Article
Neurosciences
Darlene R. Archer, Henry J. Alitto, W. Martin Usrey
Summary: Stimulus contrast affects spatial integration in the lateral geniculate nucleus, resulting in reduced extraclassical surround suppression and larger preferred stimulus size with low-contrast stimuli. Effects are more pronounced in magnocellular neurons, suggesting stream-specific interactions between stimulus contrast and size. Contrast-dependent effects are comparable in ON-center and OFF-center neurons within the magnocellular pathway, indicating differential interactions between stimulus contrast and size to improve stimulus detection and discrimination under pathway-specific contrast conditions.
JOURNAL OF NEUROSCIENCE
(2021)
Article
Biochemical Research Methods
Omri David Gilday, Benedikt Praegel, Ido Maor, Tav Cohen, Israel Nelken, Adi Mizrahi
Summary: Surround suppression is a fundamental property of sensory processing in the brain. This study found that there is bandwidth tuning in the auditory system, and proposed a simple explanation for auditory edge detection.
PLOS COMPUTATIONAL BIOLOGY
(2023)
Article
Agriculture, Dairy & Animal Science
Xiaoke Niu, Shuman Huang, Minjie Zhu, Zhizhong Wang, Li Shi
Summary: This study analyzed the surround modulation properties of avian tectum neurons and found that the inhibitory responses appear to be full surrounding rather than locally lateral. This is important for understanding the mechanism of target detection against clutter background in birds.
Article
Multidisciplinary Sciences
Sunny Nigam, Sorin Pojoga, Valentin Dragoi
Summary: Research has identified a distinct population of cells in macaque visual cortex that have a heterogeneous receptive field structure, where individual subfields are tuned to different colors despite weak overall tuning. This spatial heterogeneity in color tuning suggests a higher level of complexity in color-encoding mechanisms in the visual cortex than previously thought, aiding in the efficient extraction of chromatic information from the environment.
Article
Multidisciplinary Sciences
Sarah Strauss, Maria M. Korympidou, Yanli Ran, Katrin Franke, Timm Schubert, Tom Baden, Philipp Berens, Thomas Euler, Anna L. Vlasits
Summary: Motion sensing is a crucial aspect of vision. Research on mouse retinal bipolar cells has revealed the presence of radial direction selectivity, with some cells preferring the origin of small object motion trajectories. This selectivity relies on the properties of the center-surround receptive field. By studying these cells and using connectomics, biophysical models were developed to understand how their selectivity contributes to downstream cells. It was found that bipolar cells pass radial direction selective excitation to starburst amacrine cells, contributing to their directional tuning and potentially impacting motion processing throughout the visual system.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Fusao Kawai
Summary: Retinal horizontal cells have broad receptive fields that contribute to generating antagonistic surround responses in retinal bipolar cells. This study found that depolarizing responses of yellow/red, blue-type horizontal cells exhibit a larger receptive field than hyperpolarizing responses at monochromatic lights between 480 nm and 520 nm. The depolarization or hyperpolarization of these cells may regulate the size of the surround receptive field in bipolar cells, which play a key role in visual contrast detection.
JOURNAL OF NEUROPHYSIOLOGY
(2022)
Article
Ophthalmology
Bao N. Nguyen, Bhavatharini Ramakrishnan, Anuradha Narayanan, Jameel R. Hussaindeen, Allison M. McKendrick
Summary: This study found that early adolescents show weaker center-surround contrast suppression compared to adults.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2023)
Article
Multidisciplinary Sciences
Dylan Festa, Amir Aschner, Aida Davila, Adam Kohn, Ruben Coen-Cagli
Summary: This study combines analysis of image statistics and recordings in macaque V1 to demonstrate that probabilistic inference tuned to natural image statistics can explain the relationship between spike count variance and mean as well as the modulation of V1 activity and variability by spatial context in images. The results show that variability in cortical responses can be explained by a probabilistic representation tuned to naturalistic inputs, supporting the neural sampling theory that neuronal variability encodes the uncertainty of probabilistic inferences. This paper highlights that response variability in primary visual cortex reflects the statistical structure of visual inputs, which is essential for inferences correctly tuned to the statistics of the natural environment.
NATURE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Dario L. Ringach
Summary: The research reveals that in the primary visual cortex, only a small number (approximately 2-6) of thalamic input neurons account for 90% of the total synaptic weight to a cortical neuron. These results indicate that the convergence of a few inputs partly determines the retinotopy and tuning properties of cortical cells.
Article
Cell Biology
Yin Yang, Ke Chen, Marcello G. P. Rosa, Hsin-Hao Yu, Li-Rong Kuang, Jie Yang
Summary: Physiological characteristics of marmoset V2 neurons are similar to V1 neurons, with orientation selectivity and separable spatial/temporal frequency curves playing important roles in visual processing.
NEURAL REGENERATION RESEARCH
(2021)
Article
Neurosciences
Viljami Salmela, Lumikukka Socada, John Soderholm, Roope Heikkila, Jari Lahti, Jesper Ekelund, Erkki Isometsa
Summary: This study behaviorally measured contrast perception in patients with major depressive disorder. The results showed significantly lower contrast suppression in patients compared to controls, while brightness induction was similar. This alteration in visual contrast processing may be present in multiple types of depression and partially normalize upon remission.
JOURNAL OF PSYCHIATRY & NEUROSCIENCE
(2021)
Article
Multidisciplinary Sciences
Jian Ding, Zheng Ye, Fei Xu, Xiangmei Hu, Hao Yu, Shen Zhang, Yanni Tu, Qiuyu Zhang, Qingyan Sun, Tianmiao Hua, Zhong-Lin Lu
Summary: This study explores the relative contributions of higher-order and primary visual cortex to visual perception by modulating transcranial direct current stimulation. The findings suggest that suppressing top-down influence of the higher-order visual cortex reduces behavioral and neuronal contrast sensitivity and increases contrast thresholds. Additionally, the study indicates that the top-down influence increases contrast sensitivity by reducing internal additive noise and the impact of external noise.
Article
Multidisciplinary Sciences
John A. Gaynes, Samuel A. Budoff, Michael J. Grybko, Joshua B. Hunt, Alon Poleg-Polsky
Summary: Antagonistic interactions between center and surround receptive field components are crucial in visual computations. We found that bipolar cells enhance responses to objects in their receptive field and show altered dynamics during continuous motion.
NATURE COMMUNICATIONS
(2022)
Article
Neurosciences
Busra Tugce Gurbuz, Huseyin Boyaci
Summary: This research demonstrates that the tilt aftereffect (TAE) not only occurs at the location of the adapter, but also spreads to other locations in the visual field. Through experiments, the researchers found TAE magnitudes in all tested locations and built a computational model to explain the neural mechanisms underlying this spread.
Article
Multidisciplinary Sciences
Bin Zhao, Rong Wang, Zhihua Zhu, Qianli Yang, Aihua Chen
Summary: The macaque Visual Posterior Sylvian (VPS) area contains neurons that selectively respond to heading direction in both visual and vestibular modalities. However, it is unclear how these neurons combine the two sensory signals. Unlike the medial superior temporal area (MSTd), which shows subadditive characteristics, VPS responses are dominated by vestibular signals. Information analysis reveals that VPS encodes information from distinct sensory modalities, similar to MSTd, but with more emphasis on vestibular signals. Single neuron responses in both areas can be well explained by a weighted linear sum of unimodal responses. Additionally, normalization models capture the interaction characteristics between vestibular and visual signals in both VPS and MSTd, indicating the presence of divisive normalization mechanism in the cortex.
Article
Cell Biology
Shigeki Kato, Ryoji Fukabori, Kayo Nishizawa, Kana Okada, Nozomu Yoshioka, Masateru Sugawara, Yuko Maejima, Kenju Shimomura, Masahiro Okamoto, Satoshi Eifuku, Kazuto Kobayashi
Article
Neurosciences
Akiya Watakabe, Yusuke Komatsu, Osamu Sadakane, Satoshi Shimegi, Toru Takahata, Noriyuki Higo, Shiro Tochitani, Tsutomu Hashikawa, Tomoyuki Naito, Hironobu Osaki, Hiroshi Sakamoto, Masahiro Okamoto, Ayako Ishikawa, Shin-ichiro Hara, Takafumi Akasaki, Hiromichi Sato, Tetsuo Yamamori
Article
Neurosciences
Hironobu Osaki, Tomoyuki Naito, Osamu Sadakane, Masahiro Okamoto, Hiromichi Sato
EUROPEAN JOURNAL OF NEUROSCIENCE
(2011)
Article
Neurosciences
Akihiro Kimura, Satoshi Shimegi, Shin'ichiro Hara, Masahiro Okamoto, Hiromichi Sato
EUROPEAN JOURNAL OF NEUROSCIENCE
(2013)
Article
Neurosciences
Takenobu Murakami, Mitsunari Abe, Winnugroho Wiratman, Juri Fujiwara, Masahiro Okamoto, Tomomi Mizuochi-Endo, Ttoshild Iwabuchi, Michiru Makuuchi, Akira Yamashita, Amanda Tiksnadi, Fang-Yu Chang, Hitoshi Kubo, Nozomu Matsuda, Shunsuke Kobayashi, Satoshi Eifuku, Yoshikazu Ugawa
JOURNAL OF NEUROSCIENCE
(2018)
Meeting Abstract
Neurosciences
Tadahiro Katayama, Eiichi Jodo, Masahiro Okamoto, Yoshiaki Suzuki, Ken-Yo Hoshino, Yukihiko Kayama
NEUROSCIENCE RESEARCH
(2009)
Meeting Abstract
Neurosciences
Tadahiro Katayama, Eiichi Jodo, Masahiro Okamoto, Yoshiaki Suzuki, Ken-Yo Hoshino, Yukihiko Kayama
NEUROSCIENCE RESEARCH
(2010)
Meeting Abstract
Neurosciences
Masahiro Okamoto, Eiichi Jodo, Tadahiro Katayama, Yoshiaki Suzuki, Ken-Yo Hoshino, Hiroshi Yamada, Shinya Matsuoka, Yukihiko Kayama
NEUROSCIENCE RESEARCH
(2010)
Meeting Abstract
Neurosciences
Masahiro Okamoto, Tadahiro Katayama, Yoshiaki Suzuki, Ken-Yo Hoshino, Eiichi Jodo
NEUROSCIENCE RESEARCH
(2011)
Article
Neurosciences
Tomoyuki Naito, Masahiro Okamoto, Osamu Sadakane, Satoshi Shimegi, Hironobu Osaki, Shin-Ichiro Hara, Akihiro Kimura, Ayako Ishikawa, Naofumi Suematsu, Hiromichi Sato
NEUROSCIENCE RESEARCH
(2013)
Meeting Abstract
Psychiatry
Tadahiro Katayama, Eiichi Jodo, Masahiro Okamoto, Yoshiaki Suzuki, Ken-Yo Hoshino, Yukihiko Kayama
SCHIZOPHRENIA RESEARCH
(2010)
Article
Ophthalmology
Tetsuju Sekiryu, Yukinori Sugano, Akira Ojima, Takafumi Mori, Minoru Furuta, Masahiro Okamoto, Satoshi Eifuku
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2019)
Article
Multidisciplinary Sciences
Shingo Tsuji, Tetsuju Sekiryu, Yukinori Sugano, Akira Ojima, Akihito Kasai, Masahiro Okamoto, Satoshi Eifuku
SCIENTIFIC REPORTS
(2020)
Meeting Abstract
Ophthalmology
Tetsuju Sekiryu, Masahiro Okamoto, Satoshi Eifuku, Yukinori Sugano
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2019)