Article
Engineering, Biomedical
Joana Fontes, Victor Zacharias Martin, Marta Resende, Bruno Colaco, Pedro de Sousa Gomes, Jose Manuel Amarante
Summary: This study investigated the stability of orthodontic mini-implants under immediate orthodontic functional load, with or without splinting, and examined the histomorphometric parameters of the adjacent bone tissue in an in vivo experimental model. Mini-implants were placed in rabbits' proximal tibia and loaded with a 150g force. The study found that splinting reduced the tipping of mini-implants to levels similar to unloaded implants, and immediate loading increased bone formation at the peri-implant region. This study highlights the importance of splinting in minimizing displacement while promoting bone formation in orthodontic treatment with mini-implants.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Cell Biology
Stephan Frosch, Gottfried Buchhorn, Sebastian Krohn, Wolfgang Lehmann, Karl-Heinz Frosch, Laszlo Fuezesi, Alice Frosch
Summary: This study compared the histomorphometric effect of Ti-6Al-4V implants with different porous structures on osseointegration in animals, showing that porous implants can promote more new bone formation and enhance bone-implant contact.
HISTOLOGY AND HISTOPATHOLOGY
(2021)
Article
Multidisciplinary Sciences
Jeong-Min Hong, Ung-Gyu Kim, In-Sung Luke Yeo
Summary: Histological analysis is the gold standard for evaluating osseointegration, but it is invasive and represents only one plane. Micro-computed tomography (mu CT) offers three-dimensional information but has resolution and artifact issues, making it a supplementary method. This study compared histomorphometric BIC ratios with mu CT BIC ratios and found correlations between 2D-mu CT and histomorphometric methods.
Article
Multidisciplinary Sciences
Kristian Kniha, Benita Hermanns-Sachweh, Faruk Al-Sibai, Reinhold Kneer, Stephan Christian Moehlhenrich, Marius Heitzer, Frank Hoelzle, Ali Modabber
Summary: The purpose of this rat study was to investigate the feasibility of temperature thresholds affecting bone contact at the surface of implants in vivo. The results showed that thermal necrosis should be used for implant removal in subsequent in vivo studies. The study found that temperatures ranging from 48°C to 50°C led to a decrease in the BIC ratio, with significant differences observed between the 50°C group and the control group. However, there were no significant variations within the cold temperatures.
SCIENTIFIC REPORTS
(2022)
Article
Medicine, General & Internal
Marco Montevecchi, Gianluca Marucci, Barbara Pignataro, Gabriela Piana, Giulio Alessandri-Bonetti, Vittorio Checchi
Summary: During orthodontic extrusion, histomorphometric analysis suggests that a decrease in osteoblastic/osteoclastic cell activity is a sign of bone formation and maturation. The maturation of alveolar bone requires a period of 2 months stabilization.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Pier Gallo, David Diaz-Baez, Sandra Perdomo, Antonio Carlos Aloise, Mustafa Tattan, Muhammad H. A. Saleh, Andre Antonio Pelegrine, Andrea Ravida, Hom-Lay Wang
Summary: This study aimed to assess vital mineralized tissue formation in vertical ridge augmentation procedures using autogenous bone chips mixed with either an allograft or a xenograft.
CLINICAL IMPLANT DENTISTRY AND RELATED RESEARCH
(2022)
Article
Chemistry, Multidisciplinary
Lejla Redzepagic-Vrazalica, Elmedin Mesic, Nedim Pervan, Vahidin Hadziabdic, Muamer Delic, Mirza Glusac
Summary: This study found that the design of orthodontic mini-implants significantly affects their primary stability and pull-out force. Despite using the same material and insertion method, the tested implants differed in design, which was the main focus of the research.
APPLIED SCIENCES-BASEL
(2021)
Article
Dentistry, Oral Surgery & Medicine
Lan Feng, Haida Chen, Ziyun Chen, Yan Chen, Xinhua Gu
Summary: This study aimed to evaluate the associations between cortical bone-to-implant contact, bone microstructure derived from cone-beam computed tomography, and the primary stability of the implant. The results showed that preoperative cone-beam CT measurements could predict implant insertion torque and primary stability values.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Yu-Sung Choi, In-Seok Song, Moon-Young Kim, Ho-Kyung Lim, Li Chongyang, Ji Suk Shim
Summary: This study aimed to evaluate the effect of aging on the changes in implant stability over time following implant placement. The results showed that the stability of implants in elderly patients is not related to age, but rather to the engagement of the implant with the bone.
CLINICAL ORAL IMPLANTS RESEARCH
(2023)
Article
Dentistry, Oral Surgery & Medicine
Alessandra Julie Schuster, Joao Luiz Bittencourt de Abreu, Natalia Marcumini Pola, Lukasz Witek, Paulo G. Coelho, Fernanda Faot
Summary: This study evaluated peri-implant bone formation of titanium implants using an in vivo rat model with and without uncontrolled diabetes mellitus. The results showed that the hydrophilic surface was able to counteract the adverse effects of diabetes at early osseointegration periods, but the metabolic systemic impairment caused by diabetes overcame the surface treatment effect after 28 days, leading to impaired osseointegration in both hydrophilic and hydrophobic implants.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Oncology
Chunan Zhang, Xu Zhao, Shichong Qiao, Xiaomeng Zhang, Hongchang Lai, Yingxin Gu
Summary: This study compared tissue alterations in fresh extraction sockets between bone-level and tissue-level implants with different neck designs. It was found that different neck designs had little effect on bone remodeling in fresh extraction sockets, but bone-level implants exhibited longer biological width.
ANNALS OF TRANSLATIONAL MEDICINE
(2021)
Article
Chemistry, Physical
Hugo Robertson Sant'Anna, Marcio Zaffalon Casati, Mounir Colares Mussi, Fabiano Ribeiro Cirano, Suzana Peres Pimentel, Fernanda Vieira Ribeiro, Monica Grazieli Correa
Summary: This study found that the use of implants with modified macrogeometry can improve biomechanical retention and positively modulate important bone markers in the peri-implant bone tissue under diabetic conditions.
Article
Engineering, Biomedical
Chester Jar, Andrew Archibald, Monica Gibson, Lindsey Westover
Summary: This study evaluates the ASIST technique for assessing the stability of dental implants. The results show that the ASIST technique can reliably measure the interfacial stiffness of dental implants, which is not significantly influenced by different abutment types. This method may provide an improved non-invasive way to measure the stability of dental implants.
JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS
(2024)
Article
Dentistry, Oral Surgery & Medicine
Rong Cai, Yi Liu, Xinge Wang, Hongbo Wei, Jin Wang, Yanze Cao, Jiaqi Lei, Dehua Li
Summary: This study investigated the healing of soft tissue after clinical probing in a situation of peri-implant mucositis. The results showed that clinical probing may lead to apical migration of the junctional epithelium in peri-implant mucositis, accompanied by inflammation and cell proliferation.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Engineering, Biomedical
Nasim Golafshan, Koen Willemsen, Firoz Babu Kadumudi, Elke Vorndran, Alireza Dolatshahi-Pirouz, Harrie Weinans, Bart C. H. van der Wal, Jos Malda, Miguel Castilho
Summary: The study introduces a novel regenerative hip implant fabricated through a one-step process based on patient-specific design and load-bearing properties. The implant, made using a flexible, bone-inducing biomaterial and extrusion-assisted 3D printing, shows mechanical stability and degradation resistance. It can be fixed with metallic screws to host bone and withstand physiological loads, even after losing approximately 40% of its initial mass. Overall, the hip implant offers an innovative solution for hip dysplasia treatment with regenerative properties.
ADVANCED HEALTHCARE MATERIALS
(2021)