Journal
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
Volume 13, Issue 3, Pages 286-289Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.ejpn.2008.05.004
Keywords
Vagus nerve stimulation; Non-convulsive status epilepticus; Refractory status epilepticus; Children
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Funding
- Fund for Scientific Research-Flanders (FWO)
- Ghent University Research Fund [B/05875]
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We report on the long-term follow-up of a patient with refractory non-convulsive SE who was successfully treated with VNS. A 7-year old girl with a medical history of thrombosis in the right internal cerebral vein and right thalamic bleeding 8 days after birth, developed epilepsy at the age of 13 months. At the age of 6 she presented with a refractory non-convulsive SE. A vagus nerve stimulator was placed after 11 days of thiopental-induced coma. Three days after VNS implantation, the thiopental-induced coma was successfully withdrawn and electroencephalography showed normalization one week after start of VNS. After a follow-up of 13 months she remains seizure-free and AEDs have been partially tapered. This case illustrates a potential acute abortive effect with sustained long-term seizure reduction of VNS in a 7-year old girl who presented with refractory non-convulsive SE. (C) 2008 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.
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