Review
Dentistry, Oral Surgery & Medicine
Wei Guang Bi, Kaiyang Li
Summary: This study compared the effectiveness and side effects of miniscrew-assisted rapid maxillary expansion (MARME) with conventional rapid maxillary expansion (RME) in the treatment of transverse maxillary deficiency. The results showed that MARME achieved greater palatal suture opening, increased palatal width, and reduced buccal inclination compared to traditional RME.
CLINICAL ORAL INVESTIGATIONS
(2022)
Review
Otorhinolaryngology
Christian Calvo-Henriquez, Joaquim Megias-Barrera, Carlos Chiesa-Estomba, Jerome R. Lechien, Byron Maldonado Alvarado, Badr Ibrahim, David Suarez-Quintanilla, Sandra Kahn, Robson Capasso
Summary: This study investigates the potential causes of nasal surgery failures and the impact of maxillary expansion on nasal function. The results indicate that palatal expansion can significantly reduce nasal resistance and improve subjective scores, but further high-quality studies are needed to determine its effectiveness as a primary treatment option for addressing nasal breathing problems.
AMERICAN JOURNAL OF RHINOLOGY & ALLERGY
(2021)
Review
Dentistry, Oral Surgery & Medicine
Angeline Antezack, Romain Ohanessian, Camille Sadowski, Mathias Faure-Brac, Arthur Brincat, Damien Etchecopar-Etchart, Virginie Monnet-Corti
Summary: Surgical root coverage has a significant effect on suppressing dentin hypersensitivity associated with gingival recession.
JOURNAL OF CLINICAL PERIODONTOLOGY
(2022)
Review
Dentistry, Oral Surgery & Medicine
Maria-Zoi Theodoridou, Athanasia-Eirini Zarkadi, Vasileios F. Zymperdikas, Moschos A. Papadopoulos
Summary: This systematic review aimed to assess the long-term effectiveness of non-surgical treatment for open bite patients. The results showed that non-surgical treatment had minimal effects on skeletal tissues and incisor inclination, while only the nasolabial angle was significantly reduced in the long term.
PROGRESS IN ORTHODONTICS
(2023)
Review
Orthopedics
Violet Man-Chi Ko, Mingde Cao, Jihong Qiu, Isaac Chun-Kit Fong, Sai-Chuen Fu, Patrick Shu-Hang Yung, Samuel Ka-Kin Ling
Summary: This systematic review evaluated the clinical effectiveness of various non-surgical treatments for insertional Achilles tendinopathy. The combination of eccentric exercise and soft tissue therapy was found to be the most effective treatment for short-term pain. However, the overall confidence in non-surgical treatments from all included trials was very low, and no recommendation of the best treatment option can be made from this review.
BMC MUSCULOSKELETAL DISORDERS
(2023)
Review
Dentistry, Oral Surgery & Medicine
Wei-Cheng Lee, Yi-Shing Shieh, Yu-Fang Liao, Cho-Hao Lee, Chiung Shing Huang
Summary: This meta-analysis evaluated the long-term three-dimensional skeletal effects of maxillary protraction with or without rapid maxillary expansion in skeletal class III growing patients. The results suggest that these treatments may not be effective in long-term correction of maxillary anteroposterior hypoplasia. Further long-term studies are needed to assess their skeletal benefits on maxilla in vertical and transverse dimensions.
JOURNAL OF DENTAL SCIENCES
(2021)
Review
Pediatrics
Martina Barone, Alberto De Stefani, Filippo Cavallari, Antonio Gracco, Giovanni Bruno
Summary: The aim of this systematic review is to evaluate the pain perceived by patients during rapid maxillary expansion (RME) and its relation to demographic characteristics, appliance type, activation protocol, and the use of medication or pain management strategies. A total of ten studies were included in the review, and pain was found to be a common effect of RME treatment that tends to decrease over time. The design and protocol of the expander used can influence perceived pain. Some pain management strategies can be effective in reducing RME-associated pain.
Review
Chemistry, Multidisciplinary
Laura Mello Figueiredo, Daniella Mascarenhas Calixto Barros, Natalia Costa Veloso, Cinthia Oliveira Lisboa, Carlos Fernando Mourao, Adriana de Alcantara Cury-Saramago, Claudia Trindade Mattos, Jose de Albuquerque Calasans-Maia
Summary: This study evaluated the density of the midpalatal suture in individuals undergoing maxillary expansion using different treatment methods and found variations in the efficacy of rapid maxillary expansion, surgically assisted rapid maxillary expansion, and miniscrew-assisted rapid palatal expansion in different regions.
APPLIED SCIENCES-BASEL
(2023)
Review
Geriatrics & Gerontology
Xuemei Sun, Wenqi Liu, Yinyan Gao, Lang Qin, Hui Feng, Hongzhuan Tan, Qiong Chen, Linlin Peng, Irene X. Y. Wu
Summary: Frailty poses a threat to the health of older adults, and its prevalence continues to rise with global population aging. This study conducted a network meta-analysis to update the evidence on the effectiveness of non-pharmacological interventions for frailty. The results showed that physical activity, multicomponent intervention, and nutrition intervention were associated with reducing frailty, with physical activity being the most effective. Among different types of physical activity, resistance training was found to be the most effective intervention.
Review
Medicine, General & Internal
Chao Xiao, Qingquan Shi, Qijun Cheng, Jianli Xu
Summary: A systematic review and meta-analysis indicated that single-dose MTX is more effective with fewer side effects compared to multiple-dose therapies for tubal EP. It is recommended as the first-line treatment for patients requiring conservative therapy. Expectant treatment is suggested for EP patients with a low-hCG level to reduce adverse effects.
Review
Chemistry, Multidisciplinary
Alessia Pardo, Andrea Butera, Angela Giordano, Simone Gallo, Maurizio Pascadopoli, Andrea Scribante, Massimo Albanese
Summary: The aim of this study was to evaluate the adjunctive effects of photodynamic therapy (aPDT) on nonsurgical mechanical treatment in patients with periodontitis. The results showed that despite the limited number of RCTs and the great heterogeneity between them, it can be concluded that aPDT in association with nonsurgical periodontal treatment improved the clinical parameters at 3 months.
APPLIED SCIENCES-BASEL
(2023)
Review
Cell Biology
Zilong Chen, Zhiming Hong, Shengjie Wang, Junfeng Qiu, Quan Wang, Yangling Zeng, Haowei Weng
Summary: Infertility is a significant global public health problem, affecting about 10% of the world's population. This network meta-analysis investigated the efficacy of non-pharmaceutical interventions on sperm quality. The results suggest that omega-3 fatty acids, lycopene, acupuncture, and vitamin have evident advantages in improving sperm concentration, motility, and forward motility.
Review
Dentistry, Oral Surgery & Medicine
Jonathan Luyten, Noemi M. C. De Roo, Jeroen Christiaens, Leonie Van Overberghe, Liesbeth Temmerman, Guy A. M. De Pauw
Summary: This study compared the dentoalveolar outcomes of slow maxillary expansion (SME) and rapid maxillary expansion (RME) in patients with cleft lip and/or palate (CL/P) before secondary alveolar bone grafting. The results showed that both SME and RME achieved similar posterior expansion, but SME had a greater anterior differential expansion. The effects on dental tipping were inconclusive.
ANGLE ORTHODONTIST
(2023)
Review
Dentistry, Oral Surgery & Medicine
Igor Carvalho Chaves, Dayrine Silveira de Paula, Mario Rogerio Lima Mota, Fabricio Bitu Sousa, Paulo Goberlanio de Barros Silva, Ana Paula Negreiros Nunes Alves
Summary: This article conducted a systematic review to investigate the effect of low-level laser therapy on bone neoformation after transverse maxillary expansion. The results from meta-analysis showed that photobiomodulation as an adjuvant therapy has limited contribution to bone healing in the midpalatal suture region after a period of 3 months.
ORTHODONTICS & CRANIOFACIAL RESEARCH
(2023)
Review
Otorhinolaryngology
C. Calvo-Henriquez, V. Sandoval-Pacheco, C. Chiesa-Estomba, J. R. Lechien, S. Martins-Neves, E. Esteller-More, S. Kahn, D. Suarez-Quintanilla, R. Capasso
Summary: This systematic review and meta-analysis found a positive effect of pediatric maxillary expansion in conductive hearing loss in well-select children. However, results cannot be extrapolated for children with conductive hearing loss without an accompanying orthodontic indication (maxillary constriction). It showed that the existing prospective studies exhibited qualitative pitfalls, limiting the ability to obtain conclusive evidence about the role of pediatric maxillary expansion on conductive hearing loss in children.
EUROPEAN ANNALS OF OTORHINOLARYNGOLOGY-HEAD AND NECK DISEASES
(2023)
Article
Dentistry, Oral Surgery & Medicine
Meiya Gao, Xinyu Yan, Rui Zhao, Yue Shan, Yiyin Chen, Fan Jian, Hu Long, Wenli Lai
Summary: This study compared pain perception, anxiety, and impacts on oral health-related quality of life between adult patients receiving clear aligners and fixed appliances during the initial stage of orthodontic treatments. Patients treated with clear aligners experienced lower pain levels, less anxiety, and higher OHRQoL compared to those receiving fixed appliances.
EUROPEAN JOURNAL OF ORTHODONTICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
H. Liang, H. Hu, D. Shan, J. Lyu, X. Yan, Y. Wang, F. Jian, X. Li, W. Lai, H. Long
Summary: CGRP is upregulated in trigeminal neurons and SGCs following orofacial pain induction. Knockdown of CGRP reduces pain and its expression in neurons and SGCs. CGRP upregulates inducible nitric oxide synthase in SGCs through p38 signaling pathway, leading to a positive-feedback neuron-glia crosstalk mediated by CGRP.
JOURNAL OF DENTAL RESEARCH
(2021)
Review
Dentistry, Oral Surgery & Medicine
Lu Liu, Qi Zhan, Jing Zhou, Qianyun Kuang, Xinyu Yan, Xiaoqi Zhang, Yue Shan, Wenli Lai, Hu Long
Summary: This study compared the effects of Forsus appliances with and without temporary anchorage devices (TADs) for patients with skeletal Class II malocclusion. The results showed that TADs, especially miniplates, were able to eliminate the dental adverse effects of Forsus appliances for the correction of skeletal Class II malocclusion.
ANGLE ORTHODONTIST
(2021)
Article
Clinical Neurology
Rui Guo, Yiyin Chen, Lu Liu, Jing Wen, Hong Yang, Yafen Zhu, Meiya Gao, Hengyan Liang, Wenli Lai, Hu Long
Summary: NGF plays an important role in regulating orofacial pain by positively regulating CCL19 expression in the trigeminal ganglia of rats, while CCL19 increases sensitivity to experimental tooth movement orofacial pain.
FRONTIERS IN NEUROLOGY
(2021)
Article
Medicine, General & Internal
Xinyu Yan, Xiaoqi Zhang, Yiyin Chen, Hu Long, Wenli Lai
Summary: This study aimed to evaluate the association between upper lip characteristics (ULCs) and skeletal patterns (SPs) in 2079 patients. Results showed significant variations in ULCs among different SPs, with superior sulcus depth being independently associated with SPs. Adjustment for confounders revealed superior sulcus depth as the only ULC significantly corrected by intervention of skeletal growth.
Article
Dentistry, Oral Surgery & Medicine
Di Shan, Yuwei He, Meiya Gao, He Liu, Yafen Zhu, Lina Liao, Farnaz Hadaegh, Hu Long, Wenli Lai
Summary: The study found that resin infiltration and microabrasion are similarly effective in reducing the sizes of white spot lesions, but resin infiltration has an esthetic advantage over microabrasion.
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
(2021)
Article
Dentistry, Oral Surgery & Medicine
Lu Liu, Qinxuan Song, Jing Zhou, Qianyun Kuang, Xinyu Yan, Xiaoqi Zhang, Yue Shan, Xiaolong Li, Hu Long, Wenli Lai
Summary: This study analyzed the effects of aligner overtreatment on torque control and incisor intrusion during anterior retraction. The results showed that clear aligner therapy caused lingual tipping, extrusion, and intrusion of teeth. Canine attachments enhanced these effects and required more support from posterior teeth. Appropriate overtreatment with attachments can achieve incisor intrusion and palatal root torquing.
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
(2022)
Article
Cell Biology
Qingxuan Wang, Jing Xie, Chenchen Zhou, Wenli Lai
Summary: The stiffness of the substrate plays a crucial role in osteoclast differentiation and function, with higher stiffness accelerating osteoclast formation and activity. Higher stiffness substrates can also activate cytoskeletal adhesion molecules and biochemical signaling cascades.
CELL PROLIFERATION
(2022)
Review
Dentistry, Oral Surgery & Medicine
Ziwei Tang, Jiawei Zhou, Hu Long, Yanzi Gao, Qingxuan Wang, Xiaolong Li, Yan Wang, Wenli Lai, Fan Jian
Summary: This article aims to explore the mechanisms and treatments of orthodontic pain, with the hope of providing insights for future pain relief in orthodontic treatment.
JOURNAL OF ORAL REHABILITATION
(2022)
Article
Medicine, General & Internal
Shizhen Zhang, Xiaoyu Wei, Lufei Wang, Zhouqiang Wu, Lu Liu, Xinyu Yan, Wenli Lai, Hu Long
Summary: This study evaluated the bone thickness and determined the optimal sites for orthodontic mini implant insertion in the mandibular symphysis. The results showed that the bone thickness was influenced by facial types and insertion locations, heights, and angles.
Article
Medicine, General & Internal
Jing Zhou, Hong Zhou, Lingling Pu, Yanzi Gao, Ziwei Tang, Yi Yang, Meng You, Zheng Yang, Wenli Lai, Hu Long
Summary: The study aimed to develop an AI system for automatically determining CVM status, and found that the AI system showed good agreement with human examiners in terms of labelling error. Additionally, the AI system demonstrated good accuracy in CVM staging and achieved high F1 scores, indicating its reliability and usefulness in evaluating cervical vertebral maturation.
Article
Neurosciences
Feifei Zhang, Fei Li, Hong Yang, Yu Jin, Wenli Lai, Graham J. Kemp, Zhiyun Jia, Qiyong Gong
Summary: This study found that brain functional networks retain small-world organization during orthodontic pain stimulation. The nodal centrality of ipsilateral brain nodes to the pain stimulus was enhanced, while the centrality of contralateral brain areas was decreased. Furthermore, anxiety mediated the relationship between nodal efficiency of the mid-cingulate cortex and pain severity.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Lingling Pu, Jing Zhou, Xinyu Yan, Hong Zhou, Xian Liu, Zheng Yang, Chengge Hua, Liang Zhang, Wenli Lai, Hu Long
Summary: The orthodontic technique using a miniscrew-anchored cantilever spring proved to be effective in substituting deeply impacted third molars for second molars with severe root resorption, achieving successful treatment outcomes that satisfied the patient.
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2022)
Article
Dentistry, Oral Surgery & Medicine
Zhouqiang Wu, Xiaolei Gao, Hu Long, Wenli Lai
Summary: This study quantified facial asymmetry using 3D technology and compared it with evaluations by non-experts. The results showed that the chin and lateral mandible areas significantly contribute to facial symmetry, confirming the reliability of 3D technology in objectively measuring facial symmetry.
Article
Computer Science, Artificial Intelligence
Ke Zou, Tianjin Tao, Xuedong Yuan, Xiaojing Shen, Wenli Lai, Hu Long
Summary: In this study, an Interactive Dual-Branch Network (IDBNet) is proposed for automatic and accurate segmentation of the hard palate in the oral cavity. The IDBNet utilizes a dual-branch encoder-decoder, a channel map interaction module, and a guide map interaction module to effectively handle the diversity of hard palate shapes and intensity variations in different regions. Experimental results on an in-house dataset demonstrate the superior performance of the IDBNet method for hard palate segmentation.
APPLIED SOFT COMPUTING
(2022)