4.5 Article

Copper-Catalyzed Formation of C-O Bonds by Oxidative Coupling of Benzylic Alcohols with Ethers

Journal

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2014, Issue 31, Pages 6850-6853

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201402885

Keywords

Synthetic methods; Cross-coupling; Oxidation; Copper; Peroxides; Ethers; Alcohols

Funding

  1. National Nature Science Foundation of China (NSFC) [21302013]
  2. Nature Science Foundation of Jiangsu Province [BK2012207]
  3. Nature Science Foundation of Jiangsu Educational Department [12KJA150001, 12KJB150001]

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The copper-catalyzed formation of C-O bonds by oxidative coupling of benzylic alcohols with ethers was realized in open air. A series of a-acyloxy ethers were obtained in good yields with aqueous tert-butyl hydroperoxide as the oxidant.

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