Mechanisms underlying the anti-wasting effect of l-carnitine supplementation under pathologic conditions: evidence from experimental and clinical studies
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Title
Mechanisms underlying the anti-wasting effect of l-carnitine supplementation under pathologic conditions: evidence from experimental and clinical studies
Authors
Keywords
<span class=EmphasisTypeSmallCaps >l, Muscle wasting, Cachexia, Proteolysis, Inflammation, Oxidative stress
Journal
EUROPEAN JOURNAL OF NUTRITION
Volume 52, Issue 5, Pages 1421-1442
Publisher
Springer Nature
Online
2013-03-18
DOI
10.1007/s00394-013-0511-0
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Note: Only part of the references are listed.- NF-κB Activation Is Required for the Transition of Pulmonary Inflammation to Muscle Atrophy
- (2012) Ramon C. J. Langen et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Treatment with pharmacological PPARα agonists stimulates the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeletal muscle of rodents
- (2012) Robert Ringseis et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
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- (2012) Sílvia Busquets et al. CLINICAL NUTRITION
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- (2012) S.P. Patel et al. NEUROSCIENCE
- Propionyl-L-carnitine Corrects Metabolic and Cardiovascular Alterations in Diet-Induced Obese Mice and Improves Liver Respiratory Chain Activity
- (2012) Carmen Mingorance et al. PLoS One
- Oral acetyl-l-carnitine therapy reduces fatigue in overt hepatic encephalopathy: a randomized, double-blind, placebo-controlled study
- (2011) Michele Malaguarnera et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
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- (2011) J. Keller et al. Animal
- Protective action of l-carnitine on cardiac mitochondrial function and structure against fatty acid stress
- (2011) Eri Oyanagi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Selenium and l-Carnitine Reduce Oxidative Stress in the Heart of Rat Induced by 2.45-GHz Radiation from Wireless Devices
- (2011) Yasin Türker et al. BIOLOGICAL TRACE ELEMENT RESEARCH
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- (2011) Jiejie Hao et al. BRITISH JOURNAL OF NUTRITION
- L-carnitine ameliorates cancer cachexia in mice by regulating the expression and activity of carnitine palmityl transferase
- (2011) Su Liu et al. CANCER BIOLOGY & THERAPY
- Carnitine Administration Reduces Cytokine Levels, Improves Food Intake, and Ameliorates Body Composition in Tumor-Bearing Rats
- (2011) Alessandro Laviano et al. CANCER INVESTIGATION
- Role of carnitine in the regulation of glucose homeostasis and insulin sensitivity: evidence from in vivo and in vitro studies with carnitine supplementation and carnitine deficiency
- (2011) Robert Ringseis et al. EUROPEAN JOURNAL OF NUTRITION
- Acetyl-L-carnitine-mediated neuroprotection during hypoxia is attributed to ERK1/2-Nrf2-regulated mitochondrial biosynthesis
- (2011) Kalpana Barhwal Hota et al. HIPPOCAMPUS
- Angiotensin II Upregulates Protein Phosphatase 2Cα and Inhibits AMP-Activated Protein Kinase Signaling and Energy Balance Leading to Skeletal Muscle Wasting
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- The Supplementation of Acetyl-l-Carnitine Decreases Fatigue and Increases Quality of Life in Patients with Hepatitis C Treated with Pegylated Interferon-α 2b Plus Ribavirin
- (2011) Michele Malaguarnera et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- L-Carnitine attenuates ifosfamide-induced carnitine deficiency and decreased intramitochondrial CoA-SH in rat kidney tissues
- (2011) Mohamed M. Sayed-Ahmed JOURNAL OF NEPHROLOGY
- Acetyl-l-carnitine prevents carbon tetrachloride-induced oxidative stress in various tissues of Wistar rats
- (2011) Thangaraj Annadurai et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- In vivo neuroprotective effect of L-carnitine against oxidative stress in maple syrup urine disease
- (2011) Caroline Mescka et al. METABOLIC BRAIN DISEASE
- L-carnitine improves oxidative stress and suppressed energy metabolism but not renal dysfunction following release of acute unilateral ureteral obstruction in rat
- (2011) S. Mostafa Shid Moosavi et al. NEUROUROLOGY AND URODYNAMICS
- Doxorubicin Toxicity can be Ameliorated during Antioxidant L-Carnitine Supplementation
- (2011) Othman A. Alshabanah et al. Oxidative Medicine and Cellular Longevity
- The role and regulation of MAFbx/atrogin-1 and MuRF1 in skeletal muscle atrophy
- (2011) Victoria C. Foletta et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Pharmacological interventions for spinal cord injury: Where do we stand? How might we step forward?
- (2011) Alexander G. Rabchevsky et al. PHARMACOLOGY & THERAPEUTICS
- Acetyl-l-carnitine reduces depression and improves quality of life in patients with minimal hepatic encephalopathy
- (2011) Mariano Malaguarnera et al. SCANDINAVIAN JOURNAL OF GASTROENTEROLOGY
- POST-TREATMENT With the Combination of 5-Aminoimidazole-4-Carboxyamide Ribonucleoside and Carnitine Improves Renal Function After Ischemia/Reperfusion Injury
- (2011) Juan-Pablo Idrovo et al. SHOCK
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- (2011) Stefano Schiaffino et al. Skeletal Muscle
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- Effects of Selenium and L-Carnitine on Oxidative Stress in Blood of Rat Induced by 2.45-GHz Radiation from Wireless Devices
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- Nutritional and exercise-based interventions in the treatment of amyotrophic lateral sclerosis
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- L-carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes
- (2009) Hung-Hsin Chao et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Modulator effects of L-carnitine and selenium on wireless devices (2.45 GHz)-induced oxidative stress and electroencephalography records in brain of rat
- (2009) Mustafa Naziroğlu et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Carnitine Plasma Levels and Fatigue in Children/Adolescents Receiving Cisplatin, Ifosfamide, or Doxorubicin
- (2009) Marilyn J. Hockenberry et al. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
- Inhibition of Atrogin-1/MAFbx Mediated MyoD Proteolysis Prevents Skeletal Muscle Atrophy In Vivo
- (2009) Julie Lagirand-Cantaloube et al. PLoS One
- Comparison of the effects of l-carnitine and α-tocopherol on acute ureteral obstruction-induced renal oxidative imbalance and altered energy metabolism in rats
- (2009) S. Mostafa Shid Moosavi et al. UROLOGICAL RESEARCH
- The role of cytokines in cancer cachexia
- (2009) Josep M Argilés et al. Current Opinion in Supportive and Palliative Care
- l-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes
- (2008) Mariano Malaguarnera et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- The Role of Inflammatory Markers in the Cardioprotective Effect of L-Carnitine in L-NAME-Induced Hypertension
- (2008) J. L. Miguel-Carrasco et al. AMERICAN JOURNAL OF HYPERTENSION
- Cachexia: A new definition
- (2008) William J. Evans et al. CLINICAL NUTRITION
- Inflammatory burden and amino acid metabolism in cancer cachexia
- (2008) William J Durham et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- The initiation factor eIF3-f is a major target for Atrogin1/MAFbx function in skeletal muscle atrophy
- (2008) Julie Lagirand-Cantaloube et al. EMBO JOURNAL
- l-carnitine supplementation attenuates intermittent hypoxia-induced oxidative stress and delays muscle fatigue in rats
- (2008) Arkadeb Dutta et al. EXPERIMENTAL PHYSIOLOGY
- Apoptosis signalling is essential and precedes protein degradation in wasting skeletal muscle during catabolic conditions
- (2008) Josep M. Argilés et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Effects of feeding l-carnitine to gilts through day 70 of gestation on litter traits and the expression of insulin-like growth factor system components and l-carnitine concentration in foetal tissues
- (2008) K. R. Brown et al. JOURNAL OF ANIMAL PHYSIOLOGY AND ANIMAL NUTRITION
- MAFbx/Atrogin-1 Controls the Activity of the Initiation Factor eIF3-f in Skeletal Muscle Atrophy by Targeting Multiple C-terminal Lysines
- (2008) Alfredo Csibi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of l-carnitine
- (2008) Daniela Silva-Adaya et al. JOURNAL OF NEUROCHEMISTRY
- L-Carnitine Supplementation in Patients with Advanced Cancer and Carnitine Deficiency: A Double-Blind, Placebo-Controlled Study
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- Randomized phase III clinical trial of five different arms of treatment for patients with cancer cachexia: interim results
- (2008) Giovanni Mantovani et al. NUTRITION
- Signaling in Muscle Atrophy and Hypertrophy
- (2008) Marco Sandri PHYSIOLOGY
- A Combination of Nutriments Improves Mitochondrial Biogenesis and Function in Skeletal Muscle of Type 2 Diabetic Goto–Kakizaki Rats
- (2008) Weili Shen et al. PLoS One
- A DIGE approach for the assessment of rat soleus muscle changes during unloading: effect of acetyl-L-carnitine supplementation
- (2008) Manuela Moriggi et al. PROTEOMICS
- Catabolic mediators of cancer cachexia
- (2008) Michael J Tisdale Current Opinion in Supportive and Palliative Care
- Antimony-induced cardiomyopathy in guinea-pig and protection by L-carnitine
- (2004) Marco Alvarez et al. BRITISH JOURNAL OF PHARMACOLOGY
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