CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model

Endogenous N-Acetylaspartylglutamate (NAAG) Inhibits Synaptic Plasticity/Transmission in the Amygdala in a Mouse Inflammatory Pain Model

(2016) Mary O Adedoyin et al.   Molecular Pain

Cannabinoid CB1 receptors in rat medial prefrontal cortex are colocalized with calbindin but not parvalbumin- and calretinin-positive GABA-ergic neurons

(2014) Krzysztof Wędzony et al.   Pharmacological Reports

Neuropeptide S: a novel regulator of pain-related amygdala plasticity and behaviors

(2013) Wenjie Ren et al.   JOURNAL OF NEUROPHYSIOLOGY

The amygdala and medial prefrontal cortex: partners in the fear circuit

(2013) Roger Marek et al.   JOURNAL OF PHYSIOLOGY-LONDON

Prefrontal cortex and mediodorsal thalamus reduced connectivity is associated with spatial working memory impairment in rats with inflammatory pain

(2013) Helder Cardoso-Cruz et al.   PAIN

Potential Utility of Optogenetics in the Study of Depression

(2012) Mary Kay Lobo et al.   BIOLOGICAL PSYCHIATRY

The Endocannabinoid System and Pain

(2012) Josee Guindon et al.   CNS & Neurological Disorders-Drug Targets

Asymmetric time-dependent activation of right central amygdala neurones in rats with peripheral neuropathy and pregabalin modulation

(2012) Leonor Gonçalves et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

p300/CBP-Associated Factor Selectively Regulates the Extinction of Conditioned Fear

(2012) W. Wei et al.   JOURNAL OF NEUROSCIENCE

Role of Capsaicin-Sensitive C-Fiber Afferents in Neuropathic Pain-Induced Synaptic Potentiation in the Nociceptive Amygdala

(2012) Ayano Nakao et al.   Molecular Pain

Modulation of pyramidal cell output in the medial prefrontal cortex by mGluR5 interacting with CB1

(2012) Takaki Kiritoshi et al.   NEUROPHARMACOLOGY

Medial prefrontal cortical innervation of the intercalated nuclear region of the amygdala

(2012) C.R. Pinard et al.   NEUROSCIENCE

Neural and cellular mechanisms of fear and extinction memory formation

(2012) Caitlin A. Orsini et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Modulation of medial prefrontal cortical activity using in vivo recordings and optogenetics

(2012) Guangchen Ji et al.   Molecular Brain

TRPV1-Dependent and -Independent Alterations in the Limbic Cortex of Neuropathic Mice: Impact on Glial Caspases and Pain Perception

(2011) Catia Giordano et al.   CEREBRAL CORTEX

mGluR1, but not mGluR5, activates feed-forward inhibition in the medial prefrontal cortex to impair decision making

(2011) Hao Sun et al.   JOURNAL OF NEUROPHYSIOLOGY

Physiological identification and infralimbic responsiveness of rat intercalated amygdala neurons

(2011) Alon Amir et al.   JOURNAL OF NEUROPHYSIOLOGY

Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABAA receptors

(2011) Guangchen Ji et al.   JOURNAL OF NEUROPHYSIOLOGY

Different Fear States Engage Distinct Networks within the Intercalated Cell Clusters of the Amygdala

(2011) D. Busti et al.   JOURNAL OF NEUROSCIENCE

Optogenetic neuronal control in schizophrenia

(2011) Avi Peled   MEDICAL HYPOTHESES

Pain-Related Increase of Excitatory Transmission and Decrease of Inhibitory Transmission in the Central Nucleus of the Amygdala are Mediated by mGluR1

(2011) Wenjie Ren et al.   Molecular Pain

Positive Allosteric Modulators of Type 5 Metabotropic Glutamate Receptors (mGluR5) and Their Therapeutic Potential for the Treatment of CNS Disorders

(2011) Richard M. Cleva et al.   MOLECULES

Impulsivity, Compulsivity, and Top-Down Cognitive Control

(2011) Jeffrey W. Dalley et al.   NEURON

Metabotropic glutamate receptors as therapeutic targets for schizophrenia

(2011) Paige N. Vinson et al.   NEUROPHARMACOLOGY

NMDA Receptors, mGluR5 and Endocannabinoids are Involved in a Cascade Leading to Hippocampal Long-Term Depression

(2011) Yukitoshi Izumi et al.   NEUROPSYCHOPHARMACOLOGY

Opposing Roles for Cannabinoid Receptor Type-1 (CB1) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats

(2011) Plínio C Casarotto et al.   NEUROPSYCHOPHARMACOLOGY

The effect of pain on cognitive function: A review of clinical and preclinical research

(2011) Orla Moriarty et al.   PROGRESS IN NEUROBIOLOGY

Transient inactivation of the medial prefrontal cortex affects both anxiety and decision-making in male Wistar rats

(2011) Leonie de Visser   Frontiers in Neuroscience

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

Strain difference in the effect of infralimbic cortex lesions on fear extinction in rats.

(2010) Chun-hui Chang et al.   BEHAVIORAL NEUROSCIENCE

Memory for Fear Extinction Requires mGluR5-Mediated Activation of Infralimbic Neurons

(2010) Darah E. Fontanez-Nuin et al.   CEREBRAL CORTEX

Receptors and Channels Targeted by Synthetic Cannabinoid Receptor Agonists and Antagonists

(2010) R. Pertwee   CURRENT MEDICINAL CHEMISTRY

Prefrontal control of fear: more than just extinction

(2010) Francisco Sotres-Bayon et al.   CURRENT OPINION IN NEUROBIOLOGY

Neuronal circuits of fear extinction

(2010) Cyril Herry et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Lack of Medial Prefrontal Cortex Activation Underlies the Immediate Extinction Deficit

(2010) S. C. Kim et al.   JOURNAL OF NEUROSCIENCE

Erasing Fear Memories with Extinction Training

(2010) G. J. Quirk et al.   JOURNAL OF NEUROSCIENCE

Cognitive Impairment in Pain through Amygdala-Driven Prefrontal Cortical Deactivation

(2010) G. Ji et al.   JOURNAL OF NEUROSCIENCE

Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

(2010) A. L. Rodriguez et al.   MOLECULAR PHARMACOLOGY

Anandamide serves two masters in the brain

(2010) Vincenzo Di Marzo   NATURE NEUROSCIENCE

Synaptic correlates of fear extinction in the amygdala

(2010) Taiju Amano et al.   NATURE NEUROSCIENCE

Endocannabinoid signaling in the brain: biosynthetic mechanisms in the limelight

(2010) Vincenzo Di Marzo   NATURE NEUROSCIENCE

Dissociable Roles of Prelimbic and Infralimbic Cortices, Ventral Hippocampus and Basolateral Amygdala in the Expression and Extinction of Conditioned Fear

(2010) Demetrio Sierra-Mercado et al.   NEUROPSYCHOPHARMACOLOGY

The Pain Imaging Revolution: Advancing Pain Into the 21st Century

(2010) David Borsook et al.   NEUROSCIENTIST

Plastic Synaptic Networks of the Amygdala for the Acquisition, Expression, and Extinction of Conditioned Fear

(2010) Hans-Christian Pape et al.   PHYSIOLOGICAL REVIEWS

Single-Unit Activity in the Medial Prefrontal Cortex during Immediate and Delayed Extinction of Fear in Rats

(2010) Chun-hui Chang et al.   PLoS One

New Findings on Extinction of Conditioned Fear Early in Development: Theoretical and Clinical Implications

(2009) Jee Hyun Kim et al.   BIOLOGICAL PSYCHIATRY

Forebrain pain mechanisms

(2009) Volker Neugebauer et al.   BRAIN RESEARCH REVIEWS

Hemispheric Lateralization of Pain Processing by Amygdala Neurons

(2009) Guangchen Ji et al.   JOURNAL OF NEUROPHYSIOLOGY

Extinction circuits for fear and addiction overlap in prefrontal cortex

(2009) J. Peters et al.   LEARNING & MEMORY

Reciprocal patterns of c-Fos expression in the medial prefrontal cortex and amygdala after extinction and renewal of conditioned fear

(2009) E. Knapska et al.   LEARNING & MEMORY

Amygdala Inhibitory Circuits and the Control of Fear Memory

(2009) Ingrid Ehrlich et al.   NEURON

mGluR5 Positive Allosteric Modulators Facilitate both Hippocampal LTP and LTD and Enhance Spatial Learning

(2009) Jennifer E Ayala et al.   NEUROPSYCHOPHARMACOLOGY

Changing Fear: The Neurocircuitry of Emotion Regulation

(2009) Catherine A Hartley et al.   NEUROPSYCHOPHARMACOLOGY

Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain

(2009) M. Pais-Vieira et al.   NEUROSCIENCE

Endocannabinoid-Mediated Control of Synaptic Transmission

(2009) Masanobu Kano et al.   PHYSIOLOGICAL REVIEWS

Morphological and functional reorganization of rat medial prefrontal cortex in neuropathic pain

(2009) A. E. Metz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Role of Prefrontal Cortex CB1 Receptors in the Modulation of Fear Memory

(2008) H.-C. Lin et al.   CEREBRAL CORTEX

Impaired Fear Extinction Learning and Cortico-Amygdala Circuit Abnormalities in a Common Genetic Mouse Strain

(2008) K. Hefner et al.   JOURNAL OF NEUROSCIENCE

Differential Mechanisms of CRF1 and CRF2 Receptor Functions in the Amygdala in Pain-Related Synaptic Facilitation and Behavior

(2008) Y. Fu et al.   JOURNAL OF NEUROSCIENCE

Chronic cannabinoid administration in vivo compromises extinction of fear memory

(2008) H.-C. Lin et al.   LEARNING & MEMORY

Hemispheric Lateralization of a Molecular Signal for Pain Modulation in the Amygdala

(2008) Yarimar Carrasquillo et al.   Molecular Pain

Amygdala intercalated neurons are required for expression of fear extinction

(2008) Ekaterina Likhtik et al.   NATURE

The circuit of fear

(2008) Pankaj Sah et al.   NATURE

Neuropeptide S-Mediated Control of Fear Expression and Extinction: Role of Intercalated GABAergic Neurons in the Amygdala

(2008) Kay Jüngling et al.   NEURON

Activation of metabotropic glutamate 5 (mGlu5) receptors induces spontaneous excitatory synaptic currents in layer V pyramidal cells of the rat prefrontal cortex

(2008) Gerard J. Marek et al.   NEUROSCIENCE LETTERS

Chronic pain may change the structure of the brain

(2008) Arne May   PAIN

Towards a theory of chronic pain

(2008) A. Vania Apkarian et al.   PROGRESS IN NEUROBIOLOGY