Article
Orthopedics
Omer Sofulu, Evrim Sirin, Fevzi Saglam, Abbas Tokyay, Servet Igrek, Bulent Erol
Summary: EPR showed to provide durable fixation with high implant survival rate and good clinical and functional outcomes for patients with extensive proximal femoral metastases associated with pathological fractures. Complications resulting in reconstruction failure were relatively low, with particular attention needed to Trendelenburg gait.
Article
Oncology
Vincent Crenn, Yonis Quinette, Charlie Bouthors, Gilles Missenard, Brice Viard, Philippe Anract, Stephane Boisgard, Eric Mascard, Francois Gouin
Summary: The study suggests that using a vascularised fibula graft (VFG) in femoral reconstructions can promote bone union and reduce mid- to long-term revision risks. However, irradiated allografts increase the risk of revisions. Therefore, in cases of tumors, it is recommended to choose VFG+ from fresh-frozen allografts.
WORLD JOURNAL OF SURGICAL ONCOLOGY
(2022)
Article
Orthopedics
Joshua D. Johnson, Robert L. Satcher, Lei Feng, Valerae O. Lewis, Bryan S. Moon, Justin E. Bird, Patrick P. Lin
Summary: In this study, the survivorship and risk of revision for patients undergoing cemented intercalary endoprosthetic replacement for diaphyseal metastasis were evaluated. The study found that the procedure provided stability and short-term improvement in function for patients, although aseptic loosening was a concern, particularly in the humerus.
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH
(2023)
Article
Oncology
Michal Mahdal, Lukas Pazourek, Vasileios Apostolopoulos, Dagmar Adamkova Krakorova, Iva Staniczkova Zambo, Tomas Tomas
Summary: This study evaluated the implant survival, functional score, and complications of intercalary endoprostheses in patients with metastatic involvement of the femoral and humeral diaphysis. The findings showed that resection of bone metastases and replacement with intercalary endoprosthesis had excellent immediate functional results with an acceptable level of complications in prognostically favourable patients.
Article
Orthopedics
Venkat Boddapati, Michael B. Held, Matthew Levitsky, Ryan S. Charette, Alexander L. Neuwirth, Jeffrey A. Geller
Summary: The study found that patients undergoing hip arthroplasty for pathologic proximal femur fractures have higher rates of complications and mortality compared to osteoarthritis patients, and longer operative durations. However, patients with a pathological fracture have similar rates of morbidity and mortality as nonpathological fracture patients, but require more perioperative blood transfusions and unplanned readmissions.
JOURNAL OF ARTHROPLASTY
(2021)
Article
Critical Care Medicine
Alessandro Cappellari, Giulia Trovarelli, Alberto Crimi, Elisa Pala, Andrea Angelini, Antonio Berizzi, Pietro Ruggieri
Summary: Long bone metastases are a disease of high social importance. This study aimed to evaluate surgically treated patients with bone metastases and compare the outcomes of solitary metastasis, oligometastases, and multiple metastases. The results showed that patients with solitary metastasis or oligometastases had significantly better overall survival than those with multiple metastases. Patients treated with resection and prosthesis had better survival than those treated with nailing.
INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED
(2023)
Article
Oncology
Joshua R. Labott, Mark J. Heidenreich, Samuel E. Broida, Gavin L. Mills, Peter S. Rose, Matthew T. Houdek
Summary: Reconstruction of the humeral diaphysis with an intercalary endoprosthesis restores upper extremity function, but one in four patients may experience mechanical failure.
JOURNAL OF SURGICAL ONCOLOGY
(2023)
Article
Computer Science, Interdisciplinary Applications
Ziyang He, Siyi Huang, Tao Ji, Xiaodong Tang, Rongli Yang, Wei Guo
Summary: The relationship between plate configuration and initial stability for femoral intercalary reconstruction using allo-/autograft was explored in this study. Finite element simulations showed that the configurations of lateral bridging plate + medial adjuvant plate (LP + MAP) and lateral bridging plate + medial bridging plate (LP + MP) exhibited superior stability in terms of axial compression and torsion load.
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
(2022)
Article
Orthopedics
Elisa Pala, Alberto Procura, Giulia Trovarelli, Antonio Berizzi, Pietro Ruggieri
Summary: This study compared titanium and carbon fiber intramedullary nails in terms of response to radiotherapy, disease control, surgery time, fluoroscopy exposure, and complications. The results suggested that carbon fiber nails had shorter surgical time and faster healing.
EFORT OPEN REVIEWS
(2022)
Article
Surgery
David S. Margolis, Gerardo Figueroa, Efren Barron Villalobos, Jordan L. Smith, Cynthia J. Doane, David A. Gonzales, John A. Szivek
Summary: This article details the surgical technique for creating a 42 mm mid-diaphyseal femoral defect stabilization with an intramedullary device in sheep, along with additional surgical details for dynamization, reverse dynamization, and device removal. It also compares the use of each stabilization technique in clinically significant large critical-size bone defects.
JOURNAL OF INVESTIGATIVE SURGERY
(2022)
Article
Orthopedics
Chang-Wug Oh, Joon-Woo Kim, Kyeong-Hyeon Park, Jong-Keon Oh, Yong-Cheol Yoon, Seung-Ho Chung
Summary: Comparison between reconstruction and standard nailing for diaphyseal AFFs showed that reconstruction nailing can achieve satisfactory outcomes and reduce the risk of delayed peri-implant fragility fractures, newly developed subtrochanteric AFFs, and nonunion.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2022)
Article
Orthopedics
Feifei Pu, Zhicai Zhang, Baichuan Wang, Jianxiang Liu, Zengwu Shao
Summary: En bloc resection and intercalary prosthesis implantation for humeral diaphyseal bone metastases can significantly reduce pain, improve limb function, extend survival time, and enhance quality of life for patients.
INTERNATIONAL ORTHOPAEDICS
(2021)
Article
Orthopedics
Xianhao Shao, Mengmeng Dou, Qiang Yang, Jianmin Li, Ailin Zhang, Yuan Yao, Qing Chu, Ka Li, Zhenfeng Li
Summary: Two novel 3D-printed customized intercalary femoral prostheses were used to reconstruct massive bone defects in oncologic patients, achieving satisfactory postoperative outcomes and increasing the opportunities for joint-preserving tumor resection.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Article
Multidisciplinary Sciences
Pietro Feltri, Luca Solaro, Alessandro Di Martino, Christian Candrian, Costantino Errani, Giuseppe Filardo
Summary: This study reviewed and summarized the surgical techniques used to treat large, long-bone diaphyseal defects, comparing the pros and cons of each technique. The results showed differences in terms of primary union, complications, reinterventions, and failure rates among different technique groups.
SCIENTIFIC REPORTS
(2022)
Article
Oncology
Floortje G. M. Verspoor, Gerjon Hannink, Michael Parry, Lee Jeys, Jonathan D. Stevenson
Summary: This study aimed to describe the diagnostic accuracy, morbidity, and sarcoma incidence of biopsy results in patients with pathological proximal femoral fractures. The study found that biopsy can differentiate between sarcoma and non-sarcoma, but it delays surgery time, results can be inconclusive or false, and it increases the risk of fractures.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Article
Medicine, Research & Experimental
Hironari Tamiya, Hyungsoo Kim, Oleksiy Klymenko, Heejung Kim, Yongmei Feng, Tongwu Zhang, Ji Yun Han, Ayako Murao, Scott J. Snipas, Lucia Jilaveanu, Kevin Brown, Harriet Kluger, Hao Zhang, Kazuhiro Iwai, Ze'ev A. Ronai
JOURNAL OF CLINICAL INVESTIGATION
(2018)
Article
Oncology
Takaaki Nakai, Yoshinori Imura, Hironari Tamiya, Shutaro Yamada, Sho Nakai, Naohiro Yasuda, Keiko Kaneko, Hidetatsu Outani, Satoshi Takenaka, Kenichiro Hamada, Akira Myoui, Nobuhito Araki, Takafumi Ueda, Kazuyuki Itoh, Hideki Yoshikawa, Norifumi Naka
Article
Oncology
Yuichiro Ukon, Takaaki Tanaka, Shigenori Nagata, Hiroki Hagizawa, Yoshinori Imura, Hironari Tamiya, Kazuya Oshima, Norifumi Naka, Yasuaki Aoki, Shigeyuki Kuratsu
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Kenichiro Hamada, Yasuhiko Tomita, Eiichi Konishi, Tetsuho Fujimoto, Yu Fen Jin, Hidetatsu Outani, Hironari Tamiya, Norifumi Naka, Nobuhito Araki
CLINICAL NUCLEAR MEDICINE
(2009)
Article
Cell Biology
Tsuyoshi Takiuchi, Tomoko Nakagawa, Hironari Tamiya, Hiroaki Fujita, Yoshiteru Sasaki, Yasushi Saeki, Hiroyuki Takeda, Tatsuya Sawasaki, Alexander Buchberger, Tadashi Kimura, Kazuhiro Iwai
Article
Immunology
Hironari Tamiya, Mika Terao, Tsuyoshi Takiuchi, Masaki Nakahara, Yoshiteru Sasaki, Ichiro Katayama, Hideki Yoshikawa, Kazuhiro Iwai
JOURNAL OF IMMUNOLOGY
(2014)
Article
Cell Biology
Hyungsoo Kim, Heejung Kim, Yongmei Feng, Yan Li, Hironari Tamiya, Stefania Tocci, Ze'ev A. Ronai
SCIENCE TRANSLATIONAL MEDICINE
(2020)
Article
Oncology
Hideaki Sabe, Akitomo Inoue, Shigenori Nagata, Yoshinori Imura, Toru Wakamatsu, Satoshi Takenaka, Hironari Tamiya
Summary: Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor that may not necessarily be driven by IL-6, as inhibition of the IL-6 signaling pathway controlled paraneoplastic inflammatory syndrome (PIS) but did not prevent tumor progression.
CASE REPORTS IN ONCOLOGICAL MEDICINE
(2021)
Article
Otorhinolaryngology
Nao Hashida, Hironari Tamiya, Mizuki Korematsu, Takashi Fujii
Summary: This study aimed to investigate the differences between fluid restriction, thickened fluids, and no restriction of fluids in preventing aspiration pneumonia in patients with dysphagia after head and neck cancer treatment. Retrospective analysis of 654 patients showed that fluid restriction did not reduce the risk of aspiration pneumonia.
AURIS NASUS LARYNX
(2023)
