Copper-Catalyzed Aerobic Dehydrogenation of C-C to C=C Bonds in the Synthesis of Pyridazinones

A Copper-Catalyzed Aerobic Cascade Dehydrogenative- Dehalogenative Reaction

(2013) Lei Liang et al.   ADVANCED SYNTHESIS & CATALYSIS

Aerobic Oxidative Heck/Dehydrogenation Reactions of Cyclohexenones: Efficient Access tometa-Substituted Phenols

(2013) Yusuke Izawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation

(2013) Lei Liang et al.   ORGANIC LETTERS

Overcoming the “Oxidant Problem”: Strategies to Use O2 as the Oxidant in Organometallic C–H Oxidation Reactions Catalyzed by Pd (and Cu)

(2012) Alison N. Campbell et al.   ACCOUNTS OF CHEMICAL RESEARCH

Recent advances in copper-catalyzed dehydrogenative functionalization via a single electron transfer (SET) process

(2012) Chun Zhang et al.   CHEMICAL SOCIETY REVIEWS

Diazine Indole Acetic Acids as Potent, Selective, and Orally Bioavailable Antagonists of Chemoattractant Receptor Homologous Molecule Expressed on Th2 Cells (CRTH2) for the Treatment of Allergic Inflammatory Diseases

(2012) Neelu Kaila et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of pyridazin-3-one derivatives as potent, selective histamine H3 receptor inverse agonists with robust wake activity

(2011) Robert L. Hudkins et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Dehydrogenation and Related Reactions Catalyzed by Iridium Pincer Complexes

(2011) Jongwook Choi et al.   CHEMICAL REVIEWS

Discovery and Characterization of 6-{4-[3-(R)-2-Methylpyrrolidin-1-yl)propoxy]phenyl}-2H-pyridazin-3-one (CEP-26401, Irdabisant): A Potent, Selective Histamine H3Receptor Inverse Agonist

(2011) Robert L. Hudkins et al.   JOURNAL OF MEDICINAL CHEMISTRY

Optimization of 5-Pyridazin-3-one Phenoxypropylamines as Potent, Selective Histamine H3 Receptor Antagonists with Potent Cognition Enhancing Activity

(2011) Ming Tao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Cyclic Enones via Direct Palladium-Catalyzed Aerobic Dehydrogenation of Ketones

(2011) Tianning Diao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Aerobic Dehydrogenation of Substituted Cyclohexanones to Phenols

(2011) Y. Izawa et al.   SCIENCE

Direct aerobic α,β-dehydrogenation of aldehydes and ketones with a Pd(TFA)2/4,5-diazafluorenone catalyst

(2011) Tianning Diao et al.   Chemical Science

General palladium-catalyzed aerobic dehydrogenation to generate double bonds

(2011) Weiming Gao et al.   Chemical Science

Synthesis, characterization and antihypertensive activity of pyridazinone derivatives

(2010) Anees A. Siddiqui et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

One-Pot Syntheses of α,β-Unsaturated Carbonyl Compounds through Palladium-Mediated Dehydrogenation of Ketones, ­Aldehydes, Esters, Lactones and Amides

(2010) Jacques Muzart   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Novel anti-inflammatory agents based on pyridazinone scaffold; design, synthesis and in vivo activity

(2008) Khaled Abouzid et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery and optimization of pyridazinone non-nucleoside inhibitors of HIV-1 reverse transcriptase

(2008) Zachary K. Sweeney et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Adenosine Receptor Antagonists:  Translating Medicinal Chemistry and Pharmacology into Clinical Utility

(2008) Pier Giovanni Baraldi et al.   CHEMICAL REVIEWS

Total Synthesis of (+)-Azaspiracid-1. An Exhibition of the Intricacies of Complex Molecule Synthesis

(2008) David A. Evans et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY