Article
Medicine, General & Internal
Paola De La Parra-Colin, Karen Palacios-Aguirre, Andrea Perez-Pria-Kasusky, Rolando Espinosa-Morales, Alberto Hidalgo-Bravo
Summary: The study found that tear meniscus osmolarity measured by TearLab (R) showed low sensitivity, low specificity, and limited agreement with the TFOS DEWS II composite reference standard for dry eye disease diagnosis in patients with rheumatoid arthritis.
Review
Medicine, General & Internal
Anthony J. Bron, Catherine Willshire
Summary: Systemic dehydration is common in the elderly, leading to high morbidity and mortality. Tear osmolarity may serve as a potential indicator of systemic dehydration, but further research is needed for confirmation.
Article
Medicine, General & Internal
Anna Maria Roszkowska, Leandro Inferrera, Rosaria Spinella, Elisa Imelde Postorino, Romana Gargano, Giovanni Wiliam Oliverio, Pasquale Aragona
Summary: This study evaluated the clinical efficacy and safety of a new-generation ophthalmic solution in patients with moderate to severe dry eye disease. The results showed significant improvements in ocular surface parameters and no adverse events.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Maria T. Iradier, Maria Angeles del Buey, Cristina Peris-Martinez, Priscilla Cedano, David P. Pinero
Summary: This study found that IPL-based treatment can significantly improve tear film osmolarity and meibum quality in dry eyes associated with Meibomian gland dysfunction, and the potential therapeutic effect can be predicted. A linear model considering MGD level, OSDI, and NIBUT can be used to predict treatment outcomes before therapy.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Ophthalmology
Jack Greiner, Gui-shuang Ying, Maxwell Pistilli, Maureen G. Maguire, Penny A. Asbell
Summary: The purpose of this study was to determine the relationships between tear osmolarity levels and the severity of signs and symptoms of dry eye disease, as well as the changes in tear osmolarity with changes in signs and symptoms. The study found that tear osmolarity was weakly correlated with dry eye disease signs, and the changes in tear osmolarity were not associated with changes in signs and symptoms of dry eye disease.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Ophthalmology
Sunil Shah, Debarun Dutta, Ankur Barua, Ludger Hanneken, Shehzad A. Naroo
Summary: The study aimed to determine the effects of Tixel (R) treatment on dry eye disease. The results showed that Tixel treatment significantly improved dry eye symptoms and had no adverse events.
CONTACT LENS & ANTERIOR EYE
(2023)
Article
Ophthalmology
Azadeh Tavakoli, Maria Markoulli, Judith Flanagan, Eric Papas
Summary: This study found that both TearLab and I-PEN demonstrated reasonable accuracy and repeatability at mid-range osmolarities, but repeatability generally declined at higher and lower levels. While TearLab showed consistent accuracy across the osmolarity range, measurement errors for I-PEN noticeably increased outside the mid-range. In vivo, both instruments displayed poor repeatability.
OPHTHALMIC AND PHYSIOLOGICAL OPTICS
(2022)
Article
Multidisciplinary Sciences
Jon Roger Eidet, Xiangjun Chen, Sten Raeder, Reza A. Badian, Tor P. Utheim
Summary: This study investigated the seasonal variations of symptoms and signs of dry eye disease in Norway. It found that the severity level and self-reported symptoms of dry eye did not differ between seasons, but some parameters for assessing dry eye (such as Schirmer I and tear meniscus height) showed seasonal variations.
SCIENTIFIC REPORTS
(2022)
Review
Ophthalmology
Hugo Pena-Verdeal, Carlos Garcia-Resua, Jacobo Garcia-Queiruga, Belen Sabucedo-Villamarin, Eva Yebra-Pimentel, Maria Jesus Giraldez
Summary: The osmolarity of tear film varies throughout the day and can be influenced by factors such as time, health condition, and environment. Clinicians should consider the diurnal variations in tear film osmolarity when making diagnoses to ensure accuracy.
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2023)
Article
Environmental Sciences
Naika Meili, Athanasios Paschalis, Gabriele Manoli, Simone Fatichi
Summary: Urban heat islands (UHIs) are extensively studied, but there is less research on urban-rural differences in humidity. This study quantifies the seasonal and diurnal patterns of urban dry or moisture islands (UDIs, UMIs) using global temperature and humidity measurements. The results show that absolute UDI is largest during daytime, while relative UDI is largest during night. These findings are essential for understanding the impacts of humidity on urban ecology and building energy consumption.
ENVIRONMENTAL RESEARCH LETTERS
(2022)
Article
Otorhinolaryngology
Alper Yenigun, Ahmet Elbay, Abdullah Ozdem, Havvanur Bayraktar, Omer Faruk Ozer, Remzi Dogan, Orhan Ozturan
Summary: This study found that tear and nasal secretion osmolarity was significantly higher in allergic rhinitis patients compared to those with acute upper respiratory tract infections and healthy individuals. However, there was no difference in blood osmolarity between the groups. Additionally, allergic rhinitis patients had shorter Schirmer test results than those with acute upper respiratory tract infections and healthy participants.
ENT-EAR NOSE & THROAT JOURNAL
(2021)
Article
Multidisciplinary Sciences
Jongyeop Park, Youngjoo Choi, Gyule Han, Eunhae Shin, Jisang Han, Tae-Young Chung, Dong Hui Lim
Summary: This retrospective study found that tear osmolarity was significantly higher in patients with dry eye disease, and was negatively correlated with tear break-up time and the Schirmer test, while positively correlated with Ocular Surface Disease Index symptom score. A cut-off value of 318 mOsm/L showed high sensitivity and specificity for diagnosing dry eye disease. The I-Pen osmometer showed good performance in diagnosing dry eye disease in a clinical setting.
SCIENTIFIC REPORTS
(2021)
Article
Ophthalmology
Martina Menchini, Francesco Sartini, Michele Figus, Giovanna Gabbriellini
Summary: In patients with moderate to severe primary Sjogren syndrome-related dry eye disease, short-term treatment with pulsed low-dose hydrocortisone sodium phosphate eye drops improves symptoms and signs of dry eye disease without affecting intraocular pressure.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2023)
Article
Multidisciplinary Sciences
Huiqian Zhang, Gary D. Egbert, Qinghua Huang
Summary: The water content in the mantle transition zone is found to be very low, which has important implications for material circulation and partial melting in the mantle. However, further research is needed in this field to fully understand its significance.
Article
Ophthalmology
Maria H. J. Hollander, Jan Willem R. Pott, Konstantina Delli, Arjan Vissink, Rutger H. Schepers, Johan Jansma
Summary: The study found that upper blepharoplasty, with or without removal of a strip of orbicularis oculi muscle, can alleviate dry eye symptoms in patients, while not significantly affecting tear dynamics.
ACTA OPHTHALMOLOGICA
(2022)
