Journal
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Volume 2012, Issue 19, Pages 3658-3664Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejoc.201200312
Keywords
Medicinal chemistry; Structural biology; Drug conjugates; Aggregation; Micelles; Nanostructures; Surfactants; Cholesterol
Categories
Funding
- Department of Science and Technology (DST), New Delhi
- Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore
Ask authors/readers for more resources
Taurine conjugates of two cholic acid derived oligomers with different spacers between the cholic acid units were synthesized. These molecules self-assemble in aqueous media. The critical micelle concentration (CMC) values were measured by using fluorescence spectroscopic analysis and the aggregates were characterized by dynamic light scattering and electron microscopy. The cooperativity of the cholic acid units in these tetramers to solubilize cholesterol was investigated. The ability of these molecules to act as nanocarriers for liphophilic dyes was also studied.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available