Article
Oncology
Yolanda Ribas, Montse Martin-Baranera, Ladislao Cayetano, Carles Maristany, Josep Bargallo, Salvadora Delgado, Arantxa Munoz-Duyos
Summary: This study aimed to estimate the incidence and characterize the low anterior resection syndrome (LARS) in patients after rectal cancer surgery, and found that bowel dysfunction is common and has a significant impact on patients' quality of life.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Gastroenterology & Hepatology
Qiyuan Qin, Binjie Huang, Aiwen Wu, Jiale Gao, Xinzhi Liu, Wuteng Cao, Tenghui Ma, Yingyi Kuang, Jirui Guo, Qian Wu, Biyan Shao, Qi Guan, Hongwei Yao, Xiaoyan Zhang, Hui Wang
Summary: This study aimed to develop and validate a risk model to improve the prediction of major bowel dysfunction after restorative rectal cancer resection with neoadjuvant radiotherapy. Clinical characteristics and imaging parameters were evaluated using machine learning algorithms, and the prediction model was constructed based on logistic regression. The model demonstrated high accuracy in predicting major bowel dysfunction.
Article
Surgery
Stephan Robitaille, Anna Wang, Sender Liberman, Patrick Charlebois, Barry Stein, Julio F. Fiore, Liane S. Feldman, Lawrence Lee
Summary: This study evaluates the impact of untreated rectal cancer on bowel dysfunction and the relationship between pre-treatment and post-treatment function. It finds that pretreatment bowel dysfunction is common in rectal cancer patients, especially in older and male patients. Furthermore, pretreatment dysfunction can predict postoperative function.
Article
Medicine, General & Internal
Andrea Cercek, Melissa Lumish, Jenna Sinopoli, Jill Weiss, Jinru Shia, Michelle Lamendola-Essel, Imane H. El Dika, Neil Segal, Marina Shcherba, Ryan Sugarman, Zsofia Stadler, Rona Yaeger, J. Joshua Smith, Benoit Rousseau, Guillem Argiles, Miteshkumar Patel, Avni Desai, Leonard B. Saltz, Maria Widmar, Krishna Iyer, Janie Zhang, Nicole Gianino, Christopher Crane, Paul B. Romesser, Emmanouil P. Pappou, Philip Paty, Julio Garcia-Aguilar, Mithat Gonen, Marc Gollub, Martin R. Weiser, Kurt A. Schalper, Luis A. Diaz
Summary: This study found that mismatch repair-deficient, locally advanced rectal cancer is highly sensitive to PD-1 blockade. Additionally, no adverse events of grade 3 or higher have been reported, and no cases of progression or recurrence have been observed. Longer follow-up is needed to assess the duration of response.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Gastroenterology & Hepatology
Sanne J. Verkuijl, Christiaan Hoff, Edgar J. B. Furnee, Wendy Kelder, Daniel A. Hess, Fennie Wit, Ronald J. Zijlstra, Monika Trzpis, Paul M. A. Broens
Summary: This study investigated the long-term relation between anastomotic height after rectal cancer surgery and postoperative bowel function problems, and found that anastomotic height was associated with constipation, fecal incontinence, and major low anterior resection syndrome. The results of this study may serve as a guide for clinicians to effectively screen and treat incontinence and constipation during patient follow-up after rectal cancer surgery.
DISEASES OF THE COLON & RECTUM
(2023)
Article
Oncology
REACCT Collaborative
Summary: A substantial proportion of patients with early-onset rectal cancer who undergo surgery report persistent impairment of functional status, particularly in bowel function. It is recommended to routinely record functional outcomes and assess them alongside oncological parameters during follow-up.
FRONTIERS IN ONCOLOGY
(2022)
Article
Gastroenterology & Hepatology
Jeongyoon Moon, Richard Garfinkle, Phyllis Zelkowitz, Sophie Dell'Aniello, Carol-Ann Vasilevsky, Paul Brassard, Marylise Boutros
Summary: This study investigated the incidence of mental health disorders in patients who underwent restorative proctectomy for rectal cancer and its association with bowel symptoms. The study found that incident mental health disorders were common in rectal cancer survivors after surgery, and the presence of bowel and urinary functional impairment significantly increased the risk of poor psychological outcomes.
DISEASES OF THE COLON & RECTUM
(2023)
Review
Medicine, General & Internal
Federica De Muzio, Roberta Fusco, Carmen Cutolo, Giuliana Giacobbe, Federico Bruno, Pierpaolo Palumbo, Ginevra Danti, Giulia Grazzini, Federica Flammia, Alessandra Borgheresi, Andrea Agostini, Francesca Grassi, Andrea Giovagnoni, Vittorio Miele, Antonio Barile, Vincenza Granata
Summary: Rectal cancer is a highly lethal malignancy and surgery is the most common treatment option. The choice of surgical approach aims to maximize function while minimizing the risk of recurrence, and is determined by a multidisciplinary team assessing patient and tumor characteristics. Total mesorectal excision, including both low anterior resection and abdominoperineal resection, remains the standard of care for rectal cancer. Rating: 8 out of 10.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Multidisciplinary Sciences
Fan Liu, Peng Guo, Quan Wang, Fujun Chen, Wenyong Wu, Xiangqian Su, Guiying Wang, Zhouman Yu, Jianlong Jiang, Feng Liang, Dechang Diao, Zhikang Chen, Yuanting Liu, Fanqiang Meng, Ning Ning, Yingjiang Ye
Summary: This study aims to investigate the incidence of LARS after anus-preserving surgery (APS) and the relationship between bowel volume loss and bowel function. The results showed that the length of excised bowel was positively correlated with bowel function, and a shorter length of the proximal margin (LPM) had a greater negative impact on bowel function. Controlling LPM to <10 cm may help improve postoperative bowel function.
Article
Surgery
Supparerk Laohawiriyakamol, Siripong Chewatanakornkul, Worawit Wanichsuwan, Sakchai Ruangsin, Somkiat Sunpaweravong, Tanan Bejrananda
Summary: Urogenital dysfunction is a common complication after surgery for sigmoid colon or rectal cancers, and it may result from various causes. This study evaluated urogenital dysfunction and associated factors after laparoscopic surgery at different follow-up times. The results showed that voiding function improved, but sexual function deteriorated, especially in male patients. Age <= 60 years and postoperative complications were strongly associated with male sexual dysfunction.
ASIAN JOURNAL OF SURGERY
(2023)
Review
Biochemistry & Molecular Biology
Patrycja Klos, Siarhei A. Dabravolski
Summary: Inflammatory bowel disease and colorectal cancer are closely related to mitochondrial mutations and dysfunctions, and recent research has proposed mitochondria-targeted therapeutic approaches to cure IBD and prevent CRC progression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Gastroenterology & Hepatology
Giovanni Marasco, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, Mohammed Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yagci, Husnu Pullukcu, Berrin Yalinbas Kaya, Ali Tureyen, Ibrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Caliskan, Goksel Bengi, Esra Ergun Alis, Snezana Lukic, Meri Trajkovska, Keren Hod, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjoelund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara
Summary: This study aimed to evaluate the prevalence of gastrointestinal symptoms and post-COVID-19 disorders of gut-brain interaction among hospitalized patients with SARS-CoV-2 infection. The results showed that patients with COVID-19 had higher rates of gastrointestinal symptoms on hospital admission and lower rates of constipation and hard stools at 12 months post-infection compared to the control group. Additionally, the rate of irritable bowel syndrome was significantly higher in patients with COVID-19 than in controls.
Article
Neurosciences
Jie Liu, Chaolan Lv, Wei Wang, Yizhou Huang, Bo Wang, Jiashuang Tian, Chenyu Sun, Yue Yu
Summary: This study found that a 6-week slow, deep breathing (SDB) intervention improved symptoms and altered rectal sensation in constipation-predominant IBS (IBS-C) patients. Additionally, SDB enhanced vagal activity, suggesting that the effect of SDB on IBS-C may be due to mechanisms involving autonomic responses.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Pascal Rousset, Guillaume Buisson, Jean-Christophe Lega, Mathilde Charlot, Colin Gallice, Eddy Cotte, Laurent Milot, Francois Golfier
Summary: Assessing MRI rectal and pararectal signs can accurately predict the need for segmental resection versus a more conservative approach such as shaving for rectal lesion management. The study found that specific rectal signs and the sacro-recto-genital septum pararectal sign were significantly associated with segmental resection, with nodular thickness and circumference being the most predictive signs. These signs, when combined, were predictive of segmental resection with an accuracy of 90.2%.
EUROPEAN RADIOLOGY
(2021)
Article
Gastroenterology & Hepatology
Michael F. Maalouf, Stephan Robitaille, Ruxandra Penta, Makena Pook, A. Sender Liberman, Julio F. Fiore, Liane S. Feldman, Lawrence Lee
Summary: This study used qualitative content analysis to identify the quality-of-life domains most affected by rectal cancer surgery. The findings revealed that bowel dysfunction has a wide range of impacts on quality of life, including psychological and emotional stress, challenges in social roles and relationships, physical limitations, restrictions in leisure activities, and the need for self-empowerment and adaptation to change. These results can contribute to the development of a more patient-centered quality-of-life survey and provide valuable information for preoperative counseling.
DISEASES OF THE COLON & RECTUM
(2023)
Article
Nursing
Jonathan Bayuo, Frances Kam Yuet Wong, Rose Lin, Jing Jing Su, Hammoda Abu-Odah
Summary: Living with post-burn scars is a challenging process, especially for individuals whose injuries are due to self-immolation. The findings highlight a latent yet ongoing process towards subjective recovery, and clinicians need to incorporate these processes into rehabilitation programs to provide support for burn survivors.
JOURNAL OF NURSING SCHOLARSHIP
(2023)
Article
Management
Yaqi Zhu, Yuanyuan Zhang, Frances Kam Yuet Wong, Shu-Yu Kuo, Kin Cheung, Margaret C. H. Lam, Sophia H. Hu, Zhiyin Fang, Yaqing Zhang
Summary: This study aimed to explore and compare stress, coping, professional identity, and work locus of control among new graduate nurses in Shanghai, Hong Kong, and Taipei. The results showed that newly graduated nurses in Shanghai had lower work stress and tended to choose positive coping strategies. In contrast, those in Hong Kong were more likely to adopt negative attitudes, and those in Taipei had the lowest level of professional identity and tended to have external work control.
JOURNAL OF NURSING MANAGEMENT
(2022)
Article
Environmental Sciences
Qi Liu, Ka-Yan Ho, Katherine-Ka-Wai Lam, Winsome-Yuk-Yin Lam, Eileen-Hui-Lin Cheng, Shirley-Siu-Yin Ching, Frances-Kam-Yuet Wong
Summary: Spiritual well-being is an essential aspect of health, particularly for Chinese children hospitalized with cancer who are generally non-religious. Culture significantly influences their spiritual needs, which include self-exploration, inner needs, a connection with others, and a connection with gods or fictional characters. Hope plays a key role in motivating children to continue cancer treatment. Culturally specific interventions should be developed to address their unique spiritual needs and enhance their spiritual well-being.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Geriatrics & Gerontology
Arkers Kwan Ching Wong, Frances Kam Yuet Wong, Martin Chi Sang Wong, Karen Kit Sum Chow, Dilys Kwai Sin Kwan, Dubby Yun Sang Lau
Summary: This pilot study examined the implementation and dissemination of a health-social approach intervention for community-dwelling older adults. The results showed that regular communication between the research and service teams, recruitment of participants through community centers, and seamless partnership among the health-social partnership team members facilitated the program implementation. The study suggests that the program has high potential sustainability in a real-life context.
Review
Cell Biology
Bingxin Ma, Jin Yang, Frances Kam Yuet Wong, Arkers Kwan Ching Wong, Tingting Ma, Jianan Meng, Yue Zhao, Yaogang Wang, Qi Lu
Summary: The ageing population has resulted in an increased use of artificial intelligence (AI) technologies in elderly healthcare globally. However, there is currently a lack of clarity regarding the types and roles of AI technologies in elderly healthcare. This scoping review aimed to provide a comprehensive overview of AI technologies in elderly healthcare by examining the types of AI technologies employed and identifying their roles based on existing studies. The review found that AI devices used in elderly healthcare included robots, exoskeleton devices, intelligent homes, AI-enabled health applications and wearables, voice-activated devices, and virtual reality. The roles of AI technologies identified were rehabilitation therapists, emotional supporters, social facilitators, supervisors, and cognitive promoters. The results showed that AI technologies have a promising impact on elderly healthcare, meeting the unmet care needs of older adults and demonstrating great potential for further development in this field. Future well-designed randomized controlled trials are needed to validate the roles of AI technologies in elderly healthcare.
AGEING RESEARCH REVIEWS
(2023)
Article
Medicine, General & Internal
Arkers Kwan Ching Wong, Frances Kam Yuet Wong, Karen Kit Sum Chow, Siu Man Wong, Jonathan Bayuo, Annie Ka Ying Ho
Summary: This study aimed to evaluate the effects of an interactive mHealth program on quality of life among community-dwelling older adults with chronic diseases. The results showed no significant differences in the primary outcome between the mHealth+l group and the control group, confirming that there were no incremental benefits to adding interactivity in mHealth programs for older adults. However, the mHealth+l group showed improvements in secondary outcomes such as self-efficacy, systolic blood pressure, pain levels, and health services utilization.
Article
Psychology, Multidisciplinary
Qi Liu, Ka-Yan Ho, Katherine-Ka-Wai Lam, Winsome Lam, Eileen-Hui-Lin Cheng, Shirley-Siu-Yin Ching, Getaneh Mulualem Belay, Frances-Kam-Yuet Wong
Summary: The study translated and adapted the FACIT-Sp scale for Chinese childhood cancer patients, and found that the Chinese version of the adapted FACIT-Sp is a reliable and valid instrument for assessing spiritual well-being in this population. This instrument can be used for routine assessment in clinical settings.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Health Care Sciences & Services
Arkers Kwan Ching Wong, Jonathan Bayuo, Frances Kam Yuet Wong, Karen Kit Sum Chow, Siu Man Wong, Avis Cheuk Ki Lau
Summary: A case management approach led by a nurse and supported by a health-social partnership team was used to sustain app usage among older adults. The results showed improvements in self-efficacy and depression levels for participants who continued using the app.
JOURNAL OF MEDICAL INTERNET RESEARCH
(2023)
Review
Oncology
Nuo Shi, Arkers K. C. Wong, Frances K. Y. Wong, Liyan Sha
Summary: This review identifies the components of existing mobile health app-based interventions for patients with breast cancer who are undergoing chemotherapy and aims to uncover self-efficacy enhancement elements from among them.
Article
Nursing
Sek Ying Chair, Frances Kam Yuet Wong, Denise Bryant-Lukosius, Ting Liu, Krista Jokiniemi
Summary: This study conducted exploratory factor analysis on the core competence scale of advanced practice nurses in Hong Kong, resulting in a three-factor structure with robust internal consistency. The findings can serve as a foundational framework for the development, education, and practice of nursing professionals, as well as inform future competency research.
Article
Nursing
Arkers Kwan Ching Wong, Tommy Tsz Man Hung, Jonathan Bayuo, Frances Kam Yuet Wong
Summary: This study aimed to compare the effects of a blended video watching and peer learning program and the usual lecture-based program on the levels of satisfaction, self-confidence in learning, perceptions of peer learning, and academic performance of master's nursing students. The study found a significant increase in satisfaction, self-confidence, and academic performance in the intervention group after learning in a blended video-watching and peer learning mode.
Review
Nursing
Yi Wang, Frances Kam Yuet Wong, Jonathan Bayuo, Loretta Yuet Foon Chung, Li Zhang, Taotao Wang
Summary: This integrative review aimed to investigate the challenges faced by burn care nurses and burn patients' family members and explore the relationship between them. A total of 17 studies were included in the analysis, which identified key challenges such as ethical and religious issues, clinical problems, work-life imbalance, and limited support for nurses, as well as differences in prognosis and treatment views, work-life imbalance, psychological issues, and lack of multifaceted support for family members. It is important to address these challenges to ensure proper support for burn patients.
Review
Nursing
Erin Ziegler, Ruth Martin-Misener, Sarah Rietkoetter, Andrea Baumann, Ivy Lynn Bougeault, Nikolina Kovacevic, Minna Miller, Jessica Moseley, Frances Kam Yuet Wong, Denise Bryant-Lukosius
Summary: The aim of this study was to identify and map international evidence of innovations led by or involving advanced practice nurses in response to COVID-19. The findings showed that advanced practice nurses played a crucial role in the pandemic response, but their contributions to innovations have not been fully evaluated. This study has significant implications for informing policies, practices, and research on the optimal utilization of advanced practice nurses.
INTERNATIONAL NURSING REVIEW
(2023)
Article
Nursing
Arkers Kwan Ching Wong, Vivian Wai Yan Kwok, Frances Kam Yuet Wong, Danny Wah Kun Tong, Bernard Man Kam Yuen, Ching Sing Fong, Shun Tim Chan, Wah Chun Li, Shiyi Zhou, Athena Yin Lam Lee
Summary: This study aims to evaluate the clinical effectiveness and implementation strategies of telecare consultations in post-stroke nurse-led clinics.
JOURNAL OF ADVANCED NURSING
(2023)
Article
Health Care Sciences & Services
Rick Yiu Cho Kwan, Simon Ching Lam, Shao Ling Wang, Arkers Kwan Ching Wong, Lei Shi, Frances Kam Yuet Wong
Summary: A new instrument (PETS-C Brief) for measuring perceptions of e-health technology among healthcare professionals was developed and validated in this study. Results showed good content and face validities, as well as an acceptable factor structure.
Article
Oncology
Diomidis Antoniadis, Alexander Giakoustidis, Vasileios Papadopoulos, Konstantinos N. Fountoulakis, Maggie Watson
Summary: The purpose of this study was to investigate the relationships between distress, psychological adjustment, and quality of life in patients with colon cancer. The results showed that quality of life was positively correlated with fighting spirit, cognitive avoidance, and fatalism, and negatively correlated with helplessness and hopelessness, and anxious preoccupation.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2024)
Article
Oncology
Irem Gul, Ismail Toygar, Oznur Usta Yesilbalkan
Summary: This study investigated the support needs of carers of cancer patients and how the patient's age and cancer type affect their needs. The study found that carers of older adults and patients with hematological malignancies require more support in various aspects of caregiving.
EUROPEAN JOURNAL OF ONCOLOGY NURSING
(2024)
