
Article
Anesthesiology
Michael Karl Boettger, Christiane Schwier, Karl-Juergen Baer
Article
Multidisciplinary Sciences
Johannes Leuchtweis, Michael K. Boettger, Fanny Niv, Christoph Redecker, Hans-Georg Schaible
Article
Multidisciplinary Sciences
Gabriel Natura, Karl-Juergen Baer, Annett Eitner, Michael K. Boettger, Frank Richter, Susanne Hensellek, Andrea Ebersberger, Johannes Leuchtweis, Takayuki Maruyama, Gunther Olaf Hofmann, Karl-Juergen Halbhuber, Hans-Georg Schaible
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2013)
Article
Psychiatry
Michael Karl Boettger, David Grossmann, Karl-Juergen Baer
PSYCHOSOMATIC MEDICINE
(2013)
Article
Rheumatology
Michael K. Boettger, Johannes Leuchtweis, Hans-Georg Schaible, Manuela Schmidt
ARTHRITIS RESEARCH & THERAPY
(2011)
Article
Rheumatology
Michael Karl Boettger, Diana Kuemmel, Andrew Harrison, Hans-Georg Schaible
ARTHRITIS RESEARCH & THERAPY
(2011)
Article
Rheumatology
Michael Karl Boettger, Susanne Krucker, Mieczyslaw Gajda, Hans-Georg Schaible, Thomas Hilberg
ARTHRITIS RESEARCH & THERAPY
(2013)