Article
Dentistry, Oral Surgery & Medicine
Madonna Rofaeel, Jeffrey Chi-Fai Chow, Iacopo Cioffi
Summary: This study found that individuals with higher levels of trait anxiety exhibited increased masseter muscle activity and intensity of wake-time tooth clenching episodes. However, no between-group differences were found in postural activity and duration of tooth clenching episodes.
CLINICAL ORAL INVESTIGATIONS
(2021)
Article
Neurosciences
Gabriele Russo, Xavier Helluy, Mehdi Behroozi, Denise Manahan-Vaughan
Summary: The study proposes a habituation strategy for awake rats undergoing fMRI, which enables stable image acquisition with low motion artifacts by gradually training the rats over a period of three weeks. Effective habituation results in low stress levels and minimal head motion artifacts during fMRI, allowing for precise brain mapping of BOLD signals and supporting the discrimination of cognitive processes without stress confounds.
FRONTIERS IN NEUROSCIENCE
(2021)
Article
Chemistry, Analytical
Lindsay C. Fadel, Ivany Patel, Jonathan Romero, I-Chih Tan, Shelli R. Kesler, Vikram Rao, S. A. Amali S. Subasinghe, Russell S. Ray, Jason T. Yustein, Matthew J. Allen, Brian W. Gibson, Justin J. Verlinden, Stanley Fayn, Nicole Ruggiero, Caitlyn Ortiz, Elizabeth Hipskind, Aaron Feng, Chijindu Iheanacho, Alex Wang, Robia G. Pautler
Summary: This article introduces a newly designed mouse holder that allows for awake in vivo mouse imaging and demonstrates significant differences in P-31 spectra, MEMRI transport rates, and rs-fMRI connectivity between anesthetized and awake animals. This highlights the importance of using unanesthetized animals in functional studies.
Article
Multidisciplinary Sciences
Kyle M. Gilbert, Justine C. Clery, Joseph S. Gati, Yuki Hori, Kevin D. Johnston, Alexander Mashkovtsev, Janahan Selvanayagam, Peter Zeman, Ravi S. Menon, David J. Schaeffer, Stefan Everling
Summary: The authors present an MRI hardware and image-processing pipeline for simultaneous functional imaging of two marmosets, showing increased brain activation in the face-patch network when the monkeys interact in person compared to viewing a pre-recorded video. This method offers a wide range of possibilities for studying social function and dysfunction in non-human primate models.
NATURE COMMUNICATIONS
(2021)
Review
Neurosciences
Craig F. Ferris
Summary: This review primarily focuses on the many applications of rodents in awake functional MRI, including pharmacological MRI, drugs of abuse, sensory evoked stimuli, brain disorders, pain, social behavior, and fear. In addition, the article also mentions the applications of other species such as voles, rabbits, cats, dogs, and rhesus macaques in this field.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Joseph R. Whittaker, Jessica J. Steventon, Marcello Venzi, Kevin Murphy
Summary: This study used fMRI to characterize the spatiotemporal dynamics of the flow response to the TCR challenge, and proposed that TCR challenge fMRI is a promising method for mapping spatial variability in dCA.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Neurosciences
Francesca Mandino, Stella Vujic, Joanes Grandjean, Evelyn M. R. Lake
Summary: This systematic review focuses on the development of awake mouse blood oxygen level dependent functional magnetic resonance imaging (fMRI) and discusses its importance in neuroscience research. The review includes an analysis of 30 articles and provides conclusions and recommendations.
Article
Anatomy & Morphology
Qiong Li, Nanyin Zhang
Summary: There are sex-related differences in brain disorders and psychophysiological traits, and it is important to understand these differences in brain function between males and females in humans and animal models. However, little is known about the differences in brain-wide functional connectivity patterns between male and female rats, despite efforts to address sex differences in behaviors and disease models in rodents.
BRAIN STRUCTURE & FUNCTION
(2023)
Article
Clinical Neurology
Lei Li, Jiayu Liu, Fenxiong Liang, Haidong Chen, Rungen Zhan, Shengli Zhao, Tiao Li, Yongjun Peng
Summary: This study used rs-fMRI measures to investigate changes in brain function activity in patients with dysphagia after cerebral infarction (DYS) and their correlations with dysphagia severity. The results showed that the changes in brain function activity in the right temporal and left parietal lobes were associated with dysphagia severity in DYS patients.
FRONTIERS IN NEUROLOGY
(2022)
Article
Biochemical Research Methods
Clement Brunner, Micheline Grillet, Alan Urban, Botond Roska, Gabriel Montaldo, Emilie Mace
Summary: This protocol describes how to use functional ultrasound imaging to track brain-wide activity in awake head-fixed mice, including setting up the imaging system, establishing a cranial window, and extracting activity traces. Neuroscientists can observe global brain processes in mice using this method.
Article
Biology
Andrea Ciorba, Stavros Hatzopoulos, Cristina Cogliandolo, Chiara Bianchini, Martina Renna, Luca Perrucci, Magdalena Skarzynska, Piotr Henryk Skarzynski, Paolo Campioni, Corrado Cittanti, Aldo Carnevale, Melchiore Giganti, Stefano Pelucchi
Summary: The study utilized fMRI to evaluate brain maps generated from healthy individuals' response to olfactory stimuli, revealing that the left anterior insula is primarily activated by odorous stimuli and other cortical areas are also involved.
Article
Neurosciences
Rita Gil, Francisca F. Fernandes, Noam Shemesh
Summary: The study found that using ultrafast fMRI technology can more accurately map neuroplasticity in the whole brain, successfully detecting temporal modulations of neural activity in the mouse visual pathway.
Article
Neurosciences
Xin Zhang, Jiayue Liu, Yang Yang, Shijie Zhao, Lei Guo, Junwei Han, Xintao Hu
Summary: The study examined the test-retest reliability of dynamic functional connectivity (dFC) in functional magnetic resonance imaging (fMRI) under natural viewing condition, revealing significantly improved reliability compared to resting state. This suggests that naturalistic paradigms may enhance the study of functional brain networks using fMRI.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Yuki Hori, Justine C. Clery, David J. Schaeffer, Ravi S. Menon, Stefan Everling
Summary: The study utilized hierarchical clustering of interareal blood oxygen level-dependent signals in New World common marmoset monkeys to investigate their frontoparietal network organization, revealing similarities with macaque monkeys and supporting the presence of parallel frontoparietal processing streams in marmosets. These findings highlight the importance of the frontoparietal network in cognitive functions and validate the common marmoset as a valuable experimental animal model.
Article
Neurosciences
Alice E. Thackray, Elanor C. Hinton, Turki M. Alanazi, Abdulrahman M. Dera, Kyoko Fujihara, Julian P. Hamilton-Shield, James A. King, Fiona E. Lithander, Masashi Miyashita, Julie Thompson, Paul S. Morgan, Melanie J. Davies, David J. Stensel
Summary: Acute exercise can suppress appetite and alter food-cue reactivity, but the impact of exercise-induced changes in cerebral blood flow (CBF) on the blood-oxygen-level-dependent (BOLD) signal during appetite-related tasks is unclear. This study found that acute running led to decreased subjective appetite ratings and increased food-cue reactivity, independent of CBF changes.
HUMAN BRAIN MAPPING
(2023)