Synthetic Methods for Fluorinated Olefins

Copper mediated defluorinative allylic alkylation of difluorohomoallyl alcohol derivatives directed to an efficient synthetic method for (Z)-fluoroalkene dipeptide isosteres

(2011) Daisuke Watanabe et al.   JOURNAL OF FLUORINE CHEMISTRY

X-ray Crystal Structure and Binding Mode Analysis of HumanS-Adenosylhomocysteine Hydrolase Complexed with Novel Mechanism-Based Inhibitors, Haloneplanocin A Analogues

(2011) Kang Man Lee et al.   JOURNAL OF MEDICINAL CHEMISTRY

Palladium-Catalyzed Tandem Fluorination and Cyclization of Enynes

(2011) Haihui Peng et al.   ORGANIC LETTERS

Stereoselective Synthesis of Both Stereoisomers of β-Fluorostyrene Derivatives from a Common Intermediate

(2011) Grégory Landelle et al.   ORGANIC LETTERS

Synthesis of Monofluoroalkenes via the Activation of Allylic C-F Bonds: A Novel Route to β-Aminofluoroalkenes Using Pd-Catalyzed Allylic Amination Reactions of 3,3-Difluoropropenes

(2011) Jean-François Paquin   SYNLETT

Copper-free defluorinative alkylation of allylic difluorides through Lewis acid-mediated C–F bond activation

(2011) Hikaru Yanai et al.   TETRAHEDRON LETTERS

Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL

(2010) Rajamalleswaramma Jogireddy et al.   ChemMedChem

Property and Reactivity of Fluoro(silyl)acetylenes and Fluoro(stannyl)acetylenes

(2010) Masahiro Shiosaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Difluoromethyl 2-Pyridyl Sulfone: A Newgem-Difluoroolefination Reagent for Aldehydes and Ketones

(2010) Yanchuan Zhao et al.   ORGANIC LETTERS

Convergent synthesis of functionalized fluoroallylamines by the Julia–Kocienski reaction

(2010) Charlène Calata et al.   TETRAHEDRON

Fluoroalkene modification of mercaptoacetamide-based histone deacetylase inhibitors

(2009) Satoshi Osada et al.   BIOORGANIC & MEDICINAL CHEMISTRY

C−F Bond Activation in Organic Synthesis

(2009) Hideki Amii et al.   CHEMICAL REVIEWS

Synthesis of Amide-Type Fluoroalkene Dipeptide Isosteres by an Intramolecular Redox Reaction

(2009) Yoko Yamaki et al.   JOURNAL OF ORGANIC CHEMISTRY

α-Fluorovinyl Weinreb Amides and α-Fluoroenones from a Common Fluorinated Building Block

(2009) Arun K. Ghosh et al.   JOURNAL OF ORGANIC CHEMISTRY

Diethylzinc-Mediated One-Step Stereoselective Synthesis of α-Fluoroacrylates from Aldehydes and Ketones. Two Different Pathways Depending on the Carbonyl Partner

(2009) G. Lemonnier et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Fluoroalkene Dipeptide Isosteres by an Intramolecular Redox Reaction UtilizingN-Heteorocyclic Carbenes (NHCs)

(2009) Yoko Yamaki et al.   JOURNAL OF ORGANIC CHEMISTRY

Peptide bond mimicry by (E)-alkene and (Z)-fluoroalkene peptide isosteres: synthesis and bioevaluation of α-helical anti-HIV peptide analogues

(2009) Shinya Oishi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis and biological evaluation of selective CXCR4 antagonists containing alkene dipeptide isosteres

(2009) Tetsuo Narumi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Stereocontrolled Approach to Bromofluoroalkenes and Their Use for the Synthesis of Tri- and Tetrasubstituted Fluoroalkenes

(2009) Grégory Landelle et al.   ORGANIC LETTERS

Stereocontrolled Access to Unsymmetrical 1,1-Diaryl-2-fluoroethenes

(2009) Grégory Landelle et al.   ORGANIC LETTERS

Regio- and Stereoselective Synthesis of Fluoroalkenes by Directed Au(I) Catalysis

(2009) Benjamin C. Gorske et al.   ORGANIC LETTERS

Efficient Nucleophilic Fluoromethylation and Subsequent Transformation of Alkyl and Benzyl Halides Using Fluorobis(phenylsulfonyl)methane

(2009) G. K. Surya Prakash et al.   ORGANIC LETTERS

Fluorination of Boronic Acids Mediated by Silver(I) Triflate

(2009) Takeru Furuya et al.   ORGANIC LETTERS

Scope and limitations of the Julia–Kocienski reaction with fluorinated sulfonylesters

(2009) Charlène Calata et al.   TETRAHEDRON

A general preparation of (Z)-1-fluorostilbene derivatives for the design of conformationally restricted peptidomimetics

(2009) David R. Williams et al.   TETRAHEDRON LETTERS

Highly Efficient and Stereoselective Julia-Kocienski Protocol for the Synthesis of α-Fluoro-α,β-unsaturated Esters and Weinreb Amides Employing 3,5-Bis(trifluoromethyl)phenyl (BTFP) Sulfones

(2008) Diego A. Alonso et al.   ADVANCED SYNTHESIS & CATALYSIS

A Convenient Method for the Synthesis of (Z)-α-Fluoroacrylates: Lewis Base-catalyzed Carbonyl Fluoroolefination Using Fluoro(trimethylsilyl)ketene Ethyl Trimethylsilyl Acetal

(2008) Makoto Michida et al.   CHEMISTRY LETTERS

Diastereoselective synthesis of highly functionalized fluoroalkene dipeptide isosteres and its application to Fmoc-based solid-phase synthesis of a cyclic pentapeptide mimetic

(2008) Tetsuo Narumi et al.   TETRAHEDRON