The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond

Cannabinoids increase type 1 cannabinoid receptor expression in a cell culture model of striatal neurons: Implications for Huntington's disease

(2013) Robert B. Laprairie et al.   NEUROPHARMACOLOGY

CB1 cannabinoid receptor agonist prevents NGF-induced sensitization of TRPV1 in sensory neurons

(2013) Thomas S. McDowell et al.   NEUROSCIENCE LETTERS

Antinociceptive effects of the selective CB2 agonist MT178 in inflammatory and chronic rodent pain models

(2013) Fabrizio Vincenzi et al.   PAIN

BDNF Depresses Excitability of Parvalbumin-Positive Interneurons through an M-Like Current in Rat Dentate Gyrus

(2013) Jose Luis Nieto-Gonzalez et al.   PLoS One

Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons

(2013) E. Keimpema et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation-dependent plasticity of polarized GPCR distribution on the neuronal surface

(2013) Anne C. Simon et al.   Journal of Molecular Cell Biology

Endocannabinoid-dependent plasticity at spinal nociceptor synapses

(2012) Ako Kato et al.   JOURNAL OF PHYSIOLOGY-LONDON

TRPV1 is important for mechanical and heat sensitivity in uninjured animals and development of heat hypersensitivity after muscle inflammation

(2012) Roxanne Y. Walder et al.   PAIN

The role of CB1 in immune modulation by cannabinoids

(2012) Barbara L.F. Kaplan   PHARMACOLOGY & THERAPEUTICS

Synapse type-independent degradation of the endocannabinoid 2-arachidonoylglycerol after retrograde synaptic suppression

(2012) Asami Tanimura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Excitability of prefrontal cortical pyramidal neurons is modulated by activation of intracellular type-2 cannabinoid receptors

(2012) F. S. den Boon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocannabinoids inhibit release of nerve growth factor by inflammation-activated mast cells

(2011) Giuseppina Cantarella et al.   BIOCHEMICAL PHARMACOLOGY

ξUp-regulation of dorsal root ganglia BDNF and trkB receptor in inflammatory pain: an in vivo and in vitro study

(2011) Ya-Tin Lin et al.   Journal of Neuroinflammation

Concerted Action of CB1 Cannabinoid Receptor and Deleted in Colorectal Cancer in Axon Guidance

(2011) A. Argaw et al.   JOURNAL OF NEUROSCIENCE

Endocannabinoid Hydrolysis Generates Brain Prostaglandins That Promote Neuroinflammation

(2011) D. K. Nomura et al.   SCIENCE

Molecular model of cannabis sensitivity in developing neuronal circuits

(2011) Erik Keimpema et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The RING heterodimer BRCA1–BARD1 is a ubiquitin ligase inactivated by the platinum-based anticancer drugs

(2010) Apichart Atipairin et al.   BREAST CANCER RESEARCH AND TREATMENT

Requirement of cannabinoid CB1 receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections

(2010) Chia-Shan Wu et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Rimonabant, a cannabinoid CB1 receptor antagonist, attenuates mechanical allodynia and counteracts oxidative stress and nerve growth factor deficit in diabetic mice

(2010) Francesca Comelli et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Epidermal growth factor receptor transactivation by the cannabinoid receptor (CB1) and transient receptor potential vanilloid 1 (TRPV1) induces differential responses in corneal epithelial cells

(2010) H. Yang et al.   EXPERIMENTAL EYE RESEARCH

BDNF Evokes Release of Endogenous Cannabinoids at Layer 2/3 Inhibitory Synapses in the Neocortex

(2010) Fouad Lemtiri-Chlieh et al.   JOURNAL OF NEUROPHYSIOLOGY

Brain-Derived Neurotrophic Factor Controls Cannabinoid CB1 Receptor Function in the Striatum

(2010) V. De Chiara et al.   JOURNAL OF NEUROSCIENCE

Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism

(2010) Jason R Clapper et al.   NATURE NEUROSCIENCE

The serine hydrolase ABHD6 controls the accumulation and efficacy of 2-AG at cannabinoid receptors

(2010) William R Marrs et al.   NATURE NEUROSCIENCE

Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system

(2010) Joel E Schlosburg et al.   NATURE NEUROSCIENCE

Depression-like phenotype following chronic CB1 receptor antagonism

(2010) Chad E. Beyer et al.   NEUROBIOLOGY OF DISEASE

Dissecting the involvement of tropomyosin-related kinase A and p75 neurotrophin receptor signaling in NGF deficit-induced neurodegeneration

(2010) S. Capsoni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intrathecal NGF Administration Reduces Reactive Astrocytosis and Changes Neurotrophin Receptors Expression Pattern in a Rat Model of Neuropathic Pain

(2009) Giovanni Cirillo et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Origin, Early Commitment, Migratory Routes, and Destination of Cannabinoid Type 1 Receptor-Containing Interneurons

(2009) Yury M. Morozov et al.   CEREBRAL CORTEX

Molecular architecture of endocannabinoid signaling at nociceptive synapses mediating analgesia

(2009) Rita Nyilas et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Cannabinoid 1 Receptor and Interleukin-6 Receptor Together Induce Integration of Protein Kinase and Transcription Factor Signaling to Trigger Neurite Outgrowth

(2009) Yana Zorina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular and Structural Insight into proNGF Engagement of p75NTR and Sortilin

(2009) Dan Feng et al.   JOURNAL OF MOLECULAR BIOLOGY

The FGF family: biology, pathophysiology and therapy

(2009) Andrew Beenken et al.   NATURE REVIEWS DRUG DISCOVERY

Role of BDNF and GDNF in drug reward and relapse: A review

(2009) Udi E. Ghitza et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

BDNF regulates neuronal sensitivity to endocannabinoids

(2009) Patrick Maison et al.   NEUROSCIENCE LETTERS

Endocannabinoid-Mediated Control of Synaptic Transmission

(2009) Masanobu Kano et al.   PHYSIOLOGICAL REVIEWS

Spinal Endocannabinoids and CB1 Receptors Mediate C-Fiber-Induced Heterosynaptic Pain Sensitization

(2009) A. J. Pernia-Andrade et al.   SCIENCE

Modulation of the anti-nociceptive effects of 2-arachidonoyl glycerol by peripherally administered FAAH and MGL inhibitors in a neuropathic pain model

(2008) J Desroches et al.   BRITISH JOURNAL OF PHARMACOLOGY

The type 1 cannabinoid receptor is highly expressed in embryonic cortical projection neurons and negatively regulates neurite growthin vitro

(2008) Tania Vitalis et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1knockout mice

(2008) Ester Aso et al.   JOURNAL OF NEUROCHEMISTRY

Roles of Endocannabinoids in Heterosynaptic Long-Term Depression of Excitatory Synaptic Transmission in Visual Cortex of Young Mice

(2008) Y. Huang et al.   JOURNAL OF NEUROSCIENCE

Endocannabinoid functions controlling neuronal specification during brain development

(2008) Tibor Harkany et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

(2008) Jonathan Z Long et al.   Nature Chemical Biology

Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum

(2008) Mauro Maccarrone et al.   NATURE NEUROSCIENCE

GPR55 is a cannabinoid receptor that increases intracellular calcium and inhibits M current

(2008) J. E. Lauckner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning

(2008) J. Mulder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BDNF as a pain modulator

(2008) A MERIGHI et al.   PROGRESS IN NEUROBIOLOGY

Preliminary evidence of cannabinoid effects on brain-derived neurotrophic factor (BDNF) levels in humans

(2008) Deepak Cyril D’Souza et al.   PSYCHOPHARMACOLOGY

Chronic exposure of sensory neurones to increased levels of nerve growth factor modulates CB1/TRPV1 receptor crosstalk

(2007) R M Evans et al.   BRITISH JOURNAL OF PHARMACOLOGY

The novel endocannabinoid receptor GPR55 is activated by atypical cannabinoids but does not mediate their vasodilator effects

(2007) D G Johns et al.   BRITISH JOURNAL OF PHARMACOLOGY

Multiple pathways involved in the biosynthesis of anandamide

(2007) Jie Liu et al.   NEUROPHARMACOLOGY