Squalenoyl Gemcitabine Monophosphate: Synthesis, Characterisation of Nanoassemblies and Biological Evaluation

Interaction of a new anticancer prodrug, gemcitabine–squalene, with a model membrane

(2010) Barbara Pili et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Long circulation and cytotoxicity of PEGylated gemcitabine and its potential for the treatment of pancreatic cancer

(2010) Mallaredy Vandana et al.   BIOMATERIALS

Squalenoyl nucleoside monophosphate nanoassemblies: New prodrug strategy for the delivery of nucleotide analogues

(2010) Joachim Caron et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthesis and in vitro cytotoxic activity on human anaplastic thyroid cancer cells of lipoamino acid conjugates of gemcitabine

(2010) Rosario Pignatello et al.   DRUG DEVELOPMENT RESEARCH

Transmembrane diffusion of gemcitabine by a nanoparticulate squalenoyl prodrug: An original drug delivery pathway

(2010) L. Bildstein et al.   JOURNAL OF CONTROLLED RELEASE

Extracellular-protein-enhanced cellular uptake of squalenoyl gemcitabine from nanoassemblies

(2010) Lucien Bildstein et al.   Soft Matter

Freeze-drying of squalenoylated nucleoside analogue nanoparticles

(2009) L. Bildstein et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lipophilic Modifications to Dinucleoside Polyphosphates and Nucleotides that Confer Antagonist Properties at the Platelet P2Y12Receptor

(2008) James G. Douglass et al.   JOURNAL OF MEDICINAL CHEMISTRY

Preclinical Toxicology (Subacute and Acute) and Efficacy of a New Squalenoyl Gemcitabine Anticancer Nanomedicine

(2008) L. H. Reddy et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Discovery of New Hexagonal Supramolecular Nanostructures Formed by Squalenoylation of an Anticancer Nucleoside Analogue

(2008) Patrick Couvreur et al.   Small

Synthesis of Isotopically Labeled P-Site Substrates for the Ribosomal Peptidyl Transferase Reaction

(2007) Minghong Zhong et al.   JOURNAL OF ORGANIC CHEMISTRY